| Full name: keratin associated protein 10-3 | Alias Symbol: KAP10.3|KAP18.3 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 386682 | HGNC ID: HGNC:22968 | Ensembl Gene: ENSG00000212935 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KRTAP10-3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | KRTAP10-3 | 386682 | 117510 | 0.0802 | 0.3956 | |
| GSE53624 | KRTAP10-3 | 386682 | 117510 | 0.0119 | 0.9153 | |
| GSE97050 | KRTAP10-3 | 386682 | A_33_P3293785 | -0.0346 | 0.9019 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRTAP10-3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP10-3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP10-3 | 386682 | 2 | 8 | 20 | |
| GSE20123 | KRTAP10-3 | 386682 | 2 | 8 | 20 | |
| GSE43470 | KRTAP10-3 | 386682 | 0 | 13 | 30 | |
| GSE46452 | KRTAP10-3 | 386682 | 1 | 21 | 37 | |
| GSE47630 | KRTAP10-3 | 386682 | 6 | 17 | 17 | |
| GSE54993 | KRTAP10-3 | 386682 | 8 | 1 | 61 | |
| GSE54994 | KRTAP10-3 | 386682 | 4 | 8 | 41 | |
| GSE60625 | KRTAP10-3 | 386682 | 0 | 0 | 11 | |
| GSE74703 | KRTAP10-3 | 386682 | 0 | 10 | 26 | |
| GSE74704 | KRTAP10-3 | 386682 | 1 | 4 | 15 |
Total number of gains: 24; Total number of losses: 90; Total Number of normals: 278.
Somatic mutations of KRTAP10-3:
Generating mutation plots.
Highly correlated genes for KRTAP10-3:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP10-3 | KRTAP10-9 | 0.821092 | 3 | 0 | 3 |
| KRTAP10-3 | AK1 | 0.795045 | 3 | 0 | 3 |
| KRTAP10-3 | RAPGEF3 | 0.78454 | 3 | 0 | 3 |
| KRTAP10-3 | SLAMF9 | 0.739865 | 3 | 0 | 3 |
| KRTAP10-3 | VWA5B1 | 0.739082 | 3 | 0 | 3 |
| KRTAP10-3 | SIRPB1 | 0.738445 | 3 | 0 | 3 |
| KRTAP10-3 | NCKAP5L | 0.733607 | 3 | 0 | 3 |
| KRTAP10-3 | CCDC154 | 0.732347 | 3 | 0 | 3 |
| KRTAP10-3 | ADAMTSL2 | 0.714521 | 3 | 0 | 3 |
| KRTAP10-3 | RAX2 | 0.713283 | 3 | 0 | 3 |
| KRTAP10-3 | KRTAP10-1 | 0.710288 | 3 | 0 | 3 |
| KRTAP10-3 | WDR87 | 0.707429 | 3 | 0 | 3 |
| KRTAP10-3 | SEZ6 | 0.695855 | 4 | 0 | 4 |
| KRTAP10-3 | OR1L6 | 0.695562 | 3 | 0 | 3 |
| KRTAP10-3 | HES6 | 0.688821 | 3 | 0 | 3 |
| KRTAP10-3 | MDH1B | 0.683857 | 3 | 0 | 3 |
| KRTAP10-3 | MARK4 | 0.677854 | 3 | 0 | 3 |
| KRTAP10-3 | KRTAP4-7 | 0.675449 | 3 | 0 | 3 |
| KRTAP10-3 | C16orf86 | 0.675236 | 3 | 0 | 3 |
| KRTAP10-3 | ZSCAN30 | 0.67518 | 3 | 0 | 3 |
For details and further investigation, click here
