| Full name: ring finger protein 183 | Alias Symbol: MGC4734 | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 138065 | HGNC ID: HGNC:28721 | Ensembl Gene: ENSG00000165188 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RNF183:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF183 | 138065 | 235153_at | -1.1140 | 0.1581 | |
| GSE26886 | RNF183 | 138065 | 235153_at | -1.4616 | 0.0017 | |
| GSE45670 | RNF183 | 138065 | 235153_at | 0.1608 | 0.7793 | |
| GSE53622 | RNF183 | 138065 | 72615 | -1.7486 | 0.0000 | |
| GSE53624 | RNF183 | 138065 | 72615 | -1.9597 | 0.0000 | |
| GSE63941 | RNF183 | 138065 | 235153_at | 0.2452 | 0.7394 | |
| GSE77861 | RNF183 | 138065 | 235153_at | 0.0213 | 0.9724 | |
| GSE97050 | RNF183 | A_21_P0014241 | 0.2741 | 0.4891 | ||
| SRP133303 | RNF183 | 138065 | RNAseq | -1.5565 | 0.0474 | |
| SRP159526 | RNF183 | 138065 | RNAseq | 1.1853 | 0.3574 | |
| TCGA | RNF183 | 138065 | RNAseq | -0.8244 | 0.1315 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by RNF183 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF183:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF183 | 138065 | 4 | 10 | 16 | |
| GSE20123 | RNF183 | 138065 | 4 | 10 | 16 | |
| GSE43470 | RNF183 | 138065 | 4 | 3 | 36 | |
| GSE46452 | RNF183 | 138065 | 6 | 13 | 40 | |
| GSE47630 | RNF183 | 138065 | 3 | 16 | 21 | |
| GSE54993 | RNF183 | 138065 | 3 | 3 | 64 | |
| GSE54994 | RNF183 | 138065 | 9 | 10 | 34 | |
| GSE60625 | RNF183 | 138065 | 0 | 0 | 11 | |
| GSE74703 | RNF183 | 138065 | 4 | 3 | 29 | |
| GSE74704 | RNF183 | 138065 | 2 | 8 | 10 | |
| TCGA | RNF183 | 138065 | 26 | 22 | 48 |
Total number of gains: 65; Total number of losses: 98; Total Number of normals: 325.
Somatic mutations of RNF183:
Generating mutation plots.
Highly correlated genes for RNF183:
Showing top 20/441 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF183 | EPS15 | 0.760198 | 3 | 0 | 3 |
| RNF183 | HLA-DPA1 | 0.75694 | 3 | 0 | 3 |
| RNF183 | G0S2 | 0.747762 | 3 | 0 | 3 |
| RNF183 | VNN2 | 0.745473 | 3 | 0 | 3 |
| RNF183 | ZNF207 | 0.743062 | 3 | 0 | 3 |
| RNF183 | MYL12B | 0.736168 | 3 | 0 | 3 |
| RNF183 | GK | 0.724096 | 3 | 0 | 3 |
| RNF183 | ABI1 | 0.722281 | 3 | 0 | 3 |
| RNF183 | SLC35E3 | 0.722129 | 3 | 0 | 3 |
| RNF183 | BBIP1 | 0.709777 | 3 | 0 | 3 |
| RNF183 | WDFY1 | 0.707455 | 3 | 0 | 3 |
| RNF183 | TBL1Y | 0.705822 | 3 | 0 | 3 |
| RNF183 | NDST2 | 0.702967 | 3 | 0 | 3 |
| RNF183 | ICK | 0.697767 | 3 | 0 | 3 |
| RNF183 | RBAK | 0.693784 | 3 | 0 | 3 |
| RNF183 | BCAS1 | 0.693095 | 5 | 0 | 5 |
| RNF183 | OPHN1 | 0.69221 | 3 | 0 | 3 |
| RNF183 | LETMD1 | 0.690907 | 3 | 0 | 3 |
| RNF183 | RGS10 | 0.690028 | 3 | 0 | 3 |
| RNF183 | E2F8 | 0.689001 | 3 | 0 | 3 |
For details and further investigation, click here
