MAGEA1

 

Full name: MAGE family member A1 Alias Symbol: MGC9326|CT1.1
Type: protein-coding gene Cytoband: Xq28
Entrez ID: 4100 HGNC ID: HGNC:6796 Ensembl Gene: ENSG00000198681 OMIM ID: 300016
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of MAGEA1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MAGEA1 4100 207325_x_at 0.9989 0.2751
GSE20347 MAGEA1 4100 207325_x_at 1.1924 0.0272
GSE23400 MAGEA1 4100 207325_x_at 0.4321 0.0013
GSE26886 MAGEA1 4100 207325_x_at 1.3638 0.0126
GSE29001 MAGEA1 4100 207325_x_at 1.7925 0.0234
GSE38129 MAGEA1 4100 207325_x_at 1.1443 0.0082
GSE45670 MAGEA1 4100 207325_x_at 2.4210 0.0046
GSE53622 MAGEA1 4100 51338 2.7454 0.0000
GSE53624 MAGEA1 4100 51338 2.9525 0.0000
GSE63941 MAGEA1 4100 207325_x_at 2.3466 0.2676
GSE77861 MAGEA1 4100 207325_x_at 0.8212 0.2962
GSE97050 MAGEA1 4100 A_23_P96291 1.5088 0.1791
TCGA MAGEA1 4100 RNAseq 6.8366 0.0000

Upregulated datasets: 8; Downregulated datasets: 0.  

 

Survival by MAGEA1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MAGEA1:

 

No record found for this gene.

 

Somatic mutations of MAGEA1:

 

Generating mutation plots.

 

Highly correlated genes for MAGEA1:

 

Showing top 20/197 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MAGEA1RNASE100.742418303
MAGEA1MAGEA40.73063613012
MAGEA1MAGEA120.7165311010
MAGEA1POTEM0.707589404
MAGEA1MAGEA60.70301513011
MAGEA1NUP2100.655644403
MAGEA1YES10.642086303
MAGEA1CST10.64176606
MAGEA1SRP540.640508303
MAGEA1MAGEA110.6383381007
MAGEA1MAGEA100.6356791109
MAGEA1MRPL210.635438504
MAGEA1ZIC50.627033303
MAGEA1CAGE10.621462403
MAGEA1C12orf490.620696303
MAGEA1CCND10.617402403
MAGEA1CST20.615988403
MAGEA1SNCAIP0.614593504
MAGEA1HTR2C0.614562807
MAGEA1OGFOD20.602754403

For details and further investigation, click here