GALR2

 

Full name: galanin receptor 2 Alias Symbol: GALNR2
Type: protein-coding gene Cytoband: 17q25.1
Entrez ID: 8811 HGNC ID: HGNC:4133 Ensembl Gene: ENSG00000182687 OMIM ID: 603691
Drug and gene relationship at DGIdb

 

Expression of GALR2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GALR2 8811 211226_at -0.0897 0.8100
GSE20347 GALR2 8811 211226_at -0.0928 0.1440
GSE23400 GALR2 8811 211226_at -0.0903 0.0020
GSE26886 GALR2 8811 211226_at -0.0514 0.7515
GSE29001 GALR2 8811 211226_at -0.0786 0.6573
GSE38129 GALR2 8811 211226_at -0.0210 0.8186
GSE45670 GALR2 8811 211226_at 0.0455 0.7522
GSE53622 GALR2 8811 57201 0.5037 0.0004
GSE53624 GALR2 8811 57201 0.3469 0.0004
GSE63941 GALR2 8811 211226_at 0.2064 0.6618
GSE77861 GALR2 8811 211226_at -0.1194 0.2828
GSE97050 GALR2 8811 A_23_P77756 -0.1033 0.7279
TCGA GALR2 8811 RNAseq 1.3628 0.0030

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by GALR2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GALR2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GALR2 8811 7 2 21
GSE20123 GALR2 8811 7 2 21
GSE43470 GALR2 8811 5 3 35
GSE46452 GALR2 8811 34 0 25
GSE47630 GALR2 8811 8 1 31
GSE54993 GALR2 8811 2 5 63
GSE54994 GALR2 8811 10 4 39
GSE60625 GALR2 8811 6 0 5
GSE74703 GALR2 8811 5 1 30
GSE74704 GALR2 8811 5 1 14
TCGA GALR2 8811 31 10 55

Total number of gains: 120; Total number of losses: 29; Total Number of normals: 339.  


 

Somatic mutations of GALR2:

 

Generating mutation plots.

 

Highly correlated genes for GALR2:

 

Showing top 20/176 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GALR2TBX100.824548303
GALR2CABP70.791099303
GALR2OTOP20.787957303
GALR2KRT350.768997303
GALR2IGSF210.763816303
GALR2KCNT10.747912303
GALR2DRD40.746774303
GALR2ANKRD330.744014303
GALR2NAT8B0.739614303
GALR2DNAH60.73955404
GALR2DUOXA20.722293403
GALR2SEC130.715457303
GALR2VEPH10.713071303
GALR2PNPLA50.712189303
GALR2CDHR50.710932303
GALR2CCDC330.710381303
GALR2SLC25A470.709535403
GALR2FOXO40.702318303
GALR2CA40.697742403
GALR2CPNE90.69649303

For details and further investigation, click here