| Full name: NADPH oxidase activator 1 | Alias Symbol: NY-CO-31|FLJ25475 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 10811 | HGNC ID: HGNC:10668 | Ensembl Gene: ENSG00000188747 | OMIM ID: 611255 |
| Drug and gene relationship at DGIdb | |||
Expression of NOXA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOXA1 | 10811 | 232373_at | -0.2703 | 0.2488 | |
| GSE26886 | NOXA1 | 10811 | 232373_at | 0.2097 | 0.1035 | |
| GSE45670 | NOXA1 | 10811 | 232373_at | -0.1653 | 0.1156 | |
| GSE53622 | NOXA1 | 10811 | 51331 | -0.3918 | 0.0000 | |
| GSE53624 | NOXA1 | 10811 | 51331 | -0.4477 | 0.0000 | |
| GSE63941 | NOXA1 | 10811 | 232373_at | 0.8466 | 0.0002 | |
| GSE77861 | NOXA1 | 10811 | 232373_at | -0.2386 | 0.2836 | |
| GSE97050 | NOXA1 | 10811 | A_23_P254353 | -0.1892 | 0.4911 | |
| SRP007169 | NOXA1 | 10811 | RNAseq | -1.6599 | 0.0063 | |
| SRP064894 | NOXA1 | 10811 | RNAseq | -0.6641 | 0.0783 | |
| SRP133303 | NOXA1 | 10811 | RNAseq | -1.3021 | 0.0000 | |
| SRP159526 | NOXA1 | 10811 | RNAseq | -0.5154 | 0.1593 | |
| SRP193095 | NOXA1 | 10811 | RNAseq | -0.6802 | 0.0104 | |
| SRP219564 | NOXA1 | 10811 | RNAseq | -0.6353 | 0.1881 | |
| TCGA | NOXA1 | 10811 | RNAseq | -0.5195 | 0.0084 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NOXA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOXA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOXA1 | 10811 | 5 | 7 | 18 | |
| GSE20123 | NOXA1 | 10811 | 5 | 7 | 18 | |
| GSE43470 | NOXA1 | 10811 | 3 | 7 | 33 | |
| GSE46452 | NOXA1 | 10811 | 6 | 13 | 40 | |
| GSE47630 | NOXA1 | 10811 | 6 | 15 | 19 | |
| GSE54993 | NOXA1 | 10811 | 3 | 3 | 64 | |
| GSE54994 | NOXA1 | 10811 | 19 | 3 | 31 | |
| GSE60625 | NOXA1 | 10811 | 0 | 0 | 11 | |
| GSE74703 | NOXA1 | 10811 | 3 | 5 | 28 | |
| GSE74704 | NOXA1 | 10811 | 3 | 5 | 12 | |
| TCGA | NOXA1 | 10811 | 30 | 23 | 43 |
Total number of gains: 83; Total number of losses: 88; Total Number of normals: 317.
Somatic mutations of NOXA1:
Generating mutation plots.
Highly correlated genes for NOXA1:
Showing top 20/527 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOXA1 | AMN | 0.78804 | 3 | 0 | 3 |
| NOXA1 | TTLL9 | 0.780274 | 3 | 0 | 3 |
| NOXA1 | NKAIN4 | 0.773048 | 3 | 0 | 3 |
| NOXA1 | SNTG2 | 0.759435 | 3 | 0 | 3 |
| NOXA1 | SPRED3 | 0.753801 | 3 | 0 | 3 |
| NOXA1 | FAM131A | 0.753119 | 3 | 0 | 3 |
| NOXA1 | GDF7 | 0.749788 | 3 | 0 | 3 |
| NOXA1 | ENTPD8 | 0.748246 | 3 | 0 | 3 |
| NOXA1 | PHF21A | 0.742575 | 3 | 0 | 3 |
| NOXA1 | IGSF9B | 0.741476 | 3 | 0 | 3 |
| NOXA1 | AGER | 0.739569 | 4 | 0 | 4 |
| NOXA1 | EVX1 | 0.73784 | 5 | 0 | 5 |
| NOXA1 | SYCE3 | 0.736657 | 3 | 0 | 3 |
| NOXA1 | L3MBTL1 | 0.735624 | 3 | 0 | 3 |
| NOXA1 | APOC2 | 0.732732 | 3 | 0 | 3 |
| NOXA1 | MYO18B | 0.72893 | 3 | 0 | 3 |
| NOXA1 | LIM2 | 0.720595 | 3 | 0 | 3 |
| NOXA1 | ZMYND10 | 0.718306 | 4 | 0 | 4 |
| NOXA1 | FAM99B | 0.716642 | 3 | 0 | 3 |
| NOXA1 | CDH23 | 0.711915 | 4 | 0 | 3 |
For details and further investigation, click here
