| Full name: SH3 domain containing ring finger 3 | Alias Symbol: FLJ00204|POSH2 | ||
| Type: protein-coding gene | Cytoband: 2q13 | ||
| Entrez ID: 344558 | HGNC ID: HGNC:24699 | Ensembl Gene: ENSG00000172985 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SH3RF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SH3RF3 | 344558 | 228461_at | 0.2355 | 0.7114 | |
| GSE26886 | SH3RF3 | 344558 | 228461_at | 1.4305 | 0.0000 | |
| GSE45670 | SH3RF3 | 344558 | 228461_at | -0.4682 | 0.1262 | |
| GSE53622 | SH3RF3 | 344558 | 70065 | -0.0622 | 0.5474 | |
| GSE53624 | SH3RF3 | 344558 | 70065 | -0.0956 | 0.3888 | |
| GSE63941 | SH3RF3 | 344558 | 228461_at | -2.9541 | 0.0000 | |
| GSE77861 | SH3RF3 | 344558 | 228461_at | 0.0665 | 0.7423 | |
| GSE97050 | SH3RF3 | 344558 | A_24_P589266 | 0.1626 | 0.6005 | |
| SRP007169 | SH3RF3 | 344558 | RNAseq | 1.7038 | 0.0221 | |
| SRP064894 | SH3RF3 | 344558 | RNAseq | 0.6161 | 0.0127 | |
| SRP133303 | SH3RF3 | 344558 | RNAseq | 0.4548 | 0.1649 | |
| SRP159526 | SH3RF3 | 344558 | RNAseq | 0.6961 | 0.1778 | |
| SRP193095 | SH3RF3 | 344558 | RNAseq | 1.2247 | 0.0000 | |
| SRP219564 | SH3RF3 | 344558 | RNAseq | 0.6750 | 0.1128 | |
| TCGA | SH3RF3 | 344558 | RNAseq | -0.0520 | 0.6846 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by SH3RF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SH3RF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SH3RF3 | 344558 | 4 | 2 | 24 | |
| GSE20123 | SH3RF3 | 344558 | 4 | 2 | 24 | |
| GSE43470 | SH3RF3 | 344558 | 3 | 1 | 39 | |
| GSE46452 | SH3RF3 | 344558 | 1 | 4 | 54 | |
| GSE47630 | SH3RF3 | 344558 | 7 | 0 | 33 | |
| GSE54993 | SH3RF3 | 344558 | 0 | 6 | 64 | |
| GSE54994 | SH3RF3 | 344558 | 10 | 0 | 43 | |
| GSE60625 | SH3RF3 | 344558 | 0 | 3 | 8 | |
| GSE74703 | SH3RF3 | 344558 | 3 | 1 | 32 | |
| GSE74704 | SH3RF3 | 344558 | 2 | 2 | 16 | |
| TCGA | SH3RF3 | 344558 | 31 | 6 | 59 |
Total number of gains: 65; Total number of losses: 27; Total Number of normals: 396.
Somatic mutations of SH3RF3:
Generating mutation plots.
Highly correlated genes for SH3RF3:
Showing top 20/559 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SH3RF3 | MUC6 | 0.861404 | 3 | 0 | 3 |
| SH3RF3 | C12orf65 | 0.848656 | 3 | 0 | 3 |
| SH3RF3 | MLEC | 0.848486 | 3 | 0 | 3 |
| SH3RF3 | ZEB2 | 0.806784 | 3 | 0 | 3 |
| SH3RF3 | DZIP1L | 0.801026 | 3 | 0 | 3 |
| SH3RF3 | MAP4 | 0.799716 | 3 | 0 | 3 |
| SH3RF3 | C11orf96 | 0.793102 | 4 | 0 | 4 |
| SH3RF3 | CCDC102B | 0.790605 | 3 | 0 | 3 |
| SH3RF3 | TCP11L1 | 0.788122 | 3 | 0 | 3 |
| SH3RF3 | LRP4 | 0.78809 | 3 | 0 | 3 |
| SH3RF3 | SLFN12 | 0.767372 | 3 | 0 | 3 |
| SH3RF3 | MYO5A | 0.766795 | 4 | 0 | 4 |
| SH3RF3 | SLC7A6 | 0.766774 | 3 | 0 | 3 |
| SH3RF3 | C20orf194 | 0.765666 | 3 | 0 | 3 |
| SH3RF3 | GMPR | 0.758951 | 3 | 0 | 3 |
| SH3RF3 | HERC2 | 0.757094 | 3 | 0 | 3 |
| SH3RF3 | KIF3B | 0.753345 | 3 | 0 | 3 |
| SH3RF3 | S1PR3 | 0.749567 | 4 | 0 | 4 |
| SH3RF3 | SCRN1 | 0.749005 | 3 | 0 | 3 |
| SH3RF3 | AEBP1 | 0.7464 | 5 | 0 | 5 |
For details and further investigation, click here
