| Full name: synuclein alpha interacting protein | Alias Symbol: SYPH1 | ||
| Type: protein-coding gene | Cytoband: 5q23.2 | ||
| Entrez ID: 9627 | HGNC ID: HGNC:11139 | Ensembl Gene: ENSG00000064692 | OMIM ID: 603779 |
| Drug and gene relationship at DGIdb | |||
Expression of SNCAIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNCAIP | 9627 | 219511_s_at | 1.0372 | 0.1425 | |
| GSE20347 | SNCAIP | 9627 | 219511_s_at | 0.5537 | 0.0003 | |
| GSE23400 | SNCAIP | 9627 | 219511_s_at | 0.3993 | 0.0000 | |
| GSE26886 | SNCAIP | 9627 | 219511_s_at | 1.9636 | 0.0002 | |
| GSE29001 | SNCAIP | 9627 | 219511_s_at | 0.9171 | 0.0583 | |
| GSE38129 | SNCAIP | 9627 | 219511_s_at | 0.6404 | 0.0058 | |
| GSE45670 | SNCAIP | 9627 | 219511_s_at | 0.5516 | 0.1045 | |
| GSE53622 | SNCAIP | 9627 | 119617 | 0.5929 | 0.0000 | |
| GSE53624 | SNCAIP | 9627 | 119617 | 0.5616 | 0.0000 | |
| GSE63941 | SNCAIP | 9627 | 219511_s_at | -0.3414 | 0.7792 | |
| GSE77861 | SNCAIP | 9627 | 219511_s_at | 0.3278 | 0.1055 | |
| GSE97050 | SNCAIP | 9627 | A_23_P19020 | 0.2866 | 0.4389 | |
| SRP007169 | SNCAIP | 9627 | RNAseq | 1.2504 | 0.0943 | |
| SRP064894 | SNCAIP | 9627 | RNAseq | 1.1359 | 0.0002 | |
| SRP133303 | SNCAIP | 9627 | RNAseq | 1.0720 | 0.0162 | |
| SRP159526 | SNCAIP | 9627 | RNAseq | 1.3152 | 0.0067 | |
| SRP193095 | SNCAIP | 9627 | RNAseq | 1.0614 | 0.0000 | |
| SRP219564 | SNCAIP | 9627 | RNAseq | 2.2677 | 0.0000 | |
| TCGA | SNCAIP | 9627 | RNAseq | 0.5775 | 0.0004 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SNCAIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNCAIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNCAIP | 9627 | 1 | 13 | 16 | |
| GSE20123 | SNCAIP | 9627 | 1 | 13 | 16 | |
| GSE43470 | SNCAIP | 9627 | 3 | 8 | 32 | |
| GSE46452 | SNCAIP | 9627 | 0 | 27 | 32 | |
| GSE47630 | SNCAIP | 9627 | 0 | 21 | 19 | |
| GSE54993 | SNCAIP | 9627 | 9 | 1 | 60 | |
| GSE54994 | SNCAIP | 9627 | 2 | 14 | 37 | |
| GSE60625 | SNCAIP | 9627 | 0 | 0 | 11 | |
| GSE74703 | SNCAIP | 9627 | 2 | 6 | 28 | |
| GSE74704 | SNCAIP | 9627 | 1 | 7 | 12 | |
| TCGA | SNCAIP | 9627 | 3 | 40 | 53 |
Total number of gains: 22; Total number of losses: 150; Total Number of normals: 316.
Somatic mutations of SNCAIP:
Generating mutation plots.
Highly correlated genes for SNCAIP:
Showing top 20/229 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNCAIP | IL13RA2 | 0.699252 | 4 | 0 | 4 |
| SNCAIP | ZC3H12C | 0.680244 | 3 | 0 | 3 |
| SNCAIP | GLIS2 | 0.679842 | 3 | 0 | 3 |
| SNCAIP | HMGA2 | 0.679788 | 3 | 0 | 3 |
| SNCAIP | SP4 | 0.673343 | 4 | 0 | 3 |
| SNCAIP | CEACAM19 | 0.673153 | 3 | 0 | 3 |
| SNCAIP | SLC52A1 | 0.666043 | 3 | 0 | 3 |
| SNCAIP | PITX2 | 0.665831 | 4 | 0 | 3 |
| SNCAIP | SLC12A9 | 0.665671 | 5 | 0 | 4 |
| SNCAIP | ATP6V1E2 | 0.663962 | 4 | 0 | 3 |
| SNCAIP | PCSK1 | 0.660489 | 3 | 0 | 3 |
| SNCAIP | UBR5 | 0.651389 | 3 | 0 | 3 |
| SNCAIP | CABYR | 0.646776 | 4 | 0 | 3 |
| SNCAIP | CABLES2 | 0.645181 | 3 | 0 | 3 |
| SNCAIP | ING1 | 0.643842 | 4 | 0 | 3 |
| SNCAIP | ABCA13 | 0.642479 | 5 | 0 | 4 |
| SNCAIP | ZCCHC3 | 0.641969 | 3 | 0 | 3 |
| SNCAIP | ASXL2 | 0.641757 | 3 | 0 | 3 |
| SNCAIP | SEMA3C | 0.637983 | 3 | 0 | 3 |
| SNCAIP | SULT1A1 | 0.635849 | 4 | 0 | 4 |
For details and further investigation, click here
