| Full name: carboxypeptidase B1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q24 | ||
| Entrez ID: 1360 | HGNC ID: HGNC:2299 | Ensembl Gene: ENSG00000153002 | OMIM ID: 114852 |
| Drug and gene relationship at DGIdb | |||
Expression of CPB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPB1 | 1360 | 205509_at | 0.1274 | 0.5791 | |
| GSE20347 | CPB1 | 1360 | 205509_at | 0.0520 | 0.6007 | |
| GSE23400 | CPB1 | 1360 | 205509_at | -0.1398 | 0.0553 | |
| GSE26886 | CPB1 | 1360 | 205509_at | 0.2067 | 0.0926 | |
| GSE29001 | CPB1 | 1360 | 205509_at | 0.0752 | 0.7809 | |
| GSE38129 | CPB1 | 1360 | 205509_at | -0.1601 | 0.1210 | |
| GSE45670 | CPB1 | 1360 | 205509_at | 0.2031 | 0.3461 | |
| GSE53622 | CPB1 | 1360 | 10148 | 0.0449 | 0.8296 | |
| GSE53624 | CPB1 | 1360 | 10148 | -0.0258 | 0.9333 | |
| GSE63941 | CPB1 | 1360 | 205509_at | 0.0338 | 0.8585 | |
| GSE77861 | CPB1 | 1360 | 205509_at | -0.0980 | 0.4453 | |
| TCGA | CPB1 | 1360 | RNAseq | -3.8040 | 0.0569 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CPB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPB1 | 1360 | 22 | 0 | 8 | |
| GSE20123 | CPB1 | 1360 | 22 | 0 | 8 | |
| GSE43470 | CPB1 | 1360 | 23 | 0 | 20 | |
| GSE46452 | CPB1 | 1360 | 18 | 2 | 39 | |
| GSE47630 | CPB1 | 1360 | 19 | 3 | 18 | |
| GSE54993 | CPB1 | 1360 | 1 | 10 | 59 | |
| GSE54994 | CPB1 | 1360 | 35 | 1 | 17 | |
| GSE60625 | CPB1 | 1360 | 0 | 6 | 5 | |
| GSE74703 | CPB1 | 1360 | 20 | 0 | 16 | |
| GSE74704 | CPB1 | 1360 | 15 | 0 | 5 | |
| TCGA | CPB1 | 1360 | 71 | 1 | 24 |
Total number of gains: 246; Total number of losses: 23; Total Number of normals: 219.
Somatic mutations of CPB1:
Generating mutation plots.
Highly correlated genes for CPB1:
Showing top 20/150 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPB1 | OLIG3 | 0.734299 | 3 | 0 | 3 |
| CPB1 | MBD3L2 | 0.672583 | 3 | 0 | 3 |
| CPB1 | OR1F1 | 0.633934 | 5 | 0 | 5 |
| CPB1 | ADM2 | 0.633268 | 4 | 0 | 3 |
| CPB1 | GPBAR1 | 0.630751 | 3 | 0 | 3 |
| CPB1 | DAPK2 | 0.621649 | 4 | 0 | 3 |
| CPB1 | CCDC116 | 0.618749 | 3 | 0 | 3 |
| CPB1 | RPGRIP1 | 0.614018 | 5 | 0 | 5 |
| CPB1 | ST7L | 0.611948 | 3 | 0 | 3 |
| CPB1 | TMPRSS5 | 0.611381 | 5 | 0 | 4 |
| CPB1 | PHOX2B | 0.607931 | 6 | 0 | 4 |
| CPB1 | PDE6H | 0.607886 | 4 | 0 | 3 |
| CPB1 | PHOSPHO1 | 0.605859 | 3 | 0 | 3 |
| CPB1 | P2RY4 | 0.603379 | 6 | 0 | 5 |
| CPB1 | SEZ6 | 0.603052 | 3 | 0 | 3 |
| CPB1 | ST8SIA6-AS1 | 0.601878 | 3 | 0 | 3 |
| CPB1 | EPHA6 | 0.60174 | 3 | 0 | 3 |
| CPB1 | KHDRBS2 | 0.590943 | 4 | 0 | 4 |
| CPB1 | HRG | 0.590416 | 5 | 0 | 4 |
| CPB1 | DAND5 | 0.585559 | 3 | 0 | 3 |
For details and further investigation, click here
