| Full name: keratin 80 | Alias Symbol: KB20 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 144501 | HGNC ID: HGNC:27056 | Ensembl Gene: ENSG00000167767 | OMIM ID: 611161 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT80:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT80 | 144501 | 231849_at | -0.7821 | 0.5898 | |
| GSE26886 | KRT80 | 144501 | 231849_at | -2.6985 | 0.0000 | |
| GSE45670 | KRT80 | 144501 | 231849_at | 0.3049 | 0.5109 | |
| GSE53622 | KRT80 | 144501 | 169644 | -0.9765 | 0.0109 | |
| GSE53624 | KRT80 | 144501 | 169644 | -1.7351 | 0.0000 | |
| GSE63941 | KRT80 | 144501 | 231849_at | 3.3253 | 0.0091 | |
| GSE77861 | KRT80 | 144501 | 231849_at | -0.2949 | 0.5778 | |
| GSE97050 | KRT80 | 144501 | A_24_P331704 | 0.6321 | 0.2827 | |
| SRP007169 | KRT80 | 144501 | RNAseq | -3.4074 | 0.0000 | |
| SRP008496 | KRT80 | 144501 | RNAseq | -2.6997 | 0.0000 | |
| SRP064894 | KRT80 | 144501 | RNAseq | -1.6617 | 0.0011 | |
| SRP133303 | KRT80 | 144501 | RNAseq | -0.8174 | 0.0528 | |
| SRP159526 | KRT80 | 144501 | RNAseq | -2.4609 | 0.0001 | |
| SRP193095 | KRT80 | 144501 | RNAseq | -1.2168 | 0.0005 | |
| SRP219564 | KRT80 | 144501 | RNAseq | -2.9437 | 0.0078 | |
| TCGA | KRT80 | 144501 | RNAseq | 1.0590 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 8.
Survival by KRT80 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT80:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT80 | 144501 | 8 | 1 | 21 | |
| GSE20123 | KRT80 | 144501 | 8 | 1 | 21 | |
| GSE43470 | KRT80 | 144501 | 3 | 0 | 40 | |
| GSE46452 | KRT80 | 144501 | 7 | 1 | 51 | |
| GSE47630 | KRT80 | 144501 | 10 | 2 | 28 | |
| GSE54993 | KRT80 | 144501 | 0 | 5 | 65 | |
| GSE54994 | KRT80 | 144501 | 3 | 2 | 48 | |
| GSE60625 | KRT80 | 144501 | 0 | 0 | 11 | |
| GSE74703 | KRT80 | 144501 | 3 | 0 | 33 | |
| GSE74704 | KRT80 | 144501 | 5 | 1 | 14 | |
| TCGA | KRT80 | 144501 | 12 | 11 | 73 |
Total number of gains: 59; Total number of losses: 24; Total Number of normals: 405.
Somatic mutations of KRT80:
Generating mutation plots.
Highly correlated genes for KRT80:
Showing top 20/864 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT80 | CERS3 | 0.796463 | 5 | 0 | 5 |
| KRT80 | SPRR2D | 0.774681 | 4 | 0 | 4 |
| KRT80 | MAB21L3 | 0.769686 | 4 | 0 | 4 |
| KRT80 | SPRR2B | 0.766191 | 4 | 0 | 4 |
| KRT80 | MPZL2 | 0.764642 | 6 | 0 | 6 |
| KRT80 | SPRR2E | 0.753916 | 4 | 0 | 4 |
| KRT80 | KLK11 | 0.752717 | 6 | 0 | 6 |
| KRT80 | SPRR1B | 0.750021 | 7 | 0 | 6 |
| KRT80 | CXCR2 | 0.748949 | 4 | 0 | 4 |
| KRT80 | TMEM40 | 0.745577 | 7 | 0 | 7 |
| KRT80 | RAB27B | 0.744793 | 5 | 0 | 5 |
| KRT80 | TGM1 | 0.744466 | 7 | 0 | 6 |
| KRT80 | EPHX3 | 0.743463 | 5 | 0 | 5 |
| KRT80 | SPRR2F | 0.739536 | 4 | 0 | 4 |
| KRT80 | LCN2 | 0.738581 | 7 | 0 | 7 |
| KRT80 | IL1RN | 0.738546 | 6 | 0 | 6 |
| KRT80 | TMPRSS11D | 0.73602 | 6 | 0 | 5 |
| KRT80 | GALNT5 | 0.73472 | 3 | 0 | 3 |
| KRT80 | PRSS3 | 0.731382 | 6 | 0 | 5 |
| KRT80 | ARNTL2 | 0.73029 | 6 | 0 | 6 |
For details and further investigation, click here
