| Full name: Ras association domain family member 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q14.2 | ||
| Entrez ID: 283349 | HGNC ID: HGNC:14271 | Ensembl Gene: ENSG00000153179 | OMIM ID: 607019 |
| Drug and gene relationship at DGIdb | |||
Expression of RASSF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RASSF3 | 283349 | 227167_s_at | -0.8091 | 0.2044 | |
| GSE26886 | RASSF3 | 283349 | 230466_s_at | 0.6435 | 0.0903 | |
| GSE45670 | RASSF3 | 283349 | 227167_s_at | -1.0980 | 0.0000 | |
| GSE53622 | RASSF3 | 283349 | 33462 | -1.2530 | 0.0000 | |
| GSE53624 | RASSF3 | 283349 | 33462 | -2.0063 | 0.0000 | |
| GSE63941 | RASSF3 | 283349 | 227167_s_at | -0.2436 | 0.7135 | |
| GSE77861 | RASSF3 | 283349 | 227167_s_at | 0.2528 | 0.5727 | |
| GSE97050 | RASSF3 | 283349 | A_23_P2397 | -0.7441 | 0.1752 | |
| SRP007169 | RASSF3 | 283349 | RNAseq | 0.3005 | 0.3663 | |
| SRP008496 | RASSF3 | 283349 | RNAseq | 0.0768 | 0.7029 | |
| SRP064894 | RASSF3 | 283349 | RNAseq | -0.1648 | 0.4828 | |
| SRP133303 | RASSF3 | 283349 | RNAseq | 0.1204 | 0.7448 | |
| SRP159526 | RASSF3 | 283349 | RNAseq | -0.6994 | 0.0000 | |
| SRP193095 | RASSF3 | 283349 | RNAseq | -0.0100 | 0.9620 | |
| SRP219564 | RASSF3 | 283349 | RNAseq | -0.5675 | 0.4032 | |
| TCGA | RASSF3 | 283349 | RNAseq | -0.6009 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RASSF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RASSF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RASSF3 | 283349 | 5 | 2 | 23 | |
| GSE20123 | RASSF3 | 283349 | 5 | 1 | 24 | |
| GSE43470 | RASSF3 | 283349 | 5 | 0 | 38 | |
| GSE46452 | RASSF3 | 283349 | 11 | 0 | 48 | |
| GSE47630 | RASSF3 | 283349 | 10 | 2 | 28 | |
| GSE54993 | RASSF3 | 283349 | 0 | 6 | 64 | |
| GSE54994 | RASSF3 | 283349 | 8 | 1 | 44 | |
| GSE60625 | RASSF3 | 283349 | 0 | 0 | 11 | |
| GSE74703 | RASSF3 | 283349 | 5 | 0 | 31 | |
| GSE74704 | RASSF3 | 283349 | 4 | 1 | 15 | |
| TCGA | RASSF3 | 283349 | 20 | 9 | 67 |
Total number of gains: 73; Total number of losses: 22; Total Number of normals: 393.
Somatic mutations of RASSF3:
Generating mutation plots.
Highly correlated genes for RASSF3:
Showing top 20/876 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RASSF3 | RNASE4 | 0.875385 | 3 | 0 | 3 |
| RASSF3 | CNN1 | 0.865996 | 3 | 0 | 3 |
| RASSF3 | SLMAP | 0.861057 | 5 | 0 | 5 |
| RASSF3 | FOXN3 | 0.856661 | 3 | 0 | 3 |
| RASSF3 | HMCN1 | 0.845407 | 3 | 0 | 3 |
| RASSF3 | TTLL7 | 0.829456 | 3 | 0 | 3 |
| RASSF3 | SYNC | 0.825599 | 3 | 0 | 3 |
| RASSF3 | MRGPRF | 0.825315 | 4 | 0 | 4 |
| RASSF3 | FILIP1 | 0.825028 | 4 | 0 | 4 |
| RASSF3 | FGL2 | 0.820841 | 4 | 0 | 4 |
| RASSF3 | DACT3 | 0.820212 | 3 | 0 | 3 |
| RASSF3 | CHRDL1 | 0.814936 | 4 | 0 | 4 |
| RASSF3 | MYOCD | 0.813194 | 5 | 0 | 5 |
| RASSF3 | ITGA1 | 0.81214 | 4 | 0 | 4 |
| RASSF3 | ARRB1 | 0.811957 | 4 | 0 | 4 |
| RASSF3 | PDE1A | 0.809371 | 4 | 0 | 4 |
| RASSF3 | FIBIN | 0.808406 | 3 | 0 | 3 |
| RASSF3 | CCDC69 | 0.805682 | 5 | 0 | 5 |
| RASSF3 | FXYD1 | 0.797179 | 3 | 0 | 3 |
| RASSF3 | JAM3 | 0.797058 | 4 | 0 | 4 |
For details and further investigation, click here
