| Full name: solute carrier family 5 member 1 | Alias Symbol: D22S675|NAGT | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 6523 | HGNC ID: HGNC:11036 | Ensembl Gene: ENSG00000100170 | OMIM ID: 182380 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC5A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC5A1 | 6523 | 242773_at | -0.4890 | 0.3888 | |
| GSE20347 | SLC5A1 | 6523 | 206628_at | -0.8439 | 0.0108 | |
| GSE23400 | SLC5A1 | 6523 | 206628_at | -0.6774 | 0.0000 | |
| GSE26886 | SLC5A1 | 6523 | 206628_at | -2.1727 | 0.0000 | |
| GSE29001 | SLC5A1 | 6523 | 206628_at | -0.8659 | 0.0100 | |
| GSE38129 | SLC5A1 | 6523 | 206628_at | -0.6473 | 0.0116 | |
| GSE45670 | SLC5A1 | 6523 | 206628_at | 0.9691 | 0.0042 | |
| GSE53622 | SLC5A1 | 6523 | 24622 | -1.5730 | 0.0000 | |
| GSE53624 | SLC5A1 | 6523 | 57776 | -1.8424 | 0.0000 | |
| GSE63941 | SLC5A1 | 6523 | 242773_at | 0.1236 | 0.4266 | |
| GSE77861 | SLC5A1 | 6523 | 206628_at | -0.3413 | 0.1802 | |
| GSE97050 | SLC5A1 | 6523 | A_23_P17826 | 0.5243 | 0.2709 | |
| SRP007169 | SLC5A1 | 6523 | RNAseq | -1.9338 | 0.2531 | |
| SRP008496 | SLC5A1 | 6523 | RNAseq | -2.5706 | 0.0099 | |
| SRP064894 | SLC5A1 | 6523 | RNAseq | -2.3541 | 0.0000 | |
| SRP133303 | SLC5A1 | 6523 | RNAseq | -0.9163 | 0.0507 | |
| SRP159526 | SLC5A1 | 6523 | RNAseq | -1.8080 | 0.0083 | |
| SRP193095 | SLC5A1 | 6523 | RNAseq | -1.7906 | 0.0000 | |
| SRP219564 | SLC5A1 | 6523 | RNAseq | -2.1459 | 0.0588 | |
| TCGA | SLC5A1 | 6523 | RNAseq | 0.1740 | 0.6559 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by SLC5A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC5A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC5A1 | 6523 | 4 | 4 | 22 | |
| GSE20123 | SLC5A1 | 6523 | 4 | 3 | 23 | |
| GSE43470 | SLC5A1 | 6523 | 4 | 5 | 34 | |
| GSE46452 | SLC5A1 | 6523 | 31 | 1 | 27 | |
| GSE47630 | SLC5A1 | 6523 | 8 | 5 | 27 | |
| GSE54993 | SLC5A1 | 6523 | 3 | 6 | 61 | |
| GSE54994 | SLC5A1 | 6523 | 9 | 9 | 35 | |
| GSE60625 | SLC5A1 | 6523 | 5 | 0 | 6 | |
| GSE74703 | SLC5A1 | 6523 | 4 | 5 | 27 | |
| GSE74704 | SLC5A1 | 6523 | 1 | 1 | 18 | |
| TCGA | SLC5A1 | 6523 | 27 | 15 | 54 |
Total number of gains: 100; Total number of losses: 54; Total Number of normals: 334.
Somatic mutations of SLC5A1:
Generating mutation plots.
Highly correlated genes for SLC5A1:
Showing top 20/1023 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC5A1 | TGM1 | 0.730596 | 11 | 0 | 11 |
| SLC5A1 | RDH12 | 0.726224 | 7 | 0 | 6 |
| SLC5A1 | SPRR2D | 0.725324 | 4 | 0 | 4 |
| SLC5A1 | SPRR2E | 0.723097 | 4 | 0 | 4 |
| SLC5A1 | MUC15 | 0.718433 | 5 | 0 | 5 |
| SLC5A1 | MAB21L3 | 0.71669 | 4 | 0 | 4 |
| SLC5A1 | TMEM45B | 0.716067 | 7 | 0 | 5 |
| SLC5A1 | CAPN14 | 0.711844 | 5 | 0 | 5 |
| SLC5A1 | TMPRSS11D | 0.711062 | 10 | 0 | 10 |
| SLC5A1 | DEGS2 | 0.710511 | 6 | 0 | 6 |
| SLC5A1 | KLK7 | 0.709741 | 12 | 0 | 11 |
| SLC5A1 | VSIG10L | 0.709539 | 6 | 0 | 6 |
| SLC5A1 | RASAL1 | 0.709259 | 11 | 0 | 10 |
| SLC5A1 | TMEM79 | 0.705246 | 7 | 0 | 7 |
| SLC5A1 | KRT80 | 0.704874 | 7 | 0 | 7 |
| SLC5A1 | SH3PXD2A-AS1 | 0.704802 | 3 | 0 | 3 |
| SLC5A1 | CXCL17 | 0.704704 | 5 | 0 | 5 |
| SLC5A1 | CNFN | 0.703782 | 7 | 0 | 6 |
| SLC5A1 | CRCT1 | 0.702701 | 11 | 0 | 10 |
| SLC5A1 | CYSRT1 | 0.702375 | 5 | 0 | 4 |
For details and further investigation, click here
