| Full name: leucine rich repeat neuronal 3 | Alias Symbol: NLRR3|FLJ11129|FIGLER5 | ||
| Type: protein-coding gene | Cytoband: 7q31.1 | ||
| Entrez ID: 54674 | HGNC ID: HGNC:17200 | Ensembl Gene: ENSG00000173114 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRN3 | 54674 | 209841_s_at | -0.6411 | 0.1811 | |
| GSE20347 | LRRN3 | 54674 | 209840_s_at | -0.1649 | 0.2226 | |
| GSE23400 | LRRN3 | 54674 | 209841_s_at | -0.1046 | 0.0002 | |
| GSE26886 | LRRN3 | 54674 | 209841_s_at | -0.1778 | 0.3480 | |
| GSE29001 | LRRN3 | 54674 | 209841_s_at | -0.5161 | 0.0071 | |
| GSE38129 | LRRN3 | 54674 | 209840_s_at | -0.5101 | 0.0041 | |
| GSE45670 | LRRN3 | 54674 | 209841_s_at | -0.7509 | 0.0092 | |
| GSE53622 | LRRN3 | 54674 | 38804 | -0.3901 | 0.0004 | |
| GSE53624 | LRRN3 | 54674 | 38804 | -0.4758 | 0.0000 | |
| GSE63941 | LRRN3 | 54674 | 209841_s_at | -2.1371 | 0.0000 | |
| GSE77861 | LRRN3 | 54674 | 209840_s_at | 0.0084 | 0.9568 | |
| GSE97050 | LRRN3 | 54674 | A_23_P31376 | -0.5101 | 0.4233 | |
| SRP064894 | LRRN3 | 54674 | RNAseq | -0.4114 | 0.4133 | |
| SRP133303 | LRRN3 | 54674 | RNAseq | 0.1816 | 0.4820 | |
| SRP193095 | LRRN3 | 54674 | RNAseq | 0.1370 | 0.3672 | |
| SRP219564 | LRRN3 | 54674 | RNAseq | -1.0167 | 0.0387 | |
| TCGA | LRRN3 | 54674 | RNAseq | -0.2974 | 0.3305 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by LRRN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRN3 | 54674 | 11 | 2 | 17 | |
| GSE20123 | LRRN3 | 54674 | 11 | 2 | 17 | |
| GSE43470 | LRRN3 | 54674 | 7 | 1 | 35 | |
| GSE46452 | LRRN3 | 54674 | 8 | 1 | 50 | |
| GSE47630 | LRRN3 | 54674 | 7 | 4 | 29 | |
| GSE54993 | LRRN3 | 54674 | 3 | 8 | 59 | |
| GSE54994 | LRRN3 | 54674 | 12 | 6 | 35 | |
| GSE60625 | LRRN3 | 54674 | 0 | 0 | 11 | |
| GSE74703 | LRRN3 | 54674 | 7 | 1 | 28 | |
| GSE74704 | LRRN3 | 54674 | 7 | 2 | 11 | |
| TCGA | LRRN3 | 54674 | 34 | 21 | 41 |
Total number of gains: 107; Total number of losses: 48; Total Number of normals: 333.
Somatic mutations of LRRN3:
Generating mutation plots.
Highly correlated genes for LRRN3:
Showing top 20/432 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRN3 | FKBP7 | 0.712855 | 3 | 0 | 3 |
| LRRN3 | LINC01279 | 0.70907 | 3 | 0 | 3 |
| LRRN3 | HEPH | 0.708838 | 4 | 0 | 3 |
| LRRN3 | ZBTB20 | 0.688863 | 5 | 0 | 5 |
| LRRN3 | NEGR1 | 0.687405 | 6 | 0 | 5 |
| LRRN3 | PDZRN3 | 0.68672 | 4 | 0 | 4 |
| LRRN3 | GADL1 | 0.683461 | 3 | 0 | 3 |
| LRRN3 | ADCY5 | 0.669263 | 5 | 0 | 3 |
| LRRN3 | JAZF1 | 0.659518 | 4 | 0 | 4 |
| LRRN3 | ADCYAP1R1 | 0.659049 | 4 | 0 | 3 |
| LRRN3 | GALNT15 | 0.656324 | 4 | 0 | 3 |
| LRRN3 | TMOD2 | 0.654347 | 4 | 0 | 4 |
| LRRN3 | DAAM2 | 0.650088 | 5 | 0 | 4 |
| LRRN3 | DACT3 | 0.649948 | 6 | 0 | 4 |
| LRRN3 | MYOCD | 0.648729 | 5 | 0 | 3 |
| LRRN3 | IL17D | 0.648723 | 5 | 0 | 3 |
| LRRN3 | CCDC69 | 0.648708 | 8 | 0 | 6 |
| LRRN3 | LINC01082 | 0.648466 | 5 | 0 | 3 |
| LRRN3 | FBN1 | 0.643215 | 4 | 0 | 3 |
| LRRN3 | SMIM10 | 0.643016 | 5 | 0 | 4 |
For details and further investigation, click here
