| Full name: monoacylglycerol O-acyltransferase 2 | Alias Symbol: MGAT2|DGAT2L5|FLJ22644 | ||
| Type: protein-coding gene | Cytoband: 11q13.5 | ||
| Entrez ID: 80168 | HGNC ID: HGNC:23248 | Ensembl Gene: ENSG00000166391 | OMIM ID: 610270 |
| Drug and gene relationship at DGIdb | |||
Expression of MOGAT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOGAT2 | 80168 | 207491_at | -0.0632 | 0.8162 | |
| GSE20347 | MOGAT2 | 80168 | 207491_at | 0.0985 | 0.2534 | |
| GSE23400 | MOGAT2 | 80168 | 207491_at | -0.1178 | 0.0001 | |
| GSE26886 | MOGAT2 | 80168 | 207491_at | 0.0968 | 0.5079 | |
| GSE29001 | MOGAT2 | 80168 | 207491_at | -0.1325 | 0.3971 | |
| GSE38129 | MOGAT2 | 80168 | 207491_at | -0.0740 | 0.2849 | |
| GSE45670 | MOGAT2 | 80168 | 207491_at | -0.0654 | 0.4665 | |
| GSE53622 | MOGAT2 | 80168 | 20092 | -0.5353 | 0.0233 | |
| GSE53624 | MOGAT2 | 80168 | 20092 | -0.5711 | 0.0001 | |
| GSE63941 | MOGAT2 | 80168 | 207491_at | 0.2945 | 0.0921 | |
| GSE77861 | MOGAT2 | 80168 | 232428_at | -0.1168 | 0.2533 | |
| TCGA | MOGAT2 | 80168 | RNAseq | -0.3331 | 0.7828 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MOGAT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOGAT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOGAT2 | 80168 | 6 | 8 | 16 | |
| GSE20123 | MOGAT2 | 80168 | 6 | 7 | 17 | |
| GSE43470 | MOGAT2 | 80168 | 3 | 4 | 36 | |
| GSE46452 | MOGAT2 | 80168 | 7 | 22 | 30 | |
| GSE47630 | MOGAT2 | 80168 | 7 | 14 | 19 | |
| GSE54993 | MOGAT2 | 80168 | 8 | 2 | 60 | |
| GSE54994 | MOGAT2 | 80168 | 7 | 17 | 29 | |
| GSE60625 | MOGAT2 | 80168 | 4 | 3 | 4 | |
| GSE74703 | MOGAT2 | 80168 | 2 | 3 | 31 | |
| GSE74704 | MOGAT2 | 80168 | 4 | 3 | 13 | |
| TCGA | MOGAT2 | 80168 | 20 | 31 | 45 |
Total number of gains: 74; Total number of losses: 114; Total Number of normals: 300.
Somatic mutations of MOGAT2:
Generating mutation plots.
Highly correlated genes for MOGAT2:
Showing top 20/833 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOGAT2 | CD4 | 0.709036 | 3 | 0 | 3 |
| MOGAT2 | RBFADN | 0.694356 | 3 | 0 | 3 |
| MOGAT2 | NEURL1 | 0.692609 | 3 | 0 | 3 |
| MOGAT2 | LHX3 | 0.683619 | 4 | 0 | 4 |
| MOGAT2 | PTGIR | 0.663084 | 4 | 0 | 4 |
| MOGAT2 | ZNF287 | 0.662602 | 5 | 0 | 4 |
| MOGAT2 | RAB4B | 0.66191 | 3 | 0 | 3 |
| MOGAT2 | RNF167 | 0.661351 | 3 | 0 | 3 |
| MOGAT2 | CRISP1 | 0.658316 | 6 | 0 | 5 |
| MOGAT2 | CLC | 0.658246 | 3 | 0 | 3 |
| MOGAT2 | UNC79 | 0.65149 | 3 | 0 | 3 |
| MOGAT2 | CYP2A7 | 0.650753 | 5 | 0 | 4 |
| MOGAT2 | ART4 | 0.64944 | 5 | 0 | 5 |
| MOGAT2 | GFRA2 | 0.648591 | 5 | 0 | 4 |
| MOGAT2 | TCP10 | 0.648554 | 5 | 0 | 5 |
| MOGAT2 | MAGEB4 | 0.64668 | 3 | 0 | 3 |
| MOGAT2 | FOXN3-AS2 | 0.644096 | 5 | 0 | 3 |
| MOGAT2 | FOLH1 | 0.642931 | 4 | 0 | 4 |
| MOGAT2 | C1QL1 | 0.641744 | 5 | 0 | 5 |
| MOGAT2 | EPOR | 0.64014 | 6 | 0 | 5 |
For details and further investigation, click here
