| Full name: fermitin family member 2 | Alias Symbol: mig-2|KIND2|UNC112B | ||
| Type: protein-coding gene | Cytoband: 14q22.1 | ||
| Entrez ID: 10979 | HGNC ID: HGNC:15767 | Ensembl Gene: ENSG00000073712 | OMIM ID: 607746 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FERMT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FERMT2 | 10979 | 209210_s_at | -1.2699 | 0.2074 | |
| GSE20347 | FERMT2 | 10979 | 209210_s_at | 0.3973 | 0.4834 | |
| GSE23400 | FERMT2 | 10979 | 209210_s_at | -0.2034 | 0.4540 | |
| GSE26886 | FERMT2 | 10979 | 209210_s_at | 3.0265 | 0.0000 | |
| GSE29001 | FERMT2 | 10979 | 209210_s_at | 0.3899 | 0.6282 | |
| GSE38129 | FERMT2 | 10979 | 209210_s_at | -0.2820 | 0.6424 | |
| GSE45670 | FERMT2 | 10979 | 209210_s_at | -2.7607 | 0.0001 | |
| GSE53622 | FERMT2 | 10979 | 116816 | -0.3910 | 0.0198 | |
| GSE53624 | FERMT2 | 10979 | 53810 | -0.4284 | 0.0005 | |
| GSE63941 | FERMT2 | 10979 | 209210_s_at | -2.6978 | 0.0060 | |
| GSE77861 | FERMT2 | 10979 | 209210_s_at | 1.5176 | 0.0265 | |
| GSE97050 | FERMT2 | 10979 | A_33_P3344482 | -0.7507 | 0.1834 | |
| SRP007169 | FERMT2 | 10979 | RNAseq | 2.9894 | 0.0000 | |
| SRP008496 | FERMT2 | 10979 | RNAseq | 3.2674 | 0.0000 | |
| SRP064894 | FERMT2 | 10979 | RNAseq | -0.0327 | 0.9235 | |
| SRP133303 | FERMT2 | 10979 | RNAseq | 0.1577 | 0.7061 | |
| SRP159526 | FERMT2 | 10979 | RNAseq | -0.3886 | 0.3362 | |
| SRP193095 | FERMT2 | 10979 | RNAseq | 1.3853 | 0.0001 | |
| SRP219564 | FERMT2 | 10979 | RNAseq | -0.3282 | 0.6829 | |
| TCGA | FERMT2 | 10979 | RNAseq | -0.4420 | 0.0002 |
Upregulated datasets: 5; Downregulated datasets: 2.
Survival by FERMT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FERMT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FERMT2 | 10979 | 8 | 3 | 19 | |
| GSE20123 | FERMT2 | 10979 | 8 | 3 | 19 | |
| GSE43470 | FERMT2 | 10979 | 9 | 1 | 33 | |
| GSE46452 | FERMT2 | 10979 | 16 | 3 | 40 | |
| GSE47630 | FERMT2 | 10979 | 11 | 10 | 19 | |
| GSE54993 | FERMT2 | 10979 | 3 | 8 | 59 | |
| GSE54994 | FERMT2 | 10979 | 19 | 4 | 30 | |
| GSE60625 | FERMT2 | 10979 | 0 | 2 | 9 | |
| GSE74703 | FERMT2 | 10979 | 8 | 1 | 27 | |
| GSE74704 | FERMT2 | 10979 | 3 | 2 | 15 | |
| TCGA | FERMT2 | 10979 | 34 | 12 | 50 |
Total number of gains: 119; Total number of losses: 49; Total Number of normals: 320.
Somatic mutations of FERMT2:
Generating mutation plots.
Highly correlated genes for FERMT2:
Showing top 20/1194 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FERMT2 | TGFB1I1 | 0.84087 | 12 | 0 | 12 |
| FERMT2 | ZEB1 | 0.838034 | 3 | 0 | 3 |
| FERMT2 | PDLIM3 | 0.827827 | 13 | 0 | 13 |
| FERMT2 | LAMA4 | 0.826579 | 12 | 0 | 12 |
| FERMT2 | CALD1 | 0.826364 | 13 | 0 | 13 |
| FERMT2 | PMP22 | 0.825213 | 12 | 0 | 12 |
| FERMT2 | TMEM47 | 0.817191 | 13 | 0 | 13 |
| FERMT2 | ATP2B4 | 0.817012 | 5 | 0 | 5 |
| FERMT2 | TPM1 | 0.814483 | 13 | 0 | 13 |
| FERMT2 | FILIP1L | 0.804429 | 13 | 0 | 13 |
| FERMT2 | JAM3 | 0.804294 | 13 | 0 | 13 |
| FERMT2 | ACTA2 | 0.800305 | 13 | 0 | 13 |
| FERMT2 | C11orf96 | 0.797672 | 5 | 0 | 5 |
| FERMT2 | TPM2 | 0.797548 | 13 | 0 | 13 |
| FERMT2 | FBN1 | 0.784632 | 11 | 0 | 11 |
| FERMT2 | MRGPRF | 0.780742 | 8 | 0 | 8 |
| FERMT2 | MYLK | 0.779156 | 13 | 0 | 13 |
| FERMT2 | PKIG | 0.776213 | 13 | 0 | 12 |
| FERMT2 | HMCN1 | 0.770896 | 9 | 0 | 9 |
| FERMT2 | FN1 | 0.768441 | 9 | 0 | 9 |
For details and further investigation, click here
