| Full name: nudix hydrolase 4 | Alias Symbol: DIPP2|HDCMB47P|KIAA0487|DIPP2alpha|DIPP2beta | ||
| Type: protein-coding gene | Cytoband: 12q22 | ||
| Entrez ID: 11163 | HGNC ID: HGNC:8051 | Ensembl Gene: ENSG00000173598 | OMIM ID: 609229 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUDT4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUDT4 | 11163 | 229836_s_at | 0.2160 | 0.4278 | |
| GSE20347 | NUDT4 | 11163 | 212182_at | -0.0893 | 0.2570 | |
| GSE23400 | NUDT4 | 11163 | 212182_at | -0.0236 | 0.5206 | |
| GSE26886 | NUDT4 | 11163 | 227683_x_at | -0.0431 | 0.7622 | |
| GSE29001 | NUDT4 | 11163 | 212182_at | -0.0925 | 0.7279 | |
| GSE38129 | NUDT4 | 11163 | 212182_at | -0.1397 | 0.0996 | |
| GSE45670 | NUDT4 | 11163 | 227683_x_at | 0.0252 | 0.8127 | |
| GSE53622 | NUDT4 | 11163 | 120153 | 0.1843 | 0.0628 | |
| GSE53624 | NUDT4 | 11163 | 62336 | 0.0220 | 0.7044 | |
| GSE63941 | NUDT4 | 11163 | 227683_x_at | 0.4623 | 0.0613 | |
| GSE77861 | NUDT4 | 11163 | 229836_s_at | -0.0475 | 0.7509 | |
| GSE97050 | NUDT4 | 11163 | A_24_P50753 | -0.6157 | 0.1760 | |
| SRP007169 | NUDT4 | 11163 | RNAseq | 0.2245 | 0.6428 | |
| SRP008496 | NUDT4 | 11163 | RNAseq | 0.4103 | 0.2029 | |
| SRP064894 | NUDT4 | 11163 | RNAseq | 0.0947 | 0.7017 | |
| SRP133303 | NUDT4 | 11163 | RNAseq | -0.0452 | 0.8148 | |
| SRP159526 | NUDT4 | 11163 | RNAseq | -0.1004 | 0.6555 | |
| SRP193095 | NUDT4 | 11163 | RNAseq | -0.0096 | 0.9283 | |
| SRP219564 | NUDT4 | 11163 | RNAseq | -0.3222 | 0.7388 | |
| TCGA | NUDT4 | 11163 | RNAseq | -0.2302 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUDT4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUDT4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDT4 | 11163 | 3 | 2 | 25 | |
| GSE20123 | NUDT4 | 11163 | 3 | 2 | 25 | |
| GSE43470 | NUDT4 | 11163 | 3 | 0 | 40 | |
| GSE46452 | NUDT4 | 11163 | 9 | 1 | 49 | |
| GSE47630 | NUDT4 | 11163 | 10 | 1 | 29 | |
| GSE54993 | NUDT4 | 11163 | 0 | 5 | 65 | |
| GSE54994 | NUDT4 | 11163 | 6 | 1 | 46 | |
| GSE60625 | NUDT4 | 11163 | 0 | 0 | 11 | |
| GSE74703 | NUDT4 | 11163 | 3 | 0 | 33 | |
| GSE74704 | NUDT4 | 11163 | 1 | 2 | 17 | |
| TCGA | NUDT4 | 11163 | 17 | 11 | 68 |
Total number of gains: 55; Total number of losses: 25; Total Number of normals: 408.
Somatic mutations of NUDT4:
Generating mutation plots.
Highly correlated genes for NUDT4:
Showing top 20/212 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDT4 | B4GALNT4 | 0.765801 | 3 | 0 | 3 |
| NUDT4 | DDX19A | 0.761489 | 3 | 0 | 3 |
| NUDT4 | DNAJA3 | 0.759885 | 3 | 0 | 3 |
| NUDT4 | GCLC | 0.757645 | 3 | 0 | 3 |
| NUDT4 | MRPL38 | 0.752887 | 3 | 0 | 3 |
| NUDT4 | KCTD2 | 0.751988 | 3 | 0 | 3 |
| NUDT4 | CTDSPL2 | 0.75057 | 3 | 0 | 3 |
| NUDT4 | UBE2D4 | 0.735531 | 3 | 0 | 3 |
| NUDT4 | RFX2 | 0.732623 | 3 | 0 | 3 |
| NUDT4 | EHD1 | 0.730494 | 3 | 0 | 3 |
| NUDT4 | CWF19L1 | 0.727332 | 3 | 0 | 3 |
| NUDT4 | ZACN | 0.725824 | 3 | 0 | 3 |
| NUDT4 | SMARCD1 | 0.722261 | 3 | 0 | 3 |
| NUDT4 | LSM12 | 0.722151 | 3 | 0 | 3 |
| NUDT4 | STRN4 | 0.719826 | 3 | 0 | 3 |
| NUDT4 | SETD5 | 0.717871 | 3 | 0 | 3 |
| NUDT4 | PHF5A | 0.715272 | 3 | 0 | 3 |
| NUDT4 | MRPL47 | 0.713912 | 3 | 0 | 3 |
| NUDT4 | USP34 | 0.702378 | 3 | 0 | 3 |
| NUDT4 | ZFC3H1 | 0.701146 | 3 | 0 | 3 |
For details and further investigation, click here
