| Full name: galectin 12 | Alias Symbol: GRIP1 | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 85329 | HGNC ID: HGNC:15788 | Ensembl Gene: ENSG00000133317 | OMIM ID: 606096 |
| Drug and gene relationship at DGIdb | |||
Expression of LGALS12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LGALS12 | 85329 | 223828_s_at | -0.0348 | 0.9325 | |
| GSE26886 | LGALS12 | 85329 | 223828_s_at | 0.0016 | 0.9901 | |
| GSE45670 | LGALS12 | 85329 | 223828_s_at | 0.0690 | 0.5316 | |
| GSE53622 | LGALS12 | 85329 | 48727 | 0.2588 | 0.0054 | |
| GSE53624 | LGALS12 | 85329 | 48727 | 0.1741 | 0.0909 | |
| GSE63941 | LGALS12 | 85329 | 223828_s_at | 0.2316 | 0.1255 | |
| GSE77861 | LGALS12 | 85329 | 223828_s_at | -0.0624 | 0.5451 | |
| GSE97050 | LGALS12 | 85329 | A_23_P139198 | 0.3144 | 0.2657 | |
| SRP133303 | LGALS12 | 85329 | RNAseq | 0.1393 | 0.6471 | |
| TCGA | LGALS12 | 85329 | RNAseq | -1.8451 | 0.0123 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LGALS12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LGALS12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LGALS12 | 85329 | 6 | 4 | 20 | |
| GSE20123 | LGALS12 | 85329 | 6 | 4 | 20 | |
| GSE43470 | LGALS12 | 85329 | 1 | 4 | 38 | |
| GSE46452 | LGALS12 | 85329 | 8 | 4 | 47 | |
| GSE47630 | LGALS12 | 85329 | 3 | 7 | 30 | |
| GSE54993 | LGALS12 | 85329 | 3 | 0 | 67 | |
| GSE54994 | LGALS12 | 85329 | 5 | 5 | 43 | |
| GSE60625 | LGALS12 | 85329 | 0 | 3 | 8 | |
| GSE74703 | LGALS12 | 85329 | 1 | 2 | 33 | |
| GSE74704 | LGALS12 | 85329 | 4 | 3 | 13 | |
| TCGA | LGALS12 | 85329 | 16 | 11 | 69 |
Total number of gains: 53; Total number of losses: 47; Total Number of normals: 388.
Somatic mutations of LGALS12:
Generating mutation plots.
Highly correlated genes for LGALS12:
Showing top 20/507 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LGALS12 | C9orf153 | 0.807393 | 3 | 0 | 3 |
| LGALS12 | PTAFR | 0.792935 | 3 | 0 | 3 |
| LGALS12 | STRC | 0.788935 | 3 | 0 | 3 |
| LGALS12 | SYT1 | 0.770011 | 3 | 0 | 3 |
| LGALS12 | OR2T27 | 0.762927 | 3 | 0 | 3 |
| LGALS12 | C19orf44 | 0.762132 | 3 | 0 | 3 |
| LGALS12 | TCF23 | 0.757676 | 3 | 0 | 3 |
| LGALS12 | C2orf72 | 0.757644 | 4 | 0 | 4 |
| LGALS12 | PLA2G2C | 0.754422 | 3 | 0 | 3 |
| LGALS12 | YY2 | 0.748538 | 3 | 0 | 3 |
| LGALS12 | TMEM229A | 0.744818 | 3 | 0 | 3 |
| LGALS12 | BSX | 0.744523 | 3 | 0 | 3 |
| LGALS12 | MRGPRG | 0.742468 | 3 | 0 | 3 |
| LGALS12 | VEPH1 | 0.740042 | 3 | 0 | 3 |
| LGALS12 | HNF1B | 0.73903 | 3 | 0 | 3 |
| LGALS12 | USP2-AS1 | 0.738564 | 3 | 0 | 3 |
| LGALS12 | CDHR5 | 0.736902 | 4 | 0 | 4 |
| LGALS12 | MUC3A | 0.735203 | 3 | 0 | 3 |
| LGALS12 | CECR9 | 0.73471 | 3 | 0 | 3 |
| LGALS12 | GYPE | 0.733977 | 3 | 0 | 3 |
For details and further investigation, click here
