| Full name: microtubule associated protein 1B | Alias Symbol: MAP5|PPP1R102 | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 4131 | HGNC ID: HGNC:6836 | Ensembl Gene: ENSG00000131711 | OMIM ID: 157129 |
| Drug and gene relationship at DGIdb | |||
Expression of MAP1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAP1B | 4131 | 226084_at | -0.9182 | 0.3832 | |
| GSE20347 | MAP1B | 4131 | 212233_at | 0.7144 | 0.0896 | |
| GSE23400 | MAP1B | 4131 | 212233_at | -0.2523 | 0.2233 | |
| GSE26886 | MAP1B | 4131 | 212233_at | 3.8413 | 0.0000 | |
| GSE29001 | MAP1B | 4131 | 212233_at | 0.7774 | 0.1177 | |
| GSE38129 | MAP1B | 4131 | 212233_at | 0.0325 | 0.9487 | |
| GSE45670 | MAP1B | 4131 | 212233_at | -1.4460 | 0.0178 | |
| GSE53622 | MAP1B | 4131 | 151040 | -0.3457 | 0.0454 | |
| GSE53624 | MAP1B | 4131 | 151040 | 0.0838 | 0.5685 | |
| GSE63941 | MAP1B | 4131 | 226084_at | -1.2062 | 0.6223 | |
| GSE77861 | MAP1B | 4131 | 212233_at | 1.9875 | 0.0021 | |
| GSE97050 | MAP1B | 4131 | A_33_P3343145 | -1.0926 | 0.1363 | |
| SRP007169 | MAP1B | 4131 | RNAseq | 5.3119 | 0.0000 | |
| SRP008496 | MAP1B | 4131 | RNAseq | 5.8700 | 0.0000 | |
| SRP064894 | MAP1B | 4131 | RNAseq | 0.8372 | 0.0485 | |
| SRP133303 | MAP1B | 4131 | RNAseq | -0.2772 | 0.5399 | |
| SRP159526 | MAP1B | 4131 | RNAseq | 1.0253 | 0.0111 | |
| SRP193095 | MAP1B | 4131 | RNAseq | 2.2714 | 0.0000 | |
| SRP219564 | MAP1B | 4131 | RNAseq | -0.2797 | 0.7531 | |
| TCGA | MAP1B | 4131 | RNAseq | -0.2413 | 0.0683 |
Upregulated datasets: 6; Downregulated datasets: 1.
Survival by MAP1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAP1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAP1B | 4131 | 1 | 13 | 16 | |
| GSE20123 | MAP1B | 4131 | 1 | 13 | 16 | |
| GSE43470 | MAP1B | 4131 | 1 | 13 | 29 | |
| GSE46452 | MAP1B | 4131 | 0 | 28 | 31 | |
| GSE47630 | MAP1B | 4131 | 1 | 19 | 20 | |
| GSE54993 | MAP1B | 4131 | 8 | 1 | 61 | |
| GSE54994 | MAP1B | 4131 | 1 | 19 | 33 | |
| GSE60625 | MAP1B | 4131 | 0 | 0 | 11 | |
| GSE74703 | MAP1B | 4131 | 1 | 9 | 26 | |
| GSE74704 | MAP1B | 4131 | 1 | 6 | 13 | |
| TCGA | MAP1B | 4131 | 4 | 51 | 41 |
Total number of gains: 19; Total number of losses: 172; Total Number of normals: 297.
Somatic mutations of MAP1B:
Generating mutation plots.
Highly correlated genes for MAP1B:
Showing top 20/1207 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAP1B | RAD23A | 0.820778 | 3 | 0 | 3 |
| MAP1B | AP1S2 | 0.792018 | 6 | 0 | 6 |
| MAP1B | AKT3 | 0.759577 | 10 | 0 | 10 |
| MAP1B | DOCK11 | 0.759473 | 5 | 0 | 5 |
| MAP1B | FERMT2 | 0.756695 | 12 | 0 | 11 |
| MAP1B | CALD1 | 0.755718 | 11 | 0 | 10 |
| MAP1B | SLC2A12 | 0.754957 | 3 | 0 | 3 |
| MAP1B | MXRA7 | 0.754551 | 10 | 0 | 9 |
| MAP1B | TGFB1I1 | 0.750606 | 11 | 0 | 10 |
| MAP1B | SLC41A1 | 0.748943 | 3 | 0 | 3 |
| MAP1B | MCAM | 0.746892 | 9 | 0 | 8 |
| MAP1B | KLHL13 | 0.745819 | 4 | 0 | 4 |
| MAP1B | C11orf96 | 0.744192 | 4 | 0 | 4 |
| MAP1B | MYADM | 0.738833 | 5 | 0 | 5 |
| MAP1B | SH3RF3 | 0.737591 | 3 | 0 | 3 |
| MAP1B | RHOQ | 0.735116 | 11 | 0 | 9 |
| MAP1B | ZC3H12C | 0.734674 | 3 | 0 | 3 |
| MAP1B | FKBP7 | 0.730471 | 4 | 0 | 4 |
| MAP1B | PKIG | 0.729012 | 11 | 0 | 10 |
| MAP1B | FBN1 | 0.728136 | 9 | 0 | 9 |
For details and further investigation, click here
