| Full name: glutamate decarboxylase like 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p24.1-p23 | ||
| Entrez ID: 339896 | HGNC ID: HGNC:27949 | Ensembl Gene: ENSG00000144644 | OMIM ID: 615601 |
| Drug and gene relationship at DGIdb | |||
Expression of GADL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GADL1 | 339896 | 1563533_at | -0.4619 | 0.3540 | |
| GSE26886 | GADL1 | 339896 | 1563533_at | -0.1609 | 0.1227 | |
| GSE45670 | GADL1 | 339896 | 1563533_at | -0.3392 | 0.0500 | |
| GSE53622 | GADL1 | 339896 | 46298 | -0.1360 | 0.6157 | |
| GSE53624 | GADL1 | 339896 | 46298 | -0.0344 | 0.8334 | |
| GSE63941 | GADL1 | 339896 | 1563533_at | -0.0485 | 0.6922 | |
| GSE77861 | GADL1 | 339896 | 1563533_at | -0.2005 | 0.0545 | |
| GSE97050 | GADL1 | 339896 | A_33_P3244793 | -0.2543 | 0.5557 | |
| SRP133303 | GADL1 | 339896 | RNAseq | 0.5727 | 0.0969 | |
| TCGA | GADL1 | 339896 | RNAseq | 3.7050 | 0.0035 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GADL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GADL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GADL1 | 339896 | 0 | 17 | 13 | |
| GSE20123 | GADL1 | 339896 | 0 | 17 | 13 | |
| GSE43470 | GADL1 | 339896 | 0 | 20 | 23 | |
| GSE46452 | GADL1 | 339896 | 2 | 17 | 40 | |
| GSE47630 | GADL1 | 339896 | 1 | 24 | 15 | |
| GSE54993 | GADL1 | 339896 | 6 | 3 | 61 | |
| GSE54994 | GADL1 | 339896 | 1 | 32 | 20 | |
| GSE60625 | GADL1 | 339896 | 5 | 0 | 6 | |
| GSE74703 | GADL1 | 339896 | 0 | 17 | 19 | |
| GSE74704 | GADL1 | 339896 | 0 | 11 | 9 | |
| TCGA | GADL1 | 339896 | 1 | 69 | 26 |
Total number of gains: 16; Total number of losses: 227; Total Number of normals: 245.
Somatic mutations of GADL1:
Generating mutation plots.
Highly correlated genes for GADL1:
Showing top 20/140 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GADL1 | KLHL10 | 0.811709 | 3 | 0 | 3 |
| GADL1 | GPM6A | 0.790932 | 5 | 0 | 5 |
| GADL1 | HECTD2 | 0.742615 | 3 | 0 | 3 |
| GADL1 | PRKACG | 0.704147 | 3 | 0 | 3 |
| GADL1 | LINC00472 | 0.69496 | 4 | 0 | 3 |
| GADL1 | PPP1R1A | 0.693811 | 4 | 0 | 4 |
| GADL1 | LRRN3 | 0.683461 | 3 | 0 | 3 |
| GADL1 | HAND2-AS1 | 0.680968 | 5 | 0 | 5 |
| GADL1 | DHRS12 | 0.66842 | 3 | 0 | 3 |
| GADL1 | NECAB1 | 0.663425 | 4 | 0 | 3 |
| GADL1 | MAPK8IP1 | 0.656119 | 3 | 0 | 3 |
| GADL1 | CACNA1C | 0.654777 | 5 | 0 | 4 |
| GADL1 | INSL3 | 0.65233 | 3 | 0 | 3 |
| GADL1 | TMEM8B | 0.652208 | 4 | 0 | 3 |
| GADL1 | HS6ST3 | 0.650567 | 5 | 0 | 4 |
| GADL1 | POPDC2 | 0.648564 | 5 | 0 | 4 |
| GADL1 | USP2 | 0.647286 | 3 | 0 | 3 |
| GADL1 | PLCB1 | 0.646812 | 3 | 0 | 3 |
| GADL1 | BRINP3 | 0.646422 | 4 | 0 | 3 |
| GADL1 | ADAMTS19 | 0.644302 | 3 | 0 | 3 |
For details and further investigation, click here
