| Full name: ADAMTS like 2 | Alias Symbol: KIAA0605 | ||
| Type: protein-coding gene | Cytoband: 9q34.2 | ||
| Entrez ID: 9719 | HGNC ID: HGNC:14631 | Ensembl Gene: ENSG00000197859 | OMIM ID: 612277 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAMTSL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAMTSL2 | 9719 | 206629_at | 0.2485 | 0.2176 | |
| GSE20347 | ADAMTSL2 | 9719 | 206629_at | 0.0089 | 0.9002 | |
| GSE23400 | ADAMTSL2 | 9719 | 206629_at | -0.1002 | 0.0016 | |
| GSE26886 | ADAMTSL2 | 9719 | 206629_at | 0.5002 | 0.0048 | |
| GSE29001 | ADAMTSL2 | 9719 | 206629_at | 0.0604 | 0.6470 | |
| GSE38129 | ADAMTSL2 | 9719 | 206629_at | 0.0575 | 0.6259 | |
| GSE45670 | ADAMTSL2 | 9719 | 206629_at | 0.0597 | 0.5559 | |
| GSE53622 | ADAMTSL2 | 9719 | 88383 | 0.0109 | 0.8963 | |
| GSE53624 | ADAMTSL2 | 9719 | 88383 | 0.0559 | 0.4879 | |
| GSE63941 | ADAMTSL2 | 9719 | 206629_at | 0.2088 | 0.1413 | |
| GSE77861 | ADAMTSL2 | 9719 | 206629_at | -0.0135 | 0.9432 | |
| GSE97050 | ADAMTSL2 | 9719 | A_33_P3312509 | 0.2140 | 0.3552 | |
| SRP007169 | ADAMTSL2 | 9719 | RNAseq | 1.0620 | 0.2182 | |
| SRP064894 | ADAMTSL2 | 9719 | RNAseq | 0.3802 | 0.1019 | |
| SRP133303 | ADAMTSL2 | 9719 | RNAseq | 0.2904 | 0.1419 | |
| SRP159526 | ADAMTSL2 | 9719 | RNAseq | 0.0006 | 0.9988 | |
| SRP193095 | ADAMTSL2 | 9719 | RNAseq | 0.6123 | 0.0004 | |
| SRP219564 | ADAMTSL2 | 9719 | RNAseq | 0.2731 | 0.5991 | |
| TCGA | ADAMTSL2 | 9719 | RNAseq | 0.1669 | 0.1873 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADAMTSL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAMTSL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAMTSL2 | 9719 | 5 | 7 | 18 | |
| GSE20123 | ADAMTSL2 | 9719 | 5 | 7 | 18 | |
| GSE43470 | ADAMTSL2 | 9719 | 4 | 7 | 32 | |
| GSE46452 | ADAMTSL2 | 9719 | 6 | 13 | 40 | |
| GSE47630 | ADAMTSL2 | 9719 | 4 | 15 | 21 | |
| GSE54993 | ADAMTSL2 | 9719 | 3 | 3 | 64 | |
| GSE54994 | ADAMTSL2 | 9719 | 12 | 9 | 32 | |
| GSE60625 | ADAMTSL2 | 9719 | 0 | 0 | 11 | |
| GSE74703 | ADAMTSL2 | 9719 | 4 | 5 | 27 | |
| GSE74704 | ADAMTSL2 | 9719 | 3 | 5 | 12 | |
| TCGA | ADAMTSL2 | 9719 | 28 | 26 | 42 |
Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.
Somatic mutations of ADAMTSL2:
Generating mutation plots.
Highly correlated genes for ADAMTSL2:
Showing top 20/490 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAMTSL2 | MICALL2 | 0.777085 | 3 | 0 | 3 |
| ADAMTSL2 | PLAUR | 0.756309 | 3 | 0 | 3 |
| ADAMTSL2 | MPZL1 | 0.738271 | 3 | 0 | 3 |
| ADAMTSL2 | ARMC5 | 0.728742 | 4 | 0 | 4 |
| ADAMTSL2 | RBAKDN | 0.724189 | 4 | 0 | 4 |
| ADAMTSL2 | APOBEC3B | 0.72213 | 3 | 0 | 3 |
| ADAMTSL2 | IGF2 | 0.720979 | 3 | 0 | 3 |
| ADAMTSL2 | KRTAP10-3 | 0.714521 | 3 | 0 | 3 |
| ADAMTSL2 | SH3PXD2B | 0.714124 | 3 | 0 | 3 |
| ADAMTSL2 | CACNG7 | 0.704231 | 3 | 0 | 3 |
| ADAMTSL2 | C4orf48 | 0.700416 | 3 | 0 | 3 |
| ADAMTSL2 | VWA5B1 | 0.699812 | 3 | 0 | 3 |
| ADAMTSL2 | TMEM184B | 0.697232 | 4 | 0 | 4 |
| ADAMTSL2 | LIN37 | 0.69364 | 4 | 0 | 4 |
| ADAMTSL2 | KRTAP10-9 | 0.692437 | 3 | 0 | 3 |
| ADAMTSL2 | PLAU | 0.688072 | 3 | 0 | 3 |
| ADAMTSL2 | C11orf42 | 0.686881 | 3 | 0 | 3 |
| ADAMTSL2 | PFN2 | 0.686861 | 3 | 0 | 3 |
| ADAMTSL2 | FAM131A | 0.685772 | 3 | 0 | 3 |
| ADAMTSL2 | LGI2 | 0.685435 | 4 | 0 | 4 |
For details and further investigation, click here
