| Full name: Meis homeobox 2 | Alias Symbol: MRG1|HsT18361 | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 4212 | HGNC ID: HGNC:7001 | Ensembl Gene: ENSG00000134138 | OMIM ID: 601740 |
| Drug and gene relationship at DGIdb | |||
Expression of MEIS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEIS2 | 4212 | 207480_s_at | -1.4245 | 0.0294 | |
| GSE20347 | MEIS2 | 4212 | 207480_s_at | -0.7386 | 0.0002 | |
| GSE23400 | MEIS2 | 4212 | 207480_s_at | -0.3900 | 0.0188 | |
| GSE26886 | MEIS2 | 4212 | 207480_s_at | 0.7385 | 0.0631 | |
| GSE29001 | MEIS2 | 4212 | 207480_s_at | -0.4190 | 0.1863 | |
| GSE38129 | MEIS2 | 4212 | 207480_s_at | -0.8685 | 0.0000 | |
| GSE45670 | MEIS2 | 4212 | 207480_s_at | -1.2705 | 0.0000 | |
| GSE53622 | MEIS2 | 4212 | 11949 | -0.8628 | 0.0000 | |
| GSE53624 | MEIS2 | 4212 | 11949 | -0.7963 | 0.0000 | |
| GSE63941 | MEIS2 | 4212 | 207480_s_at | -1.4993 | 0.0344 | |
| GSE77861 | MEIS2 | 4212 | 207480_s_at | -0.0186 | 0.9687 | |
| GSE97050 | MEIS2 | 4212 | A_23_P88602 | -1.4704 | 0.0502 | |
| SRP007169 | MEIS2 | 4212 | RNAseq | 0.6493 | 0.1033 | |
| SRP008496 | MEIS2 | 4212 | RNAseq | 0.7237 | 0.0272 | |
| SRP064894 | MEIS2 | 4212 | RNAseq | -0.4887 | 0.0290 | |
| SRP133303 | MEIS2 | 4212 | RNAseq | -0.5160 | 0.0706 | |
| SRP159526 | MEIS2 | 4212 | RNAseq | -0.6350 | 0.2248 | |
| SRP193095 | MEIS2 | 4212 | RNAseq | -0.3740 | 0.1175 | |
| SRP219564 | MEIS2 | 4212 | RNAseq | -0.7296 | 0.3468 | |
| TCGA | MEIS2 | 4212 | RNAseq | -0.3274 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by MEIS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEIS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEIS2 | 4212 | 2 | 7 | 21 | |
| GSE20123 | MEIS2 | 4212 | 2 | 7 | 21 | |
| GSE43470 | MEIS2 | 4212 | 4 | 5 | 34 | |
| GSE46452 | MEIS2 | 4212 | 3 | 7 | 49 | |
| GSE47630 | MEIS2 | 4212 | 8 | 11 | 21 | |
| GSE54993 | MEIS2 | 4212 | 4 | 6 | 60 | |
| GSE54994 | MEIS2 | 4212 | 5 | 7 | 41 | |
| GSE60625 | MEIS2 | 4212 | 4 | 0 | 7 | |
| GSE74703 | MEIS2 | 4212 | 4 | 4 | 28 | |
| GSE74704 | MEIS2 | 4212 | 1 | 6 | 13 | |
| TCGA | MEIS2 | 4212 | 11 | 18 | 67 |
Total number of gains: 48; Total number of losses: 78; Total Number of normals: 362.
Somatic mutations of MEIS2:
Generating mutation plots.
Highly correlated genes for MEIS2:
Showing top 20/1057 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEIS2 | HOXA3 | 0.809383 | 3 | 0 | 3 |
| MEIS2 | DNAJC18 | 0.799658 | 3 | 0 | 3 |
| MEIS2 | KCNB1 | 0.793555 | 4 | 0 | 4 |
| MEIS2 | FAM13C | 0.790036 | 4 | 0 | 4 |
| MEIS2 | UBXN10 | 0.779019 | 3 | 0 | 3 |
| MEIS2 | ADAMTS9-AS2 | 0.776413 | 4 | 0 | 4 |
| MEIS2 | TCEAL6 | 0.76643 | 3 | 0 | 3 |
| MEIS2 | INTS6 | 0.764974 | 3 | 0 | 3 |
| MEIS2 | HPSE2 | 0.763564 | 6 | 0 | 6 |
| MEIS2 | CACNB2 | 0.759313 | 7 | 0 | 7 |
| MEIS2 | RHOJ | 0.752899 | 4 | 0 | 4 |
| MEIS2 | MRVI1 | 0.748049 | 7 | 0 | 7 |
| MEIS2 | SORCS1 | 0.743893 | 4 | 0 | 4 |
| MEIS2 | ZNF570 | 0.736855 | 3 | 0 | 3 |
| MEIS2 | SMTNL2 | 0.736358 | 5 | 0 | 5 |
| MEIS2 | ANKS1B | 0.735782 | 3 | 0 | 3 |
| MEIS2 | NR2F1 | 0.732806 | 3 | 0 | 3 |
| MEIS2 | SMIM10 | 0.73094 | 5 | 0 | 5 |
| MEIS2 | RGN | 0.730299 | 6 | 0 | 5 |
| MEIS2 | RASSF3 | 0.727319 | 6 | 0 | 5 |
For details and further investigation, click here
