| Full name: hes family bHLH transcription factor 6 | Alias Symbol: bHLHb41 | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 55502 | HGNC ID: HGNC:18254 | Ensembl Gene: ENSG00000144485 | OMIM ID: 610331 |
| Drug and gene relationship at DGIdb | |||
Expression of HES6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HES6 | 55502 | 226446_at | 1.0684 | 0.2712 | |
| GSE26886 | HES6 | 55502 | 226446_at | 0.7219 | 0.0005 | |
| GSE45670 | HES6 | 55502 | 226446_at | 0.6944 | 0.0944 | |
| GSE53622 | HES6 | 55502 | 28109 | 0.1963 | 0.0008 | |
| GSE53624 | HES6 | 55502 | 28109 | 0.0076 | 0.9242 | |
| GSE63941 | HES6 | 55502 | 226446_at | 0.7442 | 0.2744 | |
| GSE77861 | HES6 | 55502 | 226446_at | 0.3320 | 0.0415 | |
| GSE97050 | HES6 | 55502 | A_33_P3322859 | 0.0150 | 0.9633 | |
| SRP007169 | HES6 | 55502 | RNAseq | 2.2898 | 0.0112 | |
| SRP064894 | HES6 | 55502 | RNAseq | 1.1502 | 0.0006 | |
| SRP133303 | HES6 | 55502 | RNAseq | 2.1180 | 0.0001 | |
| SRP159526 | HES6 | 55502 | RNAseq | 2.3665 | 0.0000 | |
| SRP219564 | HES6 | 55502 | RNAseq | 1.0191 | 0.1580 | |
| TCGA | HES6 | 55502 | RNAseq | -0.0860 | 0.5965 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by HES6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HES6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HES6 | 55502 | 1 | 12 | 17 | |
| GSE20123 | HES6 | 55502 | 1 | 12 | 17 | |
| GSE43470 | HES6 | 55502 | 1 | 9 | 33 | |
| GSE46452 | HES6 | 55502 | 0 | 5 | 54 | |
| GSE47630 | HES6 | 55502 | 4 | 5 | 31 | |
| GSE54993 | HES6 | 55502 | 3 | 2 | 65 | |
| GSE54994 | HES6 | 55502 | 8 | 9 | 36 | |
| GSE60625 | HES6 | 55502 | 0 | 3 | 8 | |
| GSE74703 | HES6 | 55502 | 1 | 7 | 28 | |
| GSE74704 | HES6 | 55502 | 1 | 5 | 14 | |
| TCGA | HES6 | 55502 | 12 | 27 | 57 |
Total number of gains: 32; Total number of losses: 96; Total Number of normals: 360.
Somatic mutations of HES6:
Generating mutation plots.
Highly correlated genes for HES6:
Showing top 20/499 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HES6 | SFTPA2 | 0.760853 | 3 | 0 | 3 |
| HES6 | ALG12 | 0.760167 | 4 | 0 | 4 |
| HES6 | NOP14-AS1 | 0.758299 | 3 | 0 | 3 |
| HES6 | CDH24 | 0.756737 | 5 | 0 | 5 |
| HES6 | OR2T12 | 0.752726 | 3 | 0 | 3 |
| HES6 | GPC1 | 0.747866 | 4 | 0 | 4 |
| HES6 | KRTAP10-9 | 0.739719 | 3 | 0 | 3 |
| HES6 | MRPS5 | 0.734905 | 3 | 0 | 3 |
| HES6 | CAMTA2 | 0.73428 | 3 | 0 | 3 |
| HES6 | APBB2 | 0.732813 | 3 | 0 | 3 |
| HES6 | ENTPD2 | 0.730875 | 5 | 0 | 5 |
| HES6 | SPEG | 0.729848 | 3 | 0 | 3 |
| HES6 | KNOP1 | 0.72854 | 3 | 0 | 3 |
| HES6 | SLC13A2 | 0.727926 | 3 | 0 | 3 |
| HES6 | SLC26A5 | 0.726127 | 3 | 0 | 3 |
| HES6 | ELFN1 | 0.722708 | 5 | 0 | 4 |
| HES6 | SZT2 | 0.720901 | 3 | 0 | 3 |
| HES6 | NAV1 | 0.717505 | 3 | 0 | 3 |
| HES6 | RBM17 | 0.716986 | 4 | 0 | 4 |
| HES6 | PRRX2 | 0.716736 | 4 | 0 | 4 |
For details and further investigation, click here
