| Full name: zinc finger and BTB domain containing 20 | Alias Symbol: ODA-8S|DKFZp566F123|DPZF | ||
| Type: protein-coding gene | Cytoband: 3q13.31 | ||
| Entrez ID: 26137 | HGNC ID: HGNC:13503 | Ensembl Gene: ENSG00000181722 | OMIM ID: 606025 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZBTB20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB20 | 26137 | 235308_at | -0.8613 | 0.2320 | |
| GSE20347 | ZBTB20 | 26137 | 213158_at | -0.5706 | 0.0525 | |
| GSE23400 | ZBTB20 | 26137 | 205383_s_at | -0.3928 | 0.0017 | |
| GSE26886 | ZBTB20 | 26137 | 205383_s_at | 1.5260 | 0.0003 | |
| GSE29001 | ZBTB20 | 26137 | 205383_s_at | -0.2807 | 0.5469 | |
| GSE38129 | ZBTB20 | 26137 | 213158_at | -1.0412 | 0.0001 | |
| GSE45670 | ZBTB20 | 26137 | 213156_at | -1.5734 | 0.0001 | |
| GSE63941 | ZBTB20 | 26137 | 205383_s_at | -2.7332 | 0.0015 | |
| GSE77861 | ZBTB20 | 26137 | 205383_s_at | 0.2400 | 0.5656 | |
| GSE97050 | ZBTB20 | 26137 | A_23_P40866 | -0.3927 | 0.3051 | |
| SRP007169 | ZBTB20 | 26137 | RNAseq | 0.9831 | 0.0376 | |
| SRP008496 | ZBTB20 | 26137 | RNAseq | 1.5979 | 0.0000 | |
| SRP064894 | ZBTB20 | 26137 | RNAseq | -0.0708 | 0.8017 | |
| SRP133303 | ZBTB20 | 26137 | RNAseq | -0.4582 | 0.0446 | |
| SRP159526 | ZBTB20 | 26137 | RNAseq | -0.5559 | 0.0132 | |
| SRP193095 | ZBTB20 | 26137 | RNAseq | 0.1428 | 0.4358 | |
| SRP219564 | ZBTB20 | 26137 | RNAseq | -0.2137 | 0.7238 | |
| TCGA | ZBTB20 | 26137 | RNAseq | -0.6080 | 0.0001 |
Upregulated datasets: 2; Downregulated datasets: 3.
Survival by ZBTB20 expression:
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| TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB20 | 26137 | 17 | 1 | 12 | |
| GSE20123 | ZBTB20 | 26137 | 17 | 1 | 12 | |
| GSE43470 | ZBTB20 | 26137 | 21 | 1 | 21 | |
| GSE46452 | ZBTB20 | 26137 | 13 | 5 | 41 | |
| GSE47630 | ZBTB20 | 26137 | 16 | 6 | 18 | |
| GSE54993 | ZBTB20 | 26137 | 2 | 6 | 62 | |
| GSE54994 | ZBTB20 | 26137 | 29 | 4 | 20 | |
| GSE60625 | ZBTB20 | 26137 | 0 | 6 | 5 | |
| GSE74703 | ZBTB20 | 26137 | 17 | 1 | 18 | |
| GSE74704 | ZBTB20 | 26137 | 13 | 1 | 6 | |
| TCGA | ZBTB20 | 26137 | 54 | 10 | 32 |
Total number of gains: 199; Total number of losses: 42; Total Number of normals: 247.
Somatic mutations of ZBTB20:
Generating mutation plots.
Highly correlated genes for ZBTB20:
Showing top 20/750 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB20 | CREBRF | 0.797148 | 3 | 0 | 3 |
| ZBTB20 | PNCK | 0.795577 | 3 | 0 | 3 |
| ZBTB20 | PPP1R14A | 0.761846 | 4 | 0 | 4 |
| ZBTB20 | ZFPM2 | 0.75351 | 7 | 0 | 6 |
| ZBTB20 | RGS7BP | 0.751747 | 3 | 0 | 3 |
| ZBTB20 | NEGR1 | 0.750235 | 4 | 0 | 4 |
| ZBTB20 | MAGI2-AS3 | 0.745173 | 4 | 0 | 4 |
| ZBTB20 | ST6GAL2 | 0.742981 | 3 | 0 | 3 |
| ZBTB20 | CELF2 | 0.729918 | 8 | 0 | 7 |
| ZBTB20 | BOC | 0.728882 | 3 | 0 | 3 |
| ZBTB20 | SATB1 | 0.728045 | 6 | 0 | 6 |
| ZBTB20 | TMEM178A | 0.723989 | 3 | 0 | 3 |
| ZBTB20 | FILIP1 | 0.72367 | 4 | 0 | 4 |
| ZBTB20 | ANKDD1A | 0.723571 | 3 | 0 | 3 |
| ZBTB20 | LINC01279 | 0.722331 | 5 | 0 | 5 |
| ZBTB20 | RBPMS2 | 0.722101 | 5 | 0 | 4 |
| ZBTB20 | DACT3 | 0.721859 | 5 | 0 | 5 |
| ZBTB20 | MARVELD1 | 0.721708 | 3 | 0 | 3 |
| ZBTB20 | LINC01082 | 0.720066 | 3 | 0 | 3 |
| ZBTB20 | MIR100HG | 0.719498 | 3 | 0 | 3 |
For details and further investigation, click here
