MBD3L2

 

Full name: methyl-CpG binding domain protein 3 like 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 19p13.2
Entrez ID: 125997 HGNC ID: HGNC:18532 Ensembl Gene: ENSG00000230522 OMIM ID: 607964
Drug and gene relationship at DGIdb

 

Expression of MBD3L2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MBD3L2 125997 1552456_a_at 0.3115 0.2321
GSE26886 MBD3L2 125997 1552456_a_at -0.0879 0.6251
GSE45670 MBD3L2 125997 1552456_a_at 0.1228 0.2666
GSE63941 MBD3L2 125997 1552456_a_at 0.0620 0.6862
GSE77861 MBD3L2 125997 1552456_a_at -0.0585 0.7282

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by MBD3L2 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of MBD3L2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MBD3L2 125997 5 3 22
GSE20123 MBD3L2 125997 4 2 24
GSE43470 MBD3L2 125997 2 6 35
GSE46452 MBD3L2 125997 47 1 11
GSE47630 MBD3L2 125997 5 7 28
GSE54993 MBD3L2 125997 16 3 51
GSE54994 MBD3L2 125997 6 14 33
GSE60625 MBD3L2 125997 9 0 2
GSE74703 MBD3L2 125997 2 4 30
GSE74704 MBD3L2 125997 1 2 17
TCGA MBD3L2 125997 8 21 67

Total number of gains: 105; Total number of losses: 63; Total Number of normals: 320.  

 

Somatic mutations of MBD3L2:

 

Generating mutation plots.

 

Highly correlated genes for MBD3L2:

 

Showing all 13 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MBD3L2CPB10.672583303
MBD3L2KCNQ1DN0.634115303
MBD3L2NUDT40.613764303
MBD3L2BCDIN3D-AS10.61343303
MBD3L2P2RX30.610442403
MBD3L2CASC20.58717303
MBD3L2XKR70.585923303
MBD3L2KCNC40.571216303
MBD3L2PPP5C0.56747303
MBD3L2IL270.537499403
MBD3L2MEGF100.535025503
MBD3L2CHRNE0.522328403
MBD3L2NEUROG30.505991503

For details and further investigation, click here