| Full name: tryptase gamma 1 | Alias Symbol: TMT|PRSS31 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 25823 | HGNC ID: HGNC:14134 | Ensembl Gene: ENSG00000116176 | OMIM ID: 609341 |
| Drug and gene relationship at DGIdb | |||
Expression of TPSG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TPSG1 | 25823 | 220339_s_at | 0.0253 | 0.9367 | |
| GSE20347 | TPSG1 | 25823 | 220339_s_at | -0.1165 | 0.1659 | |
| GSE23400 | TPSG1 | 25823 | 220339_s_at | -0.2081 | 0.0000 | |
| GSE26886 | TPSG1 | 25823 | 220339_s_at | -0.0369 | 0.8425 | |
| GSE29001 | TPSG1 | 25823 | 220339_s_at | -0.3625 | 0.0763 | |
| GSE38129 | TPSG1 | 25823 | 220339_s_at | -0.1402 | 0.0612 | |
| GSE45670 | TPSG1 | 25823 | 220339_s_at | 0.0265 | 0.7956 | |
| GSE63941 | TPSG1 | 25823 | 220339_s_at | 0.1874 | 0.3234 | |
| GSE77861 | TPSG1 | 25823 | 220339_s_at | -0.0718 | 0.5174 | |
| GSE97050 | TPSG1 | 25823 | A_23_P26294 | -0.2302 | 0.4925 | |
| TCGA | TPSG1 | 25823 | RNAseq | -3.1872 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TPSG1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TPSG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPSG1 | 25823 | 5 | 5 | 20 | |
| GSE20123 | TPSG1 | 25823 | 5 | 4 | 21 | |
| GSE43470 | TPSG1 | 25823 | 4 | 7 | 32 | |
| GSE46452 | TPSG1 | 25823 | 38 | 1 | 20 | |
| GSE47630 | TPSG1 | 25823 | 13 | 6 | 21 | |
| GSE54993 | TPSG1 | 25823 | 3 | 5 | 62 | |
| GSE54994 | TPSG1 | 25823 | 5 | 9 | 39 | |
| GSE60625 | TPSG1 | 25823 | 4 | 0 | 7 | |
| GSE74703 | TPSG1 | 25823 | 4 | 5 | 27 | |
| GSE74704 | TPSG1 | 25823 | 3 | 2 | 15 | |
| TCGA | TPSG1 | 25823 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of TPSG1:
Generating mutation plots.
Highly correlated genes for TPSG1:
Showing top 20/1063 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPSG1 | ZBTB22 | 0.794584 | 3 | 0 | 3 |
| TPSG1 | ZNF358 | 0.768272 | 3 | 0 | 3 |
| TPSG1 | RARA | 0.764126 | 4 | 0 | 4 |
| TPSG1 | TCF25 | 0.747268 | 3 | 0 | 3 |
| TPSG1 | KIR2DS5 | 0.730694 | 5 | 0 | 5 |
| TPSG1 | CTF1 | 0.730577 | 3 | 0 | 3 |
| TPSG1 | ARRB1 | 0.721867 | 5 | 0 | 5 |
| TPSG1 | SGCA | 0.720676 | 4 | 0 | 3 |
| TPSG1 | ADPRH | 0.71872 | 5 | 0 | 5 |
| TPSG1 | OPHN1 | 0.717879 | 5 | 0 | 5 |
| TPSG1 | CD36 | 0.714243 | 3 | 0 | 3 |
| TPSG1 | MAN1C1 | 0.708861 | 3 | 0 | 3 |
| TPSG1 | PRELP | 0.708248 | 4 | 0 | 4 |
| TPSG1 | FLYWCH2 | 0.708195 | 3 | 0 | 3 |
| TPSG1 | PGR | 0.703077 | 3 | 0 | 3 |
| TPSG1 | SETD5 | 0.699912 | 3 | 0 | 3 |
| TPSG1 | GH2 | 0.698743 | 6 | 0 | 6 |
| TPSG1 | SCNN1G | 0.698249 | 5 | 0 | 5 |
| TPSG1 | CASC17 | 0.69749 | 3 | 0 | 3 |
| TPSG1 | NR0B2 | 0.694966 | 5 | 0 | 5 |
For details and further investigation, click here
