| Full name: ankyrin repeat and sterile alpha motif domain containing 1B | Alias Symbol: EB-1|AIDA-1|cajalin-2|ANKS2 | ||
| Type: protein-coding gene | Cytoband: 12q23.1 | ||
| Entrez ID: 56899 | HGNC ID: HGNC:24600 | Ensembl Gene: ENSG00000185046 | OMIM ID: 607815 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKS1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKS1B | 56899 | 227439_at | -0.5944 | 0.1787 | |
| GSE20347 | ANKS1B | 56899 | 219989_s_at | -0.0229 | 0.6554 | |
| GSE23400 | ANKS1B | 56899 | 219989_s_at | -0.1435 | 0.0000 | |
| GSE26886 | ANKS1B | 56899 | 227440_at | 0.2606 | 0.0778 | |
| GSE29001 | ANKS1B | 56899 | 219989_s_at | -0.1362 | 0.1301 | |
| GSE38129 | ANKS1B | 56899 | 219989_s_at | -0.1001 | 0.0344 | |
| GSE45670 | ANKS1B | 56899 | 227440_at | -0.2292 | 0.0079 | |
| GSE53622 | ANKS1B | 56899 | 91695 | -1.7063 | 0.0000 | |
| GSE53624 | ANKS1B | 56899 | 91695 | -0.7782 | 0.0000 | |
| GSE63941 | ANKS1B | 56899 | 227440_at | 0.0923 | 0.5586 | |
| GSE77861 | ANKS1B | 56899 | 227440_at | -0.0402 | 0.6915 | |
| GSE97050 | ANKS1B | 56899 | A_33_P3258004 | -1.3961 | 0.1421 | |
| SRP064894 | ANKS1B | 56899 | RNAseq | -0.2955 | 0.5926 | |
| SRP133303 | ANKS1B | 56899 | RNAseq | -1.7529 | 0.0001 | |
| SRP159526 | ANKS1B | 56899 | RNAseq | -0.8598 | 0.1644 | |
| SRP193095 | ANKS1B | 56899 | RNAseq | -2.1010 | 0.0000 | |
| SRP219564 | ANKS1B | 56899 | RNAseq | -0.5332 | 0.5094 | |
| TCGA | ANKS1B | 56899 | RNAseq | -1.5110 | 0.0012 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ANKS1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKS1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKS1B | 56899 | 1 | 4 | 25 | |
| GSE20123 | ANKS1B | 56899 | 1 | 4 | 25 | |
| GSE43470 | ANKS1B | 56899 | 2 | 0 | 41 | |
| GSE46452 | ANKS1B | 56899 | 9 | 1 | 49 | |
| GSE47630 | ANKS1B | 56899 | 9 | 2 | 29 | |
| GSE54993 | ANKS1B | 56899 | 0 | 5 | 65 | |
| GSE54994 | ANKS1B | 56899 | 4 | 2 | 47 | |
| GSE60625 | ANKS1B | 56899 | 0 | 0 | 11 | |
| GSE74703 | ANKS1B | 56899 | 2 | 0 | 34 | |
| GSE74704 | ANKS1B | 56899 | 1 | 2 | 17 | |
| TCGA | ANKS1B | 56899 | 18 | 15 | 63 |
Total number of gains: 47; Total number of losses: 35; Total Number of normals: 406.
Somatic mutations of ANKS1B:
Generating mutation plots.
Highly correlated genes for ANKS1B:
Showing top 20/746 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKS1B | TTLL7 | 0.874515 | 3 | 0 | 3 |
| ANKS1B | MYL6 | 0.844762 | 3 | 0 | 3 |
| ANKS1B | VMAC | 0.807383 | 3 | 0 | 3 |
| ANKS1B | JAM2 | 0.775006 | 3 | 0 | 3 |
| ANKS1B | TMEM47 | 0.770317 | 3 | 0 | 3 |
| ANKS1B | MYLK | 0.769638 | 3 | 0 | 3 |
| ANKS1B | ADCY5 | 0.763042 | 4 | 0 | 4 |
| ANKS1B | TCEAL2 | 0.747078 | 4 | 0 | 4 |
| ANKS1B | GSN | 0.744992 | 4 | 0 | 3 |
| ANKS1B | TCEAL4 | 0.744127 | 3 | 0 | 3 |
| ANKS1B | PLA2G5 | 0.743867 | 5 | 0 | 5 |
| ANKS1B | SGCG | 0.739681 | 3 | 0 | 3 |
| ANKS1B | SPARCL1 | 0.739421 | 3 | 0 | 3 |
| ANKS1B | SMOC2 | 0.739096 | 3 | 0 | 3 |
| ANKS1B | MEIS2 | 0.735782 | 3 | 0 | 3 |
| ANKS1B | SPOP | 0.735028 | 3 | 0 | 3 |
| ANKS1B | PWAR5 | 0.734475 | 4 | 0 | 4 |
| ANKS1B | NEGR1 | 0.734381 | 4 | 0 | 3 |
| ANKS1B | REEP1 | 0.731606 | 3 | 0 | 3 |
| ANKS1B | DMD | 0.728206 | 3 | 0 | 3 |
For details and further investigation, click here
