| Full name: cystatin SN | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20p11.21 | ||
| Entrez ID: 1469 | HGNC ID: HGNC:2473 | Ensembl Gene: ENSG00000170373 | OMIM ID: 123855 |
| Drug and gene relationship at DGIdb | |||
Expression of CST1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CST1 | 1469 | 206224_at | 3.8203 | 0.0604 | |
| GSE20347 | CST1 | 1469 | 206224_at | 2.1137 | 0.0000 | |
| GSE23400 | CST1 | 1469 | 206224_at | 1.7562 | 0.0000 | |
| GSE26886 | CST1 | 1469 | 206224_at | 0.7793 | 0.0037 | |
| GSE29001 | CST1 | 1469 | 206224_at | 0.2747 | 0.1000 | |
| GSE38129 | CST1 | 1469 | 206224_at | 3.4070 | 0.0000 | |
| GSE45670 | CST1 | 1469 | 206224_at | 0.3745 | 0.2688 | |
| GSE53622 | CST1 | 1469 | 69686 | 4.8185 | 0.0000 | |
| GSE53624 | CST1 | 1469 | 69686 | 4.0487 | 0.0000 | |
| GSE63941 | CST1 | 1469 | 206224_at | 0.1306 | 0.3464 | |
| GSE77861 | CST1 | 1469 | 206224_at | 0.3071 | 0.4471 | |
| GSE97050 | CST1 | 1469 | A_23_P112859 | 2.8776 | 0.0950 | |
| SRP007169 | CST1 | 1469 | RNAseq | 9.0339 | 0.0000 | |
| SRP008496 | CST1 | 1469 | RNAseq | 7.7481 | 0.0000 | |
| SRP133303 | CST1 | 1469 | RNAseq | 8.7173 | 0.0000 | |
| SRP159526 | CST1 | 1469 | RNAseq | 7.1540 | 0.0000 | |
| SRP219564 | CST1 | 1469 | RNAseq | 10.3021 | 0.0000 | |
| TCGA | CST1 | 1469 | RNAseq | 3.0636 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by CST1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CST1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CST1 | 1469 | 12 | 2 | 16 | |
| GSE20123 | CST1 | 1469 | 12 | 2 | 16 | |
| GSE43470 | CST1 | 1469 | 12 | 1 | 30 | |
| GSE46452 | CST1 | 1469 | 27 | 1 | 31 | |
| GSE47630 | CST1 | 1469 | 17 | 4 | 19 | |
| GSE54993 | CST1 | 1469 | 0 | 17 | 53 | |
| GSE54994 | CST1 | 1469 | 26 | 2 | 25 | |
| GSE60625 | CST1 | 1469 | 0 | 0 | 11 | |
| GSE74703 | CST1 | 1469 | 10 | 1 | 25 | |
| GSE74704 | CST1 | 1469 | 7 | 1 | 12 | |
| TCGA | CST1 | 1469 | 43 | 10 | 43 |
Total number of gains: 166; Total number of losses: 41; Total Number of normals: 281.
Somatic mutations of CST1:
Generating mutation plots.
Highly correlated genes for CST1:
Showing top 20/1115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CST1 | CST4 | 0.823432 | 8 | 0 | 8 |
| CST1 | CST2 | 0.757115 | 11 | 0 | 9 |
| CST1 | SNAP47 | 0.720529 | 3 | 0 | 3 |
| CST1 | MMP11 | 0.716845 | 10 | 0 | 9 |
| CST1 | PYCR2 | 0.710884 | 3 | 0 | 3 |
| CST1 | HAPLN3 | 0.707352 | 3 | 0 | 3 |
| CST1 | COL10A1 | 0.698255 | 11 | 0 | 9 |
| CST1 | HOXD8 | 0.6977 | 5 | 0 | 5 |
| CST1 | MTHFSD | 0.68481 | 3 | 0 | 3 |
| CST1 | NOX4 | 0.682602 | 8 | 0 | 7 |
| CST1 | MTHFD1L | 0.676324 | 3 | 0 | 3 |
| CST1 | GORAB | 0.672316 | 5 | 0 | 4 |
| CST1 | ADAMTS12 | 0.669317 | 7 | 0 | 6 |
| CST1 | BRAT1 | 0.66423 | 4 | 0 | 4 |
| CST1 | HOXA7 | 0.662738 | 4 | 0 | 4 |
| CST1 | DSG2 | 0.658102 | 8 | 0 | 8 |
| CST1 | AGRN | 0.653562 | 9 | 0 | 9 |
| CST1 | MATN3 | 0.653174 | 7 | 0 | 7 |
| CST1 | FLVCR1 | 0.651745 | 5 | 0 | 5 |
| CST1 | PLA2G7 | 0.649517 | 9 | 0 | 7 |
For details and further investigation, click here
