| Full name: chromosome 12 open reading frame 49 | Alias Symbol: FLJ21415 | ||
| Type: protein-coding gene | Cytoband: 12q24.22 | ||
| Entrez ID: 79794 | HGNC ID: HGNC:26128 | Ensembl Gene: ENSG00000111412 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of C12orf49:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf49 | 79794 | 234983_at | 1.6418 | 0.0523 | |
| GSE20347 | C12orf49 | 79794 | 218867_s_at | -0.0253 | 0.8080 | |
| GSE23400 | C12orf49 | 79794 | 218867_s_at | -0.0032 | 0.9407 | |
| GSE26886 | C12orf49 | 79794 | 234983_at | 0.3031 | 0.1729 | |
| GSE29001 | C12orf49 | 79794 | 218867_s_at | -0.0416 | 0.8386 | |
| GSE38129 | C12orf49 | 79794 | 218867_s_at | 0.0895 | 0.4583 | |
| GSE45670 | C12orf49 | 79794 | 234983_at | 0.7671 | 0.0000 | |
| GSE53622 | C12orf49 | 79794 | 150228 | 0.2186 | 0.0222 | |
| GSE53624 | C12orf49 | 79794 | 150228 | 0.0258 | 0.8539 | |
| GSE63941 | C12orf49 | 79794 | 234983_at | 0.4065 | 0.1425 | |
| GSE77861 | C12orf49 | 79794 | 234983_at | 0.3043 | 0.1451 | |
| GSE97050 | C12orf49 | 79794 | A_23_P13797 | 0.2670 | 0.3194 | |
| SRP007169 | C12orf49 | 79794 | RNAseq | -0.5228 | 0.1152 | |
| SRP008496 | C12orf49 | 79794 | RNAseq | -0.3522 | 0.0255 | |
| SRP064894 | C12orf49 | 79794 | RNAseq | 0.1220 | 0.2201 | |
| SRP133303 | C12orf49 | 79794 | RNAseq | 0.2837 | 0.0145 | |
| SRP159526 | C12orf49 | 79794 | RNAseq | 0.5022 | 0.0149 | |
| SRP193095 | C12orf49 | 79794 | RNAseq | -0.0784 | 0.4216 | |
| SRP219564 | C12orf49 | 79794 | RNAseq | -0.2421 | 0.4341 | |
| TCGA | C12orf49 | 79794 | RNAseq | -0.2581 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C12orf49 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf49:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf49 | 79794 | 4 | 3 | 23 | |
| GSE20123 | C12orf49 | 79794 | 4 | 3 | 23 | |
| GSE43470 | C12orf49 | 79794 | 2 | 0 | 41 | |
| GSE46452 | C12orf49 | 79794 | 9 | 1 | 49 | |
| GSE47630 | C12orf49 | 79794 | 9 | 3 | 28 | |
| GSE54993 | C12orf49 | 79794 | 0 | 5 | 65 | |
| GSE54994 | C12orf49 | 79794 | 6 | 5 | 42 | |
| GSE60625 | C12orf49 | 79794 | 0 | 0 | 11 | |
| GSE74703 | C12orf49 | 79794 | 2 | 0 | 34 | |
| GSE74704 | C12orf49 | 79794 | 2 | 2 | 16 | |
| TCGA | C12orf49 | 79794 | 22 | 10 | 64 |
Total number of gains: 60; Total number of losses: 32; Total Number of normals: 396.
Somatic mutations of C12orf49:
Generating mutation plots.
Highly correlated genes for C12orf49:
Showing top 20/952 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf49 | DTX4 | 0.835974 | 3 | 0 | 3 |
| C12orf49 | SMCR8 | 0.816405 | 3 | 0 | 3 |
| C12orf49 | FAM161A | 0.793538 | 3 | 0 | 3 |
| C12orf49 | MTFR2 | 0.77289 | 3 | 0 | 3 |
| C12orf49 | MCM2 | 0.753174 | 3 | 0 | 3 |
| C12orf49 | UBE2T | 0.737923 | 4 | 0 | 4 |
| C12orf49 | KNTC1 | 0.735825 | 4 | 0 | 4 |
| C12orf49 | MAD2L2 | 0.734985 | 3 | 0 | 3 |
| C12orf49 | POLA1 | 0.731504 | 4 | 0 | 4 |
| C12orf49 | DSCC1 | 0.731104 | 4 | 0 | 3 |
| C12orf49 | ZNF273 | 0.729545 | 3 | 0 | 3 |
| C12orf49 | SNRPA | 0.72261 | 3 | 0 | 3 |
| C12orf49 | SMAD1 | 0.720558 | 4 | 0 | 3 |
| C12orf49 | POLR2G | 0.719297 | 4 | 0 | 4 |
| C12orf49 | MCM6 | 0.718793 | 4 | 0 | 3 |
| C12orf49 | AURKA | 0.717287 | 4 | 0 | 4 |
| C12orf49 | PRKDC | 0.716245 | 4 | 0 | 4 |
| C12orf49 | NCAPG2 | 0.715253 | 4 | 0 | 3 |
| C12orf49 | IFI16 | 0.71323 | 5 | 0 | 5 |
| C12orf49 | NAA25 | 0.712565 | 3 | 0 | 3 |
For details and further investigation, click here
