| Full name: pleckstrin homology domain containing M3 | Alias Symbol: DAPR | ||
| Type: protein-coding gene | Cytoband: 2q33.3 | ||
| Entrez ID: 389072 | HGNC ID: HGNC:34006 | Ensembl Gene: ENSG00000178385 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PLEKHM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLEKHM3 | 389072 | 235360_at | 0.0097 | 0.9894 | |
| GSE26886 | PLEKHM3 | 389072 | 235360_at | 0.2511 | 0.3514 | |
| GSE45670 | PLEKHM3 | 389072 | 235360_at | -0.0186 | 0.9402 | |
| GSE53622 | PLEKHM3 | 389072 | 41448 | 0.2344 | 0.0110 | |
| GSE53624 | PLEKHM3 | 389072 | 41448 | 0.2956 | 0.0000 | |
| GSE63941 | PLEKHM3 | 389072 | 235360_at | -1.3351 | 0.0074 | |
| GSE77861 | PLEKHM3 | 389072 | 235360_at | 0.4299 | 0.0129 | |
| GSE97050 | PLEKHM3 | 389072 | A_33_P3336657 | -0.2096 | 0.3524 | |
| SRP007169 | PLEKHM3 | 389072 | RNAseq | 0.0571 | 0.8905 | |
| SRP008496 | PLEKHM3 | 389072 | RNAseq | 0.6751 | 0.0241 | |
| SRP064894 | PLEKHM3 | 389072 | RNAseq | -0.1946 | 0.4757 | |
| SRP133303 | PLEKHM3 | 389072 | RNAseq | 0.1265 | 0.3595 | |
| SRP159526 | PLEKHM3 | 389072 | RNAseq | -0.0499 | 0.8750 | |
| SRP193095 | PLEKHM3 | 389072 | RNAseq | 0.2889 | 0.0036 | |
| SRP219564 | PLEKHM3 | 389072 | RNAseq | -0.0915 | 0.7882 | |
| TCGA | PLEKHM3 | 389072 | RNAseq | -0.1795 | 0.0055 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PLEKHM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLEKHM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLEKHM3 | 389072 | 3 | 9 | 18 | |
| GSE20123 | PLEKHM3 | 389072 | 3 | 9 | 18 | |
| GSE43470 | PLEKHM3 | 389072 | 2 | 4 | 37 | |
| GSE46452 | PLEKHM3 | 389072 | 1 | 4 | 54 | |
| GSE47630 | PLEKHM3 | 389072 | 4 | 5 | 31 | |
| GSE54993 | PLEKHM3 | 389072 | 0 | 3 | 67 | |
| GSE54994 | PLEKHM3 | 389072 | 9 | 9 | 35 | |
| GSE60625 | PLEKHM3 | 389072 | 0 | 3 | 8 | |
| GSE74703 | PLEKHM3 | 389072 | 2 | 3 | 31 | |
| GSE74704 | PLEKHM3 | 389072 | 2 | 4 | 14 | |
| TCGA | PLEKHM3 | 389072 | 15 | 21 | 60 |
Total number of gains: 41; Total number of losses: 74; Total Number of normals: 373.
Somatic mutations of PLEKHM3:
Generating mutation plots.
Highly correlated genes for PLEKHM3:
Showing top 20/273 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLEKHM3 | C1orf216 | 0.81535 | 3 | 0 | 3 |
| PLEKHM3 | PALB2 | 0.793556 | 3 | 0 | 3 |
| PLEKHM3 | AP4E1 | 0.790222 | 3 | 0 | 3 |
| PLEKHM3 | ZNF319 | 0.789739 | 3 | 0 | 3 |
| PLEKHM3 | ABL2 | 0.78257 | 3 | 0 | 3 |
| PLEKHM3 | RRAS2 | 0.780474 | 3 | 0 | 3 |
| PLEKHM3 | CEBPB | 0.780116 | 3 | 0 | 3 |
| PLEKHM3 | C16orf72 | 0.776044 | 3 | 0 | 3 |
| PLEKHM3 | RRN3 | 0.775078 | 4 | 0 | 4 |
| PLEKHM3 | RCN2 | 0.768665 | 3 | 0 | 3 |
| PLEKHM3 | TERF2IP | 0.767326 | 3 | 0 | 3 |
| PLEKHM3 | UBE2Q2 | 0.767053 | 3 | 0 | 3 |
| PLEKHM3 | RGL1 | 0.766574 | 3 | 0 | 3 |
| PLEKHM3 | BNIP2 | 0.764422 | 3 | 0 | 3 |
| PLEKHM3 | THAP1 | 0.755506 | 3 | 0 | 3 |
| PLEKHM3 | SLC37A3 | 0.753495 | 4 | 0 | 4 |
| PLEKHM3 | PRNP | 0.752716 | 3 | 0 | 3 |
| PLEKHM3 | EVI5 | 0.749896 | 3 | 0 | 3 |
| PLEKHM3 | ZMPSTE24 | 0.748762 | 3 | 0 | 3 |
| PLEKHM3 | MED29 | 0.74779 | 3 | 0 | 3 |
For details and further investigation, click here
