KRT79

 

Full name: keratin 79 Alias Symbol: K6L|KRT6L
Type: protein-coding gene Cytoband: 12q13.13
Entrez ID: 338785 HGNC ID: HGNC:28930 Ensembl Gene: ENSG00000185640 OMIM ID: 611160
Drug and gene relationship at DGIdb

 

Expression of KRT79:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KRT79 338785 1569909_at 0.1221 0.6894
GSE26886 KRT79 338785 1569909_at 0.0383 0.7913
GSE45670 KRT79 338785 1569909_at -0.0458 0.6552
GSE53622 KRT79 338785 78731 -0.6360 0.0264
GSE53624 KRT79 338785 78731 -1.3335 0.0000
GSE63941 KRT79 338785 1569909_at 0.2056 0.1232
GSE77861 KRT79 338785 1569909_at -0.1649 0.1438
SRP007169 KRT79 338785 RNAseq -4.3032 0.0000
SRP133303 KRT79 338785 RNAseq -2.4546 0.0002
SRP159526 KRT79 338785 RNAseq -2.6958 0.0032
TCGA KRT79 338785 RNAseq 1.1011 0.1346

Upregulated datasets: 0; Downregulated datasets: 4.  


 

Survival by KRT79 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of KRT79:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KRT79 338785 8 1 21
GSE20123 KRT79 338785 8 1 21
GSE43470 KRT79 338785 3 0 40
GSE46452 KRT79 338785 7 1 51
GSE47630 KRT79 338785 10 2 28
GSE54993 KRT79 338785 0 5 65
GSE54994 KRT79 338785 4 1 48
GSE60625 KRT79 338785 0 0 11
GSE74703 KRT79 338785 3 0 33
GSE74704 KRT79 338785 5 1 14
TCGA KRT79 338785 13 11 72

Total number of gains: 61; Total number of losses: 23; Total Number of normals: 404.  


 

Somatic mutations of KRT79:

 

Generating mutation plots.

 

Highly correlated genes for KRT79:

 

Showing top 20/51 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KRT79ZNF2140.699804303
KRT79ZGLP10.647766303
KRT79PSPN0.643923303
KRT79ZFHX20.640067303
KRT79C7orf610.631577303
KRT79VGLL20.628925303
KRT79IZUMO20.610954303
KRT79C11orf940.610098303
KRT79GPR260.609753404
KRT79HAO20.605521303
KRT79FGFR40.604496403
KRT79TMEM151B0.597284303
KRT79NOXA10.594506303
KRT79TUBGCP60.593115303
KRT79HUS1B0.59192303
KRT79TPSG10.590521404
KRT79MYLK20.588833303
KRT79CXCR50.581201303
KRT79ASPG0.578857403
KRT79EGFLAM-AS20.578202303

For details and further investigation, click here