| Full name: lactamase beta 2 | Alias Symbol: CGI-83 | ||
| Type: protein-coding gene | Cytoband: 8q13.3 | ||
| Entrez ID: 51110 | HGNC ID: HGNC:18512 | Ensembl Gene: ENSG00000147592 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LACTB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LACTB2 | 51110 | 218701_at | -0.2918 | 0.8634 | |
| GSE20347 | LACTB2 | 51110 | 218701_at | 0.8505 | 0.0024 | |
| GSE23400 | LACTB2 | 51110 | 218701_at | 0.5594 | 0.0000 | |
| GSE26886 | LACTB2 | 51110 | 218701_at | 0.3222 | 0.4417 | |
| GSE29001 | LACTB2 | 51110 | 218701_at | 0.8517 | 0.0262 | |
| GSE38129 | LACTB2 | 51110 | 218701_at | 0.8394 | 0.0001 | |
| GSE45670 | LACTB2 | 51110 | 222714_s_at | 0.5604 | 0.0406 | |
| GSE53622 | LACTB2 | 51110 | 46575 | 0.4423 | 0.0000 | |
| GSE53624 | LACTB2 | 51110 | 46575 | 0.7118 | 0.0000 | |
| GSE63941 | LACTB2 | 51110 | 222714_s_at | 0.2213 | 0.7381 | |
| GSE77861 | LACTB2 | 51110 | 222714_s_at | 1.0670 | 0.0313 | |
| GSE97050 | LACTB2 | 51110 | A_23_P252711 | 0.4926 | 0.2907 | |
| SRP007169 | LACTB2 | 51110 | RNAseq | 0.5351 | 0.1966 | |
| SRP008496 | LACTB2 | 51110 | RNAseq | 0.5807 | 0.0640 | |
| SRP064894 | LACTB2 | 51110 | RNAseq | 1.1533 | 0.0000 | |
| SRP133303 | LACTB2 | 51110 | RNAseq | 0.8777 | 0.0042 | |
| SRP159526 | LACTB2 | 51110 | RNAseq | 0.6159 | 0.0321 | |
| SRP193095 | LACTB2 | 51110 | RNAseq | 0.1533 | 0.4570 | |
| SRP219564 | LACTB2 | 51110 | RNAseq | 0.0762 | 0.7914 | |
| TCGA | LACTB2 | 51110 | RNAseq | 0.0430 | 0.5641 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by LACTB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LACTB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LACTB2 | 51110 | 15 | 1 | 14 | |
| GSE20123 | LACTB2 | 51110 | 16 | 1 | 13 | |
| GSE43470 | LACTB2 | 51110 | 18 | 1 | 24 | |
| GSE46452 | LACTB2 | 51110 | 20 | 2 | 37 | |
| GSE47630 | LACTB2 | 51110 | 23 | 1 | 16 | |
| GSE54993 | LACTB2 | 51110 | 0 | 19 | 51 | |
| GSE54994 | LACTB2 | 51110 | 30 | 0 | 23 | |
| GSE60625 | LACTB2 | 51110 | 0 | 4 | 7 | |
| GSE74703 | LACTB2 | 51110 | 15 | 1 | 20 | |
| GSE74704 | LACTB2 | 51110 | 11 | 0 | 9 | |
| TCGA | LACTB2 | 51110 | 51 | 2 | 43 |
Total number of gains: 199; Total number of losses: 32; Total Number of normals: 257.
Somatic mutations of LACTB2:
Generating mutation plots.
Highly correlated genes for LACTB2:
Showing top 20/422 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LACTB2 | PAFAH1B2 | 0.751728 | 3 | 0 | 3 |
| LACTB2 | MTERF3 | 0.712511 | 6 | 0 | 6 |
| LACTB2 | ARMC1 | 0.692045 | 10 | 0 | 10 |
| LACTB2 | MTFR2 | 0.682732 | 3 | 0 | 3 |
| LACTB2 | PASK | 0.680021 | 3 | 0 | 3 |
| LACTB2 | SPRR4 | 0.673511 | 3 | 0 | 3 |
| LACTB2 | ABCA12 | 0.664138 | 3 | 0 | 3 |
| LACTB2 | MTFR1 | 0.648576 | 11 | 0 | 10 |
| LACTB2 | MPLKIP | 0.637812 | 4 | 0 | 3 |
| LACTB2 | RFC5 | 0.636282 | 6 | 0 | 5 |
| LACTB2 | SLC25A32 | 0.636187 | 10 | 0 | 9 |
| LACTB2 | GGH | 0.633993 | 10 | 0 | 9 |
| LACTB2 | METTL23 | 0.633311 | 5 | 0 | 5 |
| LACTB2 | PTPRA | 0.631765 | 3 | 0 | 3 |
| LACTB2 | MRPL15 | 0.630999 | 9 | 0 | 7 |
| LACTB2 | DPY19L4 | 0.629224 | 11 | 0 | 10 |
| LACTB2 | COPS5 | 0.620496 | 11 | 0 | 10 |
| LACTB2 | BEND3 | 0.620417 | 3 | 0 | 3 |
| LACTB2 | TXNDC12 | 0.619275 | 6 | 0 | 5 |
| LACTB2 | RAD21 | 0.613092 | 9 | 0 | 9 |
For details and further investigation, click here
