| Full name: transcription factor 23 | Alias Symbol: OUT|bHLHa24 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 150921 | HGNC ID: HGNC:18602 | Ensembl Gene: ENSG00000163792 | OMIM ID: 609635 |
| Drug and gene relationship at DGIdb | |||
Expression of TCF23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TCF23 | 150921 | 22771 | 0.2493 | 0.0052 | |
| GSE53624 | TCF23 | 150921 | 22771 | 0.1211 | 0.2525 | |
| GSE97050 | TCF23 | 150921 | A_24_P237936 | 0.0067 | 0.9808 | |
| SRP007169 | TCF23 | 150921 | RNAseq | 0.7095 | 0.3897 | |
| SRP133303 | TCF23 | 150921 | RNAseq | 0.1051 | 0.4449 | |
| SRP193095 | TCF23 | 150921 | RNAseq | 0.1865 | 0.2977 | |
| SRP219564 | TCF23 | 150921 | RNAseq | 0.2871 | 0.6037 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TCF23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TCF23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCF23 | 150921 | 11 | 2 | 17 | |
| GSE20123 | TCF23 | 150921 | 11 | 2 | 17 | |
| GSE43470 | TCF23 | 150921 | 3 | 1 | 39 | |
| GSE46452 | TCF23 | 150921 | 3 | 4 | 52 | |
| GSE47630 | TCF23 | 150921 | 8 | 0 | 32 | |
| GSE54993 | TCF23 | 150921 | 0 | 6 | 64 | |
| GSE54994 | TCF23 | 150921 | 10 | 0 | 43 | |
| GSE60625 | TCF23 | 150921 | 0 | 3 | 8 | |
| GSE74703 | TCF23 | 150921 | 3 | 0 | 33 | |
| GSE74704 | TCF23 | 150921 | 9 | 1 | 10 | |
| TCGA | TCF23 | 150921 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of TCF23:
Generating mutation plots.
Highly correlated genes for TCF23:
Showing top 20/65 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCF23 | VWA5B1 | 0.781871 | 3 | 0 | 3 |
| TCF23 | DEFB128 | 0.774033 | 3 | 0 | 3 |
| TCF23 | RAPGEF3 | 0.773642 | 3 | 0 | 3 |
| TCF23 | LGALS12 | 0.757676 | 3 | 0 | 3 |
| TCF23 | OR11A1 | 0.736256 | 3 | 0 | 3 |
| TCF23 | FAM30A | 0.735456 | 3 | 0 | 3 |
| TCF23 | SLAMF9 | 0.735001 | 3 | 0 | 3 |
| TCF23 | SIRPB1 | 0.727092 | 3 | 0 | 3 |
| TCF23 | SLC38A6 | 0.719732 | 3 | 0 | 3 |
| TCF23 | CCDC154 | 0.711902 | 3 | 0 | 3 |
| TCF23 | OR1L6 | 0.708048 | 3 | 0 | 3 |
| TCF23 | ALPI | 0.707479 | 3 | 0 | 3 |
| TCF23 | COL11A2 | 0.702956 | 3 | 0 | 3 |
| TCF23 | UNC5A | 0.701848 | 3 | 0 | 3 |
| TCF23 | ZNF445 | 0.698125 | 3 | 0 | 3 |
| TCF23 | MDH1B | 0.694436 | 3 | 0 | 3 |
| TCF23 | RSPH9 | 0.685416 | 3 | 0 | 3 |
| TCF23 | SPEG | 0.676419 | 4 | 0 | 3 |
| TCF23 | KLF16 | 0.673725 | 3 | 0 | 3 |
| TCF23 | AK1 | 0.670606 | 3 | 0 | 3 |
For details and further investigation, click here
