| Full name: diacylglycerol kinase eta | Alias Symbol: DGKeta | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 160851 | HGNC ID: HGNC:2854 | Ensembl Gene: ENSG00000102780 | OMIM ID: 604071 |
| Drug and gene relationship at DGIdb | |||
Expression of DGKH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DGKH | 160851 | 227415_at | 0.4942 | 0.2830 | |
| GSE20347 | DGKH | 160851 | 216349_at | -0.1229 | 0.0576 | |
| GSE23400 | DGKH | 160851 | 216349_at | -0.1210 | 0.0000 | |
| GSE26886 | DGKH | 160851 | 227415_at | 1.0312 | 0.0001 | |
| GSE29001 | DGKH | 160851 | 216349_at | 0.0350 | 0.8276 | |
| GSE38129 | DGKH | 160851 | 216349_at | -0.0781 | 0.1671 | |
| GSE45670 | DGKH | 160851 | 227415_at | 0.2242 | 0.3999 | |
| GSE53622 | DGKH | 160851 | 52768 | 0.3799 | 0.0041 | |
| GSE53624 | DGKH | 160851 | 34219 | 0.4898 | 0.0000 | |
| GSE63941 | DGKH | 160851 | 227415_at | 0.5564 | 0.4959 | |
| GSE77861 | DGKH | 160851 | 227415_at | 1.0264 | 0.0359 | |
| GSE97050 | DGKH | 160851 | A_23_P502980 | 0.1731 | 0.4831 | |
| SRP007169 | DGKH | 160851 | RNAseq | 1.1676 | 0.0169 | |
| SRP008496 | DGKH | 160851 | RNAseq | 1.1862 | 0.0005 | |
| SRP064894 | DGKH | 160851 | RNAseq | 0.5751 | 0.0470 | |
| SRP133303 | DGKH | 160851 | RNAseq | 0.3587 | 0.0645 | |
| SRP159526 | DGKH | 160851 | RNAseq | 0.2134 | 0.6915 | |
| SRP193095 | DGKH | 160851 | RNAseq | 0.6833 | 0.0001 | |
| SRP219564 | DGKH | 160851 | RNAseq | 0.0328 | 0.9294 | |
| TCGA | DGKH | 160851 | RNAseq | 0.4040 | 0.0060 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by DGKH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DGKH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DGKH | 160851 | 0 | 13 | 17 | |
| GSE20123 | DGKH | 160851 | 0 | 12 | 18 | |
| GSE43470 | DGKH | 160851 | 3 | 13 | 27 | |
| GSE46452 | DGKH | 160851 | 0 | 33 | 26 | |
| GSE47630 | DGKH | 160851 | 2 | 27 | 11 | |
| GSE54993 | DGKH | 160851 | 12 | 2 | 56 | |
| GSE54994 | DGKH | 160851 | 1 | 16 | 36 | |
| GSE60625 | DGKH | 160851 | 0 | 3 | 8 | |
| GSE74703 | DGKH | 160851 | 3 | 10 | 23 | |
| GSE74704 | DGKH | 160851 | 0 | 9 | 11 | |
| TCGA | DGKH | 160851 | 8 | 40 | 48 |
Total number of gains: 29; Total number of losses: 178; Total Number of normals: 281.
Somatic mutations of DGKH:
Generating mutation plots.
Highly correlated genes for DGKH:
Showing top 20/601 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DGKH | SGTB | 0.875148 | 3 | 0 | 3 |
| DGKH | NOL9 | 0.816368 | 3 | 0 | 3 |
| DGKH | UBB | 0.80747 | 3 | 0 | 3 |
| DGKH | DOCK11 | 0.796767 | 3 | 0 | 3 |
| DGKH | RILPL2 | 0.794767 | 3 | 0 | 3 |
| DGKH | SEC22C | 0.790767 | 3 | 0 | 3 |
| DGKH | KBTBD6 | 0.789506 | 4 | 0 | 4 |
| DGKH | CHD8 | 0.783953 | 3 | 0 | 3 |
| DGKH | SOAT1 | 0.782218 | 3 | 0 | 3 |
| DGKH | MED29 | 0.779965 | 3 | 0 | 3 |
| DGKH | CCDC15 | 0.777544 | 3 | 0 | 3 |
| DGKH | NENF | 0.776515 | 4 | 0 | 4 |
| DGKH | TMEM17 | 0.771572 | 3 | 0 | 3 |
| DGKH | ERVW-1 | 0.771391 | 3 | 0 | 3 |
| DGKH | AMMECR1L | 0.771258 | 5 | 0 | 5 |
| DGKH | SNRNP48 | 0.769128 | 3 | 0 | 3 |
| DGKH | SLC30A6 | 0.766533 | 3 | 0 | 3 |
| DGKH | FAM20C | 0.766193 | 3 | 0 | 3 |
| DGKH | DBN1 | 0.765423 | 3 | 0 | 3 |
| DGKH | CDKN1C | 0.76513 | 3 | 0 | 3 |
For details and further investigation, click here
