| Full name: scavenger receptor class F member 1 | Alias Symbol: SREC|KIAA0149|SREC1 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 8578 | HGNC ID: HGNC:16820 | Ensembl Gene: ENSG00000074660 | OMIM ID: 607873 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SCARF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCARF1 | 8578 | 1555021_a_at | -0.1052 | 0.7399 | |
| GSE20347 | SCARF1 | 8578 | 206995_x_at | -0.0641 | 0.3254 | |
| GSE23400 | SCARF1 | 8578 | 206995_x_at | -0.0401 | 0.0267 | |
| GSE26886 | SCARF1 | 8578 | 1555021_a_at | -0.1653 | 0.1788 | |
| GSE29001 | SCARF1 | 8578 | 206995_x_at | -0.0575 | 0.7069 | |
| GSE38129 | SCARF1 | 8578 | 206995_x_at | -0.1697 | 0.1903 | |
| GSE45670 | SCARF1 | 8578 | 1555021_a_at | -0.0339 | 0.6764 | |
| GSE53622 | SCARF1 | 8578 | 48784 | -0.1667 | 0.0509 | |
| GSE53624 | SCARF1 | 8578 | 48784 | -0.3229 | 0.0004 | |
| GSE63941 | SCARF1 | 8578 | 1555021_a_at | 0.2446 | 0.1632 | |
| GSE77861 | SCARF1 | 8578 | 1555021_a_at | -0.2945 | 0.0059 | |
| GSE97050 | SCARF1 | 8578 | A_23_P15414 | 0.0543 | 0.8959 | |
| SRP007169 | SCARF1 | 8578 | RNAseq | 1.4963 | 0.0319 | |
| SRP064894 | SCARF1 | 8578 | RNAseq | 0.4938 | 0.0595 | |
| SRP133303 | SCARF1 | 8578 | RNAseq | 0.0070 | 0.9756 | |
| SRP159526 | SCARF1 | 8578 | RNAseq | -0.0983 | 0.6365 | |
| SRP193095 | SCARF1 | 8578 | RNAseq | 0.6916 | 0.0001 | |
| SRP219564 | SCARF1 | 8578 | RNAseq | -0.0785 | 0.8320 | |
| TCGA | SCARF1 | 8578 | RNAseq | -0.3491 | 0.0009 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SCARF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCARF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCARF1 | 8578 | 5 | 2 | 23 | |
| GSE20123 | SCARF1 | 8578 | 5 | 3 | 22 | |
| GSE43470 | SCARF1 | 8578 | 3 | 6 | 34 | |
| GSE46452 | SCARF1 | 8578 | 34 | 1 | 24 | |
| GSE47630 | SCARF1 | 8578 | 8 | 1 | 31 | |
| GSE54993 | SCARF1 | 8578 | 9 | 3 | 58 | |
| GSE54994 | SCARF1 | 8578 | 8 | 8 | 37 | |
| GSE60625 | SCARF1 | 8578 | 4 | 0 | 7 | |
| GSE74703 | SCARF1 | 8578 | 2 | 3 | 31 | |
| GSE74704 | SCARF1 | 8578 | 3 | 1 | 16 | |
| TCGA | SCARF1 | 8578 | 19 | 21 | 56 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of SCARF1:
Generating mutation plots.
Highly correlated genes for SCARF1:
Showing top 20/244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCARF1 | EVC2 | 0.751713 | 3 | 0 | 3 |
| SCARF1 | CLDN2 | 0.733201 | 3 | 0 | 3 |
| SCARF1 | FLT1 | 0.73058 | 3 | 0 | 3 |
| SCARF1 | DNAH7 | 0.727406 | 3 | 0 | 3 |
| SCARF1 | RPL29 | 0.720199 | 3 | 0 | 3 |
| SCARF1 | EXOC3L2 | 0.713226 | 3 | 0 | 3 |
| SCARF1 | PHYHD1 | 0.712844 | 3 | 0 | 3 |
| SCARF1 | MTHFD1L | 0.711701 | 3 | 0 | 3 |
| SCARF1 | PRR29 | 0.706237 | 3 | 0 | 3 |
| SCARF1 | FCGRT | 0.699237 | 3 | 0 | 3 |
| SCARF1 | CD82 | 0.695338 | 3 | 0 | 3 |
| SCARF1 | LPAR6 | 0.691903 | 3 | 0 | 3 |
| SCARF1 | ARRDC3 | 0.690943 | 3 | 0 | 3 |
| SCARF1 | HAS1 | 0.682818 | 3 | 0 | 3 |
| SCARF1 | MS4A4A | 0.676292 | 3 | 0 | 3 |
| SCARF1 | LYPD8 | 0.669573 | 3 | 0 | 3 |
| SCARF1 | SPATA31E1 | 0.668969 | 3 | 0 | 3 |
| SCARF1 | TNFRSF1B | 0.668787 | 4 | 0 | 4 |
| SCARF1 | LMAN2 | 0.66771 | 3 | 0 | 3 |
| SCARF1 | ITGAM | 0.664765 | 3 | 0 | 3 |
For details and further investigation, click here
