| Full name: smoothelin like 2 | Alias Symbol: FLJ42461 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 342527 | HGNC ID: HGNC:24764 | Ensembl Gene: ENSG00000188176 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SMTNL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMTNL2 | 342527 | 229730_at | -0.4098 | 0.2929 | |
| GSE26886 | SMTNL2 | 342527 | 229730_at | -0.1543 | 0.2042 | |
| GSE45670 | SMTNL2 | 342527 | 229730_at | -0.8401 | 0.0000 | |
| GSE53622 | SMTNL2 | 342527 | 40084 | -2.3831 | 0.0000 | |
| GSE53624 | SMTNL2 | 342527 | 40084 | -2.4993 | 0.0000 | |
| GSE63941 | SMTNL2 | 342527 | 229730_at | -0.1264 | 0.6972 | |
| GSE77861 | SMTNL2 | 342527 | 229730_at | -0.1361 | 0.1266 | |
| GSE97050 | SMTNL2 | 342527 | A_24_P555066 | -0.3446 | 0.3545 | |
| SRP064894 | SMTNL2 | 342527 | RNAseq | -1.1230 | 0.0031 | |
| SRP133303 | SMTNL2 | 342527 | RNAseq | -2.7311 | 0.0000 | |
| SRP159526 | SMTNL2 | 342527 | RNAseq | -0.3108 | 0.7069 | |
| SRP219564 | SMTNL2 | 342527 | RNAseq | -0.6389 | 0.4067 | |
| TCGA | SMTNL2 | 342527 | RNAseq | -1.2504 | 0.0021 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by SMTNL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMTNL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMTNL2 | 342527 | 5 | 2 | 23 | |
| GSE20123 | SMTNL2 | 342527 | 5 | 3 | 22 | |
| GSE43470 | SMTNL2 | 342527 | 1 | 6 | 36 | |
| GSE46452 | SMTNL2 | 342527 | 34 | 1 | 24 | |
| GSE47630 | SMTNL2 | 342527 | 7 | 1 | 32 | |
| GSE54993 | SMTNL2 | 342527 | 4 | 3 | 63 | |
| GSE54994 | SMTNL2 | 342527 | 5 | 9 | 39 | |
| GSE60625 | SMTNL2 | 342527 | 4 | 0 | 7 | |
| GSE74703 | SMTNL2 | 342527 | 1 | 3 | 32 | |
| GSE74704 | SMTNL2 | 342527 | 3 | 1 | 16 | |
| TCGA | SMTNL2 | 342527 | 18 | 21 | 57 |
Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.
Somatic mutations of SMTNL2:
Generating mutation plots.
Highly correlated genes for SMTNL2:
Showing top 20/1180 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMTNL2 | RAB9B | 0.830526 | 5 | 0 | 5 |
| SMTNL2 | NPY1R | 0.817779 | 3 | 0 | 3 |
| SMTNL2 | CELF2 | 0.808445 | 5 | 0 | 5 |
| SMTNL2 | CASQ2 | 0.800799 | 5 | 0 | 5 |
| SMTNL2 | ASPA | 0.79739 | 6 | 0 | 6 |
| SMTNL2 | OGN | 0.785417 | 5 | 0 | 5 |
| SMTNL2 | TCF21 | 0.784095 | 5 | 0 | 5 |
| SMTNL2 | ABCA8 | 0.777831 | 5 | 0 | 5 |
| SMTNL2 | CYP4V2 | 0.774118 | 3 | 0 | 3 |
| SMTNL2 | XPC | 0.77366 | 3 | 0 | 3 |
| SMTNL2 | RECK | 0.772636 | 4 | 0 | 4 |
| SMTNL2 | PEG3 | 0.7713 | 3 | 0 | 3 |
| SMTNL2 | APOD | 0.77124 | 5 | 0 | 5 |
| SMTNL2 | TMEM100 | 0.770154 | 4 | 0 | 4 |
| SMTNL2 | MFAP4 | 0.769195 | 5 | 0 | 5 |
| SMTNL2 | ABI3BP | 0.768808 | 5 | 0 | 5 |
| SMTNL2 | PREX2 | 0.766527 | 4 | 0 | 4 |
| SMTNL2 | BHMT2 | 0.766063 | 5 | 0 | 5 |
| SMTNL2 | C1QTNF7 | 0.765743 | 5 | 0 | 5 |
| SMTNL2 | CLDND2 | 0.762057 | 3 | 0 | 3 |
For details and further investigation, click here
