| Full name: mediator complex subunit 29 | Alias Symbol: DKFZp434H247|MED2 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 55588 | HGNC ID: HGNC:23074 | Ensembl Gene: ENSG00000063322 | OMIM ID: 612914 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MED29:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED29 | 55588 | 225708_at | 0.0886 | 0.7959 | |
| GSE26886 | MED29 | 55588 | 225708_at | 0.3226 | 0.1958 | |
| GSE45670 | MED29 | 55588 | 225708_at | 0.0789 | 0.5712 | |
| GSE53622 | MED29 | 55588 | 9358 | 0.1061 | 0.1077 | |
| GSE53624 | MED29 | 55588 | 9358 | 0.2582 | 0.0000 | |
| GSE63941 | MED29 | 55588 | 225708_at | -1.0812 | 0.0325 | |
| GSE77861 | MED29 | 55588 | 225708_at | 0.4946 | 0.0703 | |
| GSE97050 | MED29 | 55588 | A_23_P336929 | -0.0951 | 0.6965 | |
| SRP007169 | MED29 | 55588 | RNAseq | 0.2846 | 0.4323 | |
| SRP008496 | MED29 | 55588 | RNAseq | 0.0853 | 0.7149 | |
| SRP064894 | MED29 | 55588 | RNAseq | 0.3805 | 0.0098 | |
| SRP133303 | MED29 | 55588 | RNAseq | 0.3204 | 0.0337 | |
| SRP159526 | MED29 | 55588 | RNAseq | 0.3714 | 0.0276 | |
| SRP193095 | MED29 | 55588 | RNAseq | 0.0157 | 0.8726 | |
| SRP219564 | MED29 | 55588 | RNAseq | 0.0059 | 0.9856 | |
| TCGA | MED29 | 55588 | RNAseq | -0.0576 | 0.2149 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MED29 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MED29:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED29 | 55588 | 7 | 4 | 19 | |
| GSE20123 | MED29 | 55588 | 7 | 3 | 20 | |
| GSE43470 | MED29 | 55588 | 3 | 11 | 29 | |
| GSE46452 | MED29 | 55588 | 48 | 1 | 10 | |
| GSE47630 | MED29 | 55588 | 9 | 5 | 26 | |
| GSE54993 | MED29 | 55588 | 17 | 3 | 50 | |
| GSE54994 | MED29 | 55588 | 7 | 9 | 37 | |
| GSE60625 | MED29 | 55588 | 9 | 0 | 2 | |
| GSE74703 | MED29 | 55588 | 3 | 7 | 26 | |
| GSE74704 | MED29 | 55588 | 7 | 1 | 12 | |
| TCGA | MED29 | 55588 | 14 | 16 | 66 |
Total number of gains: 131; Total number of losses: 60; Total Number of normals: 297.
Somatic mutations of MED29:
Generating mutation plots.
Highly correlated genes for MED29:
Showing top 20/252 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED29 | DGKH | 0.779965 | 3 | 0 | 3 |
| MED29 | RGL1 | 0.779324 | 3 | 0 | 3 |
| MED29 | RBM41 | 0.773113 | 3 | 0 | 3 |
| MED29 | RYBP | 0.772091 | 3 | 0 | 3 |
| MED29 | EEF1D | 0.772033 | 3 | 0 | 3 |
| MED29 | RILPL2 | 0.769924 | 3 | 0 | 3 |
| MED29 | CHD1 | 0.762645 | 3 | 0 | 3 |
| MED29 | HNRNPUL2 | 0.760706 | 3 | 0 | 3 |
| MED29 | AKT2 | 0.753969 | 3 | 0 | 3 |
| MED29 | GDE1 | 0.751801 | 3 | 0 | 3 |
| MED29 | PET117 | 0.750097 | 4 | 0 | 4 |
| MED29 | KLHL20 | 0.748586 | 3 | 0 | 3 |
| MED29 | CCS | 0.748189 | 3 | 0 | 3 |
| MED29 | PLEKHM3 | 0.74779 | 3 | 0 | 3 |
| MED29 | HTATSF1 | 0.738854 | 3 | 0 | 3 |
| MED29 | GPRASP1 | 0.735429 | 3 | 0 | 3 |
| MED29 | WDR81 | 0.734893 | 3 | 0 | 3 |
| MED29 | PTP4A2 | 0.734766 | 3 | 0 | 3 |
| MED29 | MTCP1 | 0.730165 | 3 | 0 | 3 |
| MED29 | BTG3 | 0.728079 | 3 | 0 | 3 |
For details and further investigation, click here
