| Full name: tubulin gamma complex associated protein 6 | Alias Symbol: GCP6|KIAA1669|DJ402G11.6 | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 85378 | HGNC ID: HGNC:18127 | Ensembl Gene: ENSG00000128159 | OMIM ID: 610053 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TUBGCP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBGCP6 | 85378 | 225758_s_at | 0.2651 | 0.7093 | |
| GSE26886 | TUBGCP6 | 85378 | 234308_at | -0.0097 | 0.9533 | |
| GSE45670 | TUBGCP6 | 85378 | 225758_s_at | 0.1904 | 0.1039 | |
| GSE53622 | TUBGCP6 | 85378 | 91914 | 0.0039 | 0.9549 | |
| GSE53624 | TUBGCP6 | 85378 | 91914 | -0.0523 | 0.5218 | |
| GSE63941 | TUBGCP6 | 85378 | 234308_at | -0.1161 | 0.5029 | |
| GSE77861 | TUBGCP6 | 85378 | 234308_at | -0.0894 | 0.3617 | |
| GSE97050 | TUBGCP6 | 85378 | A_23_P6546 | -0.0369 | 0.8793 | |
| SRP007169 | TUBGCP6 | 85378 | RNAseq | 0.9454 | 0.0835 | |
| SRP008496 | TUBGCP6 | 85378 | RNAseq | 1.0008 | 0.0088 | |
| SRP064894 | TUBGCP6 | 85378 | RNAseq | 0.5601 | 0.0169 | |
| SRP133303 | TUBGCP6 | 85378 | RNAseq | -0.1742 | 0.1309 | |
| SRP159526 | TUBGCP6 | 85378 | RNAseq | 0.0982 | 0.7439 | |
| SRP193095 | TUBGCP6 | 85378 | RNAseq | 0.3143 | 0.0505 | |
| SRP219564 | TUBGCP6 | 85378 | RNAseq | 0.0710 | 0.7706 | |
| TCGA | TUBGCP6 | 85378 | RNAseq | -0.1383 | 0.0037 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TUBGCP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TUBGCP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBGCP6 | 85378 | 3 | 8 | 19 | |
| GSE20123 | TUBGCP6 | 85378 | 3 | 8 | 19 | |
| GSE43470 | TUBGCP6 | 85378 | 2 | 8 | 33 | |
| GSE46452 | TUBGCP6 | 85378 | 31 | 2 | 26 | |
| GSE47630 | TUBGCP6 | 85378 | 9 | 4 | 27 | |
| GSE54993 | TUBGCP6 | 85378 | 4 | 6 | 60 | |
| GSE54994 | TUBGCP6 | 85378 | 11 | 8 | 34 | |
| GSE60625 | TUBGCP6 | 85378 | 5 | 0 | 6 | |
| GSE74703 | TUBGCP6 | 85378 | 2 | 6 | 28 | |
| GSE74704 | TUBGCP6 | 85378 | 1 | 4 | 15 | |
| TCGA | TUBGCP6 | 85378 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of TUBGCP6:
Generating mutation plots.
Highly correlated genes for TUBGCP6:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBGCP6 | NKPD1 | 0.768177 | 3 | 0 | 3 |
| TUBGCP6 | DPEP3 | 0.754684 | 3 | 0 | 3 |
| TUBGCP6 | ABCA7 | 0.718971 | 4 | 0 | 4 |
| TUBGCP6 | LEP | 0.717707 | 4 | 0 | 3 |
| TUBGCP6 | HTR6 | 0.706669 | 3 | 0 | 3 |
| TUBGCP6 | NTRK1 | 0.706312 | 3 | 0 | 3 |
| TUBGCP6 | AGAP2 | 0.706127 | 3 | 0 | 3 |
| TUBGCP6 | TNFRSF25 | 0.698632 | 3 | 0 | 3 |
| TUBGCP6 | ZGLP1 | 0.688312 | 3 | 0 | 3 |
| TUBGCP6 | CUL9 | 0.674433 | 4 | 0 | 3 |
| TUBGCP6 | DBF4B | 0.668416 | 3 | 0 | 3 |
| TUBGCP6 | TAZ | 0.666854 | 3 | 0 | 3 |
| TUBGCP6 | CEMP1 | 0.666347 | 3 | 0 | 3 |
| TUBGCP6 | QRICH2 | 0.665927 | 3 | 0 | 3 |
| TUBGCP6 | NOXA1 | 0.663146 | 3 | 0 | 3 |
| TUBGCP6 | SPTBN5 | 0.658758 | 3 | 0 | 3 |
| TUBGCP6 | TUT1 | 0.656557 | 3 | 0 | 3 |
| TUBGCP6 | MEP1A | 0.653234 | 3 | 0 | 3 |
| TUBGCP6 | SYNGAP1 | 0.653151 | 4 | 0 | 3 |
| TUBGCP6 | PML | 0.645863 | 3 | 0 | 3 |
For details and further investigation, click here
