| Full name: homeobox A3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p15.2 | ||
| Entrez ID: 3200 | HGNC ID: HGNC:5104 | Ensembl Gene: ENSG00000105997 | OMIM ID: 142954 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXA3 | 3200 | 235521_at | -0.7413 | 0.1410 | |
| GSE20347 | HOXA3 | 3200 | 208604_s_at | -0.1163 | 0.1125 | |
| GSE23400 | HOXA3 | 3200 | 208604_s_at | -0.1517 | 0.0002 | |
| GSE26886 | HOXA3 | 3200 | 235521_at | -0.4084 | 0.1683 | |
| GSE29001 | HOXA3 | 3200 | 208604_s_at | -0.0995 | 0.4510 | |
| GSE38129 | HOXA3 | 3200 | 208604_s_at | -0.1768 | 0.1139 | |
| GSE45670 | HOXA3 | 3200 | 235521_at | -0.7984 | 0.0003 | |
| GSE63941 | HOXA3 | 3200 | 235521_at | -1.6481 | 0.0954 | |
| GSE77861 | HOXA3 | 3200 | 208604_s_at | -0.0408 | 0.7907 | |
| GSE97050 | HOXA3 | 3200 | A_23_P501538 | -0.8123 | 0.1496 | |
| SRP007169 | HOXA3 | 3200 | RNAseq | -0.6875 | 0.2375 | |
| SRP064894 | HOXA3 | 3200 | RNAseq | -0.0970 | 0.6683 | |
| SRP133303 | HOXA3 | 3200 | RNAseq | -0.3997 | 0.1407 | |
| SRP159526 | HOXA3 | 3200 | RNAseq | 0.0988 | 0.8277 | |
| SRP193095 | HOXA3 | 3200 | RNAseq | -0.4850 | 0.0037 | |
| SRP219564 | HOXA3 | 3200 | RNAseq | -0.4081 | 0.3716 | |
| TCGA | HOXA3 | 3200 | RNAseq | 0.2349 | 0.1075 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HOXA3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HOXA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXA3 | 3200 | 16 | 1 | 13 | |
| GSE20123 | HOXA3 | 3200 | 16 | 1 | 13 | |
| GSE43470 | HOXA3 | 3200 | 4 | 0 | 39 | |
| GSE46452 | HOXA3 | 3200 | 10 | 2 | 47 | |
| GSE47630 | HOXA3 | 3200 | 8 | 1 | 31 | |
| GSE54993 | HOXA3 | 3200 | 0 | 6 | 64 | |
| GSE54994 | HOXA3 | 3200 | 21 | 2 | 30 | |
| GSE60625 | HOXA3 | 3200 | 0 | 0 | 11 | |
| GSE74703 | HOXA3 | 3200 | 4 | 0 | 32 | |
| GSE74704 | HOXA3 | 3200 | 10 | 1 | 9 | |
| TCGA | HOXA3 | 3200 | 54 | 7 | 35 |
Total number of gains: 143; Total number of losses: 21; Total Number of normals: 324.
Somatic mutations of HOXA3:
Generating mutation plots.
Highly correlated genes for HOXA3:
Showing top 20/755 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXA3 | SBF2 | 0.830581 | 3 | 0 | 3 |
| HOXA3 | AMOTL1 | 0.814539 | 3 | 0 | 3 |
| HOXA3 | MEIS2 | 0.809383 | 3 | 0 | 3 |
| HOXA3 | CHD9 | 0.771542 | 3 | 0 | 3 |
| HOXA3 | PHLDB1 | 0.760234 | 5 | 0 | 5 |
| HOXA3 | IQGAP1 | 0.754078 | 3 | 0 | 3 |
| HOXA3 | SP1 | 0.753144 | 3 | 0 | 3 |
| HOXA3 | XPA | 0.748959 | 3 | 0 | 3 |
| HOXA3 | STARD9 | 0.748051 | 3 | 0 | 3 |
| HOXA3 | ANGPTL1 | 0.746042 | 4 | 0 | 4 |
| HOXA3 | RFX2 | 0.743633 | 5 | 0 | 5 |
| HOXA3 | COL14A1 | 0.73952 | 4 | 0 | 4 |
| HOXA3 | PITPNM2 | 0.739201 | 3 | 0 | 3 |
| HOXA3 | CEP57 | 0.733634 | 3 | 0 | 3 |
| HOXA3 | ZNF570 | 0.732785 | 3 | 0 | 3 |
| HOXA3 | POLH | 0.732559 | 3 | 0 | 3 |
| HOXA3 | NPY1R | 0.72907 | 3 | 0 | 3 |
| HOXA3 | KLHDC8B | 0.724794 | 3 | 0 | 3 |
| HOXA3 | EIF4E3 | 0.722435 | 3 | 0 | 3 |
| HOXA3 | PBRM1 | 0.72112 | 3 | 0 | 3 |
For details and further investigation, click here
