| Full name: potassium voltage-gated channel subfamily C member 4 | Alias Symbol: Kv3.4|HKSHIIIC | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 3749 | HGNC ID: HGNC:6236 | Ensembl Gene: ENSG00000116396 | OMIM ID: 176265 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNC4 | 3749 | 228436_at | 0.0209 | 0.9569 | |
| GSE20347 | KCNC4 | 3749 | 208251_at | 0.0137 | 0.8757 | |
| GSE23400 | KCNC4 | 3749 | 208251_at | -0.1186 | 0.0011 | |
| GSE26886 | KCNC4 | 3749 | 208251_at | 0.2786 | 0.0181 | |
| GSE29001 | KCNC4 | 3749 | 208251_at | -0.0826 | 0.6416 | |
| GSE38129 | KCNC4 | 3749 | 208251_at | -0.0453 | 0.5321 | |
| GSE45670 | KCNC4 | 3749 | 235467_s_at | 0.4788 | 0.1399 | |
| GSE53622 | KCNC4 | 3749 | 40985 | 0.6394 | 0.0000 | |
| GSE53624 | KCNC4 | 3749 | 40985 | 0.7286 | 0.0000 | |
| GSE63941 | KCNC4 | 3749 | 228436_at | -0.1860 | 0.4125 | |
| GSE77861 | KCNC4 | 3749 | 228436_at | -0.0052 | 0.9812 | |
| GSE97050 | KCNC4 | 3749 | A_23_P12079 | 0.3969 | 0.1853 | |
| SRP007169 | KCNC4 | 3749 | RNAseq | 0.8492 | 0.2804 | |
| SRP008496 | KCNC4 | 3749 | RNAseq | 1.6614 | 0.0030 | |
| SRP064894 | KCNC4 | 3749 | RNAseq | 0.6223 | 0.0108 | |
| SRP133303 | KCNC4 | 3749 | RNAseq | -0.1528 | 0.3346 | |
| SRP159526 | KCNC4 | 3749 | RNAseq | -0.2625 | 0.3481 | |
| SRP193095 | KCNC4 | 3749 | RNAseq | 0.6613 | 0.0002 | |
| SRP219564 | KCNC4 | 3749 | RNAseq | 0.3478 | 0.1478 | |
| TCGA | KCNC4 | 3749 | RNAseq | -0.3096 | 0.0016 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KCNC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNC4 | 3749 | 0 | 11 | 19 | |
| GSE20123 | KCNC4 | 3749 | 0 | 11 | 19 | |
| GSE43470 | KCNC4 | 3749 | 0 | 9 | 34 | |
| GSE46452 | KCNC4 | 3749 | 2 | 1 | 56 | |
| GSE47630 | KCNC4 | 3749 | 9 | 5 | 26 | |
| GSE54993 | KCNC4 | 3749 | 0 | 1 | 69 | |
| GSE54994 | KCNC4 | 3749 | 7 | 4 | 42 | |
| GSE60625 | KCNC4 | 3749 | 0 | 0 | 11 | |
| GSE74703 | KCNC4 | 3749 | 0 | 7 | 29 | |
| GSE74704 | KCNC4 | 3749 | 0 | 7 | 13 | |
| TCGA | KCNC4 | 3749 | 9 | 26 | 61 |
Total number of gains: 27; Total number of losses: 82; Total Number of normals: 379.
Somatic mutations of KCNC4:
Generating mutation plots.
Highly correlated genes for KCNC4:
Showing top 20/798 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNC4 | TP53I11 | 0.786352 | 4 | 0 | 4 |
| KCNC4 | ITIH6 | 0.766023 | 3 | 0 | 3 |
| KCNC4 | RAB4B | 0.759456 | 3 | 0 | 3 |
| KCNC4 | GGN | 0.757825 | 4 | 0 | 4 |
| KCNC4 | CRTC2 | 0.749783 | 3 | 0 | 3 |
| KCNC4 | MIER2 | 0.743528 | 4 | 0 | 4 |
| KCNC4 | NFAM1 | 0.739792 | 3 | 0 | 3 |
| KCNC4 | CNTD1 | 0.736682 | 3 | 0 | 3 |
| KCNC4 | GRIN3A | 0.732206 | 3 | 0 | 3 |
| KCNC4 | TTC9B | 0.7317 | 3 | 0 | 3 |
| KCNC4 | LINC00598 | 0.731393 | 3 | 0 | 3 |
| KCNC4 | INO80E | 0.723887 | 3 | 0 | 3 |
| KCNC4 | IL17F | 0.723634 | 3 | 0 | 3 |
| KCNC4 | ZNF213 | 0.72273 | 3 | 0 | 3 |
| KCNC4 | ZNF683 | 0.721971 | 3 | 0 | 3 |
| KCNC4 | MZF1 | 0.720421 | 3 | 0 | 3 |
| KCNC4 | CISH | 0.718406 | 5 | 0 | 4 |
| KCNC4 | RAC3 | 0.713507 | 4 | 0 | 4 |
| KCNC4 | MTMR11 | 0.703609 | 3 | 0 | 3 |
| KCNC4 | AKR1E2 | 0.699222 | 3 | 0 | 3 |
For details and further investigation, click here
