| Full name: NCK associated protein 5 like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 57701 | HGNC ID: HGNC:29321 | Ensembl Gene: ENSG00000167566 | OMIM ID: 615104 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NCKAP5L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCKAP5L | 57701 | 231865_at | 0.0298 | 0.9454 | |
| GSE26886 | NCKAP5L | 57701 | 231865_at | 0.2765 | 0.0022 | |
| GSE45670 | NCKAP5L | 57701 | 231865_at | -0.1027 | 0.2134 | |
| GSE53622 | NCKAP5L | 57701 | 126486 | 0.1360 | 0.0430 | |
| GSE53624 | NCKAP5L | 57701 | 126486 | -0.1413 | 0.0257 | |
| GSE63941 | NCKAP5L | 57701 | 231865_at | 0.5152 | 0.0610 | |
| GSE77861 | NCKAP5L | 57701 | 231865_at | -0.0146 | 0.9575 | |
| GSE97050 | NCKAP5L | 57701 | A_24_P177964 | -0.2002 | 0.3094 | |
| SRP007169 | NCKAP5L | 57701 | RNAseq | 1.0699 | 0.0536 | |
| SRP008496 | NCKAP5L | 57701 | RNAseq | 1.2390 | 0.0027 | |
| SRP064894 | NCKAP5L | 57701 | RNAseq | 0.6346 | 0.0007 | |
| SRP133303 | NCKAP5L | 57701 | RNAseq | 0.4199 | 0.0763 | |
| SRP159526 | NCKAP5L | 57701 | RNAseq | 0.3516 | 0.3932 | |
| SRP193095 | NCKAP5L | 57701 | RNAseq | 0.9925 | 0.0000 | |
| SRP219564 | NCKAP5L | 57701 | RNAseq | 0.5915 | 0.0506 | |
| TCGA | NCKAP5L | 57701 | RNAseq | 0.0625 | 0.3251 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NCKAP5L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCKAP5L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCKAP5L | 57701 | 7 | 1 | 22 | |
| GSE20123 | NCKAP5L | 57701 | 7 | 1 | 22 | |
| GSE43470 | NCKAP5L | 57701 | 3 | 0 | 40 | |
| GSE46452 | NCKAP5L | 57701 | 8 | 1 | 50 | |
| GSE47630 | NCKAP5L | 57701 | 11 | 2 | 27 | |
| GSE54993 | NCKAP5L | 57701 | 0 | 5 | 65 | |
| GSE54994 | NCKAP5L | 57701 | 4 | 1 | 48 | |
| GSE60625 | NCKAP5L | 57701 | 0 | 0 | 11 | |
| GSE74703 | NCKAP5L | 57701 | 3 | 0 | 33 | |
| GSE74704 | NCKAP5L | 57701 | 5 | 1 | 14 | |
| TCGA | NCKAP5L | 57701 | 15 | 11 | 70 |
Total number of gains: 63; Total number of losses: 23; Total Number of normals: 402.
Somatic mutations of NCKAP5L:
Generating mutation plots.
Highly correlated genes for NCKAP5L:
Showing top 20/311 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCKAP5L | KRTAP10-3 | 0.733607 | 3 | 0 | 3 |
| NCKAP5L | TFE3 | 0.716678 | 4 | 0 | 4 |
| NCKAP5L | KRTAP10-9 | 0.698215 | 3 | 0 | 3 |
| NCKAP5L | KCNF1 | 0.687961 | 4 | 0 | 4 |
| NCKAP5L | MLXIPL | 0.684623 | 3 | 0 | 3 |
| NCKAP5L | TNNI1 | 0.683262 | 4 | 0 | 4 |
| NCKAP5L | SORCS3 | 0.68237 | 3 | 0 | 3 |
| NCKAP5L | TAOK2 | 0.680731 | 3 | 0 | 3 |
| NCKAP5L | F2RL3 | 0.680621 | 3 | 0 | 3 |
| NCKAP5L | RHAG | 0.678829 | 3 | 0 | 3 |
| NCKAP5L | ZNF428 | 0.678578 | 3 | 0 | 3 |
| NCKAP5L | GJD4 | 0.678287 | 4 | 0 | 4 |
| NCKAP5L | USP2-AS1 | 0.676624 | 3 | 0 | 3 |
| NCKAP5L | SHISA8 | 0.658304 | 4 | 0 | 3 |
| NCKAP5L | CCDC151 | 0.657545 | 3 | 0 | 3 |
| NCKAP5L | EXOG | 0.656069 | 3 | 0 | 3 |
| NCKAP5L | SIGLEC11 | 0.65533 | 3 | 0 | 3 |
| NCKAP5L | ANKRD53 | 0.647869 | 6 | 0 | 5 |
| NCKAP5L | TNFAIP8L1 | 0.647667 | 3 | 0 | 3 |
| NCKAP5L | FOXP3 | 0.646514 | 4 | 0 | 4 |
For details and further investigation, click here
