| Full name: nuclear receptor subfamily 2 group F member 1 | Alias Symbol: EAR-3|COUP-TFI|TCFCOUP1|SVP44|COUPTF1 | ||
| Type: protein-coding gene | Cytoband: 5q15 | ||
| Entrez ID: 7025 | HGNC ID: HGNC:7975 | Ensembl Gene: ENSG00000175745 | OMIM ID: 132890 |
| Drug and gene relationship at DGIdb | |||
Expression of NR2F1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | NR2F1 | 7025 | 53931 | -1.1537 | 0.0000 | |
| GSE53624 | NR2F1 | 7025 | 53931 | -0.9898 | 0.0000 | |
| GSE97050 | NR2F1 | 7025 | A_33_P3403117 | -0.8087 | 0.1151 | |
| SRP007169 | NR2F1 | 7025 | RNAseq | 0.8309 | 0.2679 | |
| SRP064894 | NR2F1 | 7025 | RNAseq | -1.1633 | 0.0006 | |
| SRP133303 | NR2F1 | 7025 | RNAseq | -1.1442 | 0.0010 | |
| SRP159526 | NR2F1 | 7025 | RNAseq | -0.5108 | 0.2047 | |
| SRP193095 | NR2F1 | 7025 | RNAseq | 0.2486 | 0.4452 | |
| SRP219564 | NR2F1 | 7025 | RNAseq | -0.5150 | 0.4144 | |
| TCGA | NR2F1 | 7025 | RNAseq | -0.4946 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by NR2F1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR2F1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR2F1 | 7025 | 1 | 13 | 16 | |
| GSE20123 | NR2F1 | 7025 | 1 | 13 | 16 | |
| GSE43470 | NR2F1 | 7025 | 2 | 10 | 31 | |
| GSE46452 | NR2F1 | 7025 | 1 | 27 | 31 | |
| GSE47630 | NR2F1 | 7025 | 1 | 21 | 18 | |
| GSE54993 | NR2F1 | 7025 | 8 | 1 | 61 | |
| GSE54994 | NR2F1 | 7025 | 1 | 17 | 35 | |
| GSE60625 | NR2F1 | 7025 | 0 | 0 | 11 | |
| GSE74703 | NR2F1 | 7025 | 1 | 8 | 27 | |
| GSE74704 | NR2F1 | 7025 | 1 | 7 | 12 | |
| TCGA | NR2F1 | 7025 | 3 | 47 | 46 |
Total number of gains: 20; Total number of losses: 164; Total Number of normals: 304.
Somatic mutations of NR2F1:
Generating mutation plots.
Highly correlated genes for NR2F1:
Showing top 20/406 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR2F1 | TCF21 | 0.82369 | 3 | 0 | 3 |
| NR2F1 | ABCA8 | 0.814436 | 3 | 0 | 3 |
| NR2F1 | CLDN11 | 0.802724 | 3 | 0 | 3 |
| NR2F1 | CYP2U1 | 0.799877 | 3 | 0 | 3 |
| NR2F1 | LRRN4CL | 0.799233 | 3 | 0 | 3 |
| NR2F1 | RECK | 0.795658 | 3 | 0 | 3 |
| NR2F1 | C1QTNF7 | 0.792843 | 3 | 0 | 3 |
| NR2F1 | RGS5 | 0.783906 | 3 | 0 | 3 |
| NR2F1 | PREX2 | 0.780999 | 3 | 0 | 3 |
| NR2F1 | GFRA1 | 0.77929 | 3 | 0 | 3 |
| NR2F1 | CX3CR1 | 0.77862 | 3 | 0 | 3 |
| NR2F1 | ASPA | 0.778321 | 3 | 0 | 3 |
| NR2F1 | RERG | 0.777857 | 3 | 0 | 3 |
| NR2F1 | FHL5 | 0.774991 | 3 | 0 | 3 |
| NR2F1 | METTL7A | 0.773768 | 3 | 0 | 3 |
| NR2F1 | DIXDC1 | 0.767928 | 3 | 0 | 3 |
| NR2F1 | OGN | 0.766233 | 3 | 0 | 3 |
| NR2F1 | ABCA6 | 0.766071 | 3 | 0 | 3 |
| NR2F1 | RERGL | 0.764337 | 3 | 0 | 3 |
| NR2F1 | TMEM170B | 0.763347 | 3 | 0 | 3 |
For details and further investigation, click here
