| Full name: BTG anti-proliferation factor 3 | Alias Symbol: ANA|tob55|APRO4|ANA/BTG3 | ||
| Type: protein-coding gene | Cytoband: 21q21.1 | ||
| Entrez ID: 10950 | HGNC ID: HGNC:1132 | Ensembl Gene: ENSG00000154640 | OMIM ID: 605674 |
| Drug and gene relationship at DGIdb | |||
Expression of BTG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BTG3 | 10950 | 213134_x_at | 0.5330 | 0.2189 | |
| GSE20347 | BTG3 | 10950 | 213134_x_at | 0.9310 | 0.0000 | |
| GSE23400 | BTG3 | 10950 | 213134_x_at | 1.0296 | 0.0000 | |
| GSE26886 | BTG3 | 10950 | 213134_x_at | 1.2574 | 0.0003 | |
| GSE29001 | BTG3 | 10950 | 213134_x_at | 1.2651 | 0.0010 | |
| GSE38129 | BTG3 | 10950 | 213134_x_at | 1.0063 | 0.0000 | |
| GSE45670 | BTG3 | 10950 | 213134_x_at | 0.9098 | 0.0001 | |
| GSE53622 | BTG3 | 10950 | 7662 | 0.5179 | 0.0000 | |
| GSE53624 | BTG3 | 10950 | 7662 | 0.8855 | 0.0000 | |
| GSE63941 | BTG3 | 10950 | 213134_x_at | 0.6042 | 0.3275 | |
| GSE77861 | BTG3 | 10950 | 213134_x_at | 0.6372 | 0.0552 | |
| GSE97050 | BTG3 | 10950 | A_23_P80068 | 0.4018 | 0.1512 | |
| SRP007169 | BTG3 | 10950 | RNAseq | 0.3552 | 0.3605 | |
| SRP008496 | BTG3 | 10950 | RNAseq | 0.4967 | 0.0924 | |
| SRP064894 | BTG3 | 10950 | RNAseq | 0.8212 | 0.0011 | |
| SRP133303 | BTG3 | 10950 | RNAseq | 0.7032 | 0.0001 | |
| SRP159526 | BTG3 | 10950 | RNAseq | 0.6850 | 0.0047 | |
| SRP193095 | BTG3 | 10950 | RNAseq | 0.3547 | 0.0180 | |
| SRP219564 | BTG3 | 10950 | RNAseq | 0.0634 | 0.8916 | |
| TCGA | BTG3 | 10950 | RNAseq | 0.2540 | 0.0002 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by BTG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BTG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BTG3 | 10950 | 2 | 9 | 19 | |
| GSE20123 | BTG3 | 10950 | 2 | 9 | 19 | |
| GSE43470 | BTG3 | 10950 | 1 | 11 | 31 | |
| GSE46452 | BTG3 | 10950 | 1 | 22 | 36 | |
| GSE47630 | BTG3 | 10950 | 6 | 17 | 17 | |
| GSE54993 | BTG3 | 10950 | 9 | 2 | 59 | |
| GSE54994 | BTG3 | 10950 | 3 | 10 | 40 | |
| GSE60625 | BTG3 | 10950 | 0 | 0 | 11 | |
| GSE74703 | BTG3 | 10950 | 1 | 8 | 27 | |
| GSE74704 | BTG3 | 10950 | 2 | 6 | 12 | |
| TCGA | BTG3 | 10950 | 10 | 42 | 44 |
Total number of gains: 37; Total number of losses: 136; Total Number of normals: 315.
Somatic mutations of BTG3:
Generating mutation plots.
Highly correlated genes for BTG3:
Showing top 20/1382 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BTG3 | MRPS5 | 0.743577 | 3 | 0 | 3 |
| BTG3 | FHL3 | 0.729651 | 4 | 0 | 3 |
| BTG3 | MED29 | 0.728079 | 3 | 0 | 3 |
| BTG3 | ARL10 | 0.719694 | 3 | 0 | 3 |
| BTG3 | FAM89A | 0.715714 | 3 | 0 | 3 |
| BTG3 | NQO2 | 0.708387 | 3 | 0 | 3 |
| BTG3 | SCYL1 | 0.701915 | 4 | 0 | 4 |
| BTG3 | BORA | 0.700065 | 8 | 0 | 8 |
| BTG3 | RPTOR | 0.684957 | 3 | 0 | 3 |
| BTG3 | C6orf141 | 0.683022 | 4 | 0 | 4 |
| BTG3 | ZFP1 | 0.682633 | 4 | 0 | 4 |
| BTG3 | COL9A3 | 0.681337 | 3 | 0 | 3 |
| BTG3 | DMTF1 | 0.679211 | 3 | 0 | 3 |
| BTG3 | TAOK1 | 0.678173 | 3 | 0 | 3 |
| BTG3 | TMEM173 | 0.676262 | 3 | 0 | 3 |
| BTG3 | HES6 | 0.676011 | 3 | 0 | 3 |
| BTG3 | RNASEH1-AS1 | 0.675868 | 3 | 0 | 3 |
| BTG3 | GLS | 0.674515 | 6 | 0 | 5 |
| BTG3 | PHF5A | 0.672143 | 5 | 0 | 4 |
| BTG3 | PRDM15 | 0.671872 | 3 | 0 | 3 |
For details and further investigation, click here
