| Full name: ST6 beta-galactoside alpha-2,6-sialyltransferase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q27.3 | ||
| Entrez ID: 6480 | HGNC ID: HGNC:10860 | Ensembl Gene: ENSG00000073849 | OMIM ID: 109675 |
| Drug and gene relationship at DGIdb | |||
Expression of ST6GAL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST6GAL1 | 6480 | 201998_at | -0.2463 | 0.8508 | |
| GSE20347 | ST6GAL1 | 6480 | 201998_at | 0.4780 | 0.0502 | |
| GSE23400 | ST6GAL1 | 6480 | 201998_at | 0.1402 | 0.0983 | |
| GSE26886 | ST6GAL1 | 6480 | 201998_at | 0.7376 | 0.0818 | |
| GSE29001 | ST6GAL1 | 6480 | 201998_at | 0.3336 | 0.2900 | |
| GSE38129 | ST6GAL1 | 6480 | 201998_at | 0.3238 | 0.2829 | |
| GSE45670 | ST6GAL1 | 6480 | 201998_at | -0.4766 | 0.2518 | |
| GSE53622 | ST6GAL1 | 6480 | 2868 | 0.0428 | 0.8557 | |
| GSE53624 | ST6GAL1 | 6480 | 2868 | -0.3237 | 0.0917 | |
| GSE63941 | ST6GAL1 | 6480 | 201998_at | 0.5331 | 0.7027 | |
| GSE77861 | ST6GAL1 | 6480 | 201998_at | 0.5078 | 0.1929 | |
| GSE97050 | ST6GAL1 | 6480 | A_24_P388528 | 0.6571 | 0.2074 | |
| SRP007169 | ST6GAL1 | 6480 | RNAseq | 1.4346 | 0.0587 | |
| SRP008496 | ST6GAL1 | 6480 | RNAseq | 1.8006 | 0.0007 | |
| SRP064894 | ST6GAL1 | 6480 | RNAseq | 0.2421 | 0.4342 | |
| SRP133303 | ST6GAL1 | 6480 | RNAseq | 0.2697 | 0.3109 | |
| SRP159526 | ST6GAL1 | 6480 | RNAseq | -0.2108 | 0.7850 | |
| SRP193095 | ST6GAL1 | 6480 | RNAseq | 0.5162 | 0.1505 | |
| SRP219564 | ST6GAL1 | 6480 | RNAseq | 0.5729 | 0.0339 | |
| TCGA | ST6GAL1 | 6480 | RNAseq | -0.3106 | 0.0314 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ST6GAL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST6GAL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST6GAL1 | 6480 | 24 | 0 | 6 | |
| GSE20123 | ST6GAL1 | 6480 | 24 | 0 | 6 | |
| GSE43470 | ST6GAL1 | 6480 | 23 | 1 | 19 | |
| GSE46452 | ST6GAL1 | 6480 | 19 | 1 | 39 | |
| GSE47630 | ST6GAL1 | 6480 | 27 | 2 | 11 | |
| GSE54993 | ST6GAL1 | 6480 | 1 | 19 | 50 | |
| GSE54994 | ST6GAL1 | 6480 | 39 | 0 | 14 | |
| GSE60625 | ST6GAL1 | 6480 | 0 | 6 | 5 | |
| GSE74703 | ST6GAL1 | 6480 | 20 | 1 | 15 | |
| GSE74704 | ST6GAL1 | 6480 | 16 | 0 | 4 | |
| TCGA | ST6GAL1 | 6480 | 77 | 0 | 19 |
Total number of gains: 270; Total number of losses: 30; Total Number of normals: 188.
Somatic mutations of ST6GAL1:
Generating mutation plots.
Highly correlated genes for ST6GAL1:
Showing top 20/472 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST6GAL1 | TBP | 0.754309 | 3 | 0 | 3 |
| ST6GAL1 | DDX11 | 0.747685 | 3 | 0 | 3 |
| ST6GAL1 | PDE7A | 0.746354 | 3 | 0 | 3 |
| ST6GAL1 | DHCR7 | 0.736105 | 3 | 0 | 3 |
| ST6GAL1 | CLSTN1 | 0.735708 | 3 | 0 | 3 |
| ST6GAL1 | CDCA2 | 0.726414 | 3 | 0 | 3 |
| ST6GAL1 | FAM161A | 0.722276 | 3 | 0 | 3 |
| ST6GAL1 | HAUS1 | 0.72114 | 3 | 0 | 3 |
| ST6GAL1 | CXCL5 | 0.720234 | 3 | 0 | 3 |
| ST6GAL1 | STEAP1 | 0.719823 | 3 | 0 | 3 |
| ST6GAL1 | UBE2C | 0.716348 | 3 | 0 | 3 |
| ST6GAL1 | FOXC2 | 0.715945 | 3 | 0 | 3 |
| ST6GAL1 | KCNE3 | 0.709233 | 4 | 0 | 4 |
| ST6GAL1 | TAF4B | 0.696592 | 4 | 0 | 4 |
| ST6GAL1 | SLAMF6 | 0.692108 | 5 | 0 | 5 |
| ST6GAL1 | CXCR4 | 0.69189 | 12 | 0 | 12 |
| ST6GAL1 | CLDN12 | 0.691709 | 3 | 0 | 3 |
| ST6GAL1 | PARVG | 0.688557 | 4 | 0 | 4 |
| ST6GAL1 | TNFRSF10B | 0.686981 | 3 | 0 | 3 |
| ST6GAL1 | NIPSNAP1 | 0.686914 | 3 | 0 | 3 |
For details and further investigation, click here
