| Full name: asparaginase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 374569 | HGNC ID: HGNC:20123 | Ensembl Gene: ENSG00000166183 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ASPG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASPG | 374569 | 1557226_a_at | -0.3661 | 0.0953 | |
| GSE26886 | ASPG | 374569 | 1557226_a_at | 0.0249 | 0.8666 | |
| GSE45670 | ASPG | 374569 | 1557226_a_at | -0.3554 | 0.0029 | |
| GSE53622 | ASPG | 374569 | 81075 | -2.9000 | 0.0000 | |
| GSE53624 | ASPG | 374569 | 81075 | -3.7958 | 0.0000 | |
| GSE63941 | ASPG | 374569 | 1557226_a_at | -0.0043 | 0.9752 | |
| GSE77861 | ASPG | 374569 | 1557226_a_at | -0.2867 | 0.0264 | |
| GSE97050 | ASPG | 374569 | A_23_P76743 | -0.8936 | 0.1505 | |
| SRP007169 | ASPG | 374569 | RNAseq | -4.4662 | 0.0000 | |
| SRP008496 | ASPG | 374569 | RNAseq | -4.1178 | 0.0000 | |
| SRP064894 | ASPG | 374569 | RNAseq | -2.9233 | 0.0000 | |
| SRP133303 | ASPG | 374569 | RNAseq | -2.5805 | 0.0000 | |
| SRP159526 | ASPG | 374569 | RNAseq | -3.4099 | 0.0000 | |
| SRP193095 | ASPG | 374569 | RNAseq | -2.4111 | 0.0000 | |
| SRP219564 | ASPG | 374569 | RNAseq | -3.6734 | 0.0039 | |
| TCGA | ASPG | 374569 | RNAseq | 0.1722 | 0.7243 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by ASPG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASPG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASPG | 374569 | 12 | 3 | 15 | |
| GSE20123 | ASPG | 374569 | 11 | 2 | 17 | |
| GSE43470 | ASPG | 374569 | 8 | 4 | 31 | |
| GSE46452 | ASPG | 374569 | 19 | 4 | 36 | |
| GSE47630 | ASPG | 374569 | 10 | 8 | 22 | |
| GSE54993 | ASPG | 374569 | 3 | 8 | 59 | |
| GSE54994 | ASPG | 374569 | 21 | 4 | 28 | |
| GSE60625 | ASPG | 374569 | 0 | 2 | 9 | |
| GSE74703 | ASPG | 374569 | 6 | 3 | 27 | |
| GSE74704 | ASPG | 374569 | 5 | 2 | 13 | |
| TCGA | ASPG | 374569 | 31 | 20 | 45 |
Total number of gains: 126; Total number of losses: 60; Total Number of normals: 302.
Somatic mutations of ASPG:
Generating mutation plots.
Highly correlated genes for ASPG:
Showing top 20/1420 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASPG | EPGN | 0.865332 | 3 | 0 | 3 |
| ASPG | MAPK3 | 0.840838 | 6 | 0 | 6 |
| ASPG | ENDOU | 0.825489 | 6 | 0 | 6 |
| ASPG | EHD3 | 0.814354 | 6 | 0 | 6 |
| ASPG | FAM3D | 0.812488 | 6 | 0 | 6 |
| ASPG | HCG22 | 0.81158 | 5 | 0 | 5 |
| ASPG | CYSRT1 | 0.811034 | 5 | 0 | 5 |
| ASPG | TTC9 | 0.807775 | 6 | 0 | 6 |
| ASPG | TP53I3 | 0.807278 | 6 | 0 | 6 |
| ASPG | AGFG2 | 0.799896 | 6 | 0 | 6 |
| ASPG | CAST | 0.798202 | 6 | 0 | 6 |
| ASPG | TRIP10 | 0.796275 | 6 | 0 | 6 |
| ASPG | MPZL3 | 0.794766 | 6 | 0 | 6 |
| ASPG | ANXA9 | 0.794209 | 6 | 0 | 6 |
| ASPG | SLC16A6 | 0.793981 | 6 | 0 | 6 |
| ASPG | GYS2 | 0.792308 | 5 | 0 | 5 |
| ASPG | EPS8L2 | 0.792112 | 5 | 0 | 5 |
| ASPG | VAT1 | 0.790767 | 6 | 0 | 6 |
| ASPG | BARX2 | 0.790292 | 6 | 0 | 6 |
| ASPG | TCP11L2 | 0.790094 | 5 | 0 | 5 |
For details and further investigation, click here
