| Full name: persephin | Alias Symbol: PSP | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 5623 | HGNC ID: HGNC:9579 | Ensembl Gene: ENSG00000125650 | OMIM ID: 602921 |
| Drug and gene relationship at DGIdb | |||
Expression of PSPN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSPN | 5623 | 221373_x_at | 0.1333 | 0.5152 | |
| GSE20347 | PSPN | 5623 | 221373_x_at | -0.0783 | 0.2300 | |
| GSE23400 | PSPN | 5623 | 221373_x_at | -0.1054 | 0.0012 | |
| GSE26886 | PSPN | 5623 | 221373_x_at | -0.1420 | 0.3600 | |
| GSE29001 | PSPN | 5623 | 221373_x_at | -0.2246 | 0.0991 | |
| GSE38129 | PSPN | 5623 | 221373_x_at | 0.0122 | 0.8723 | |
| GSE45670 | PSPN | 5623 | 221373_x_at | 0.1361 | 0.1964 | |
| GSE53622 | PSPN | 5623 | 69977 | -0.2753 | 0.0067 | |
| GSE53624 | PSPN | 5623 | 69977 | -0.6483 | 0.0000 | |
| GSE63941 | PSPN | 5623 | 221373_x_at | 0.0796 | 0.6115 | |
| GSE77861 | PSPN | 5623 | 221373_x_at | -0.2151 | 0.1675 | |
| GSE97050 | PSPN | 5623 | A_23_P410507 | -0.3579 | 0.1993 | |
| TCGA | PSPN | 5623 | RNAseq | 0.0204 | 0.9646 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSPN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSPN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSPN | 5623 | 5 | 3 | 22 | |
| GSE20123 | PSPN | 5623 | 4 | 2 | 24 | |
| GSE43470 | PSPN | 5623 | 2 | 6 | 35 | |
| GSE46452 | PSPN | 5623 | 47 | 1 | 11 | |
| GSE47630 | PSPN | 5623 | 5 | 7 | 28 | |
| GSE54993 | PSPN | 5623 | 16 | 3 | 51 | |
| GSE54994 | PSPN | 5623 | 6 | 14 | 33 | |
| GSE60625 | PSPN | 5623 | 9 | 0 | 2 | |
| GSE74703 | PSPN | 5623 | 2 | 4 | 30 | |
| GSE74704 | PSPN | 5623 | 1 | 2 | 17 | |
| TCGA | PSPN | 5623 | 9 | 19 | 68 |
Total number of gains: 106; Total number of losses: 61; Total Number of normals: 321.
Somatic mutations of PSPN:
Generating mutation plots.
Highly correlated genes for PSPN:
Showing top 20/967 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSPN | KRTAP6-1 | 0.845414 | 3 | 0 | 3 |
| PSPN | CLRN2 | 0.812639 | 3 | 0 | 3 |
| PSPN | MRGPRE | 0.807341 | 3 | 0 | 3 |
| PSPN | OR13G1 | 0.807007 | 3 | 0 | 3 |
| PSPN | GRIK4 | 0.796001 | 4 | 0 | 4 |
| PSPN | RAD52 | 0.786895 | 3 | 0 | 3 |
| PSPN | GDF7 | 0.781355 | 3 | 0 | 3 |
| PSPN | CA4 | 0.774497 | 4 | 0 | 4 |
| PSPN | DRG2 | 0.768896 | 3 | 0 | 3 |
| PSPN | SPACA3 | 0.768721 | 4 | 0 | 4 |
| PSPN | SLC25A47 | 0.768191 | 3 | 0 | 3 |
| PSPN | ZBTB45 | 0.767901 | 3 | 0 | 3 |
| PSPN | BARHL2 | 0.755444 | 3 | 0 | 3 |
| PSPN | SALL3 | 0.755193 | 3 | 0 | 3 |
| PSPN | YY2 | 0.75518 | 3 | 0 | 3 |
| PSPN | PGC | 0.754922 | 4 | 0 | 4 |
| PSPN | PRR23B | 0.754032 | 3 | 0 | 3 |
| PSPN | SHISA4 | 0.753718 | 3 | 0 | 3 |
| PSPN | OR4C3 | 0.75209 | 3 | 0 | 3 |
| PSPN | TPRX1 | 0.75193 | 3 | 0 | 3 |
For details and further investigation, click here
