| Full name: folate hydrolase 1 | Alias Symbol: PSM|PSMA|NAALAD1|NAALAdase|GCP2|GCPII | ||
| Type: protein-coding gene | Cytoband: 11p11.12 | ||
| Entrez ID: 2346 | HGNC ID: HGNC:3788 | Ensembl Gene: ENSG00000086205 | OMIM ID: 600934 |
| Drug and gene relationship at DGIdb | |||
Expression of FOLH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOLH1 | 2346 | 217483_at | -0.1021 | 0.6780 | |
| GSE20347 | FOLH1 | 2346 | 217483_at | 0.1397 | 0.1827 | |
| GSE23400 | FOLH1 | 2346 | 217483_at | -0.0590 | 0.1122 | |
| GSE26886 | FOLH1 | 2346 | 217483_at | -0.0624 | 0.6398 | |
| GSE29001 | FOLH1 | 2346 | 217483_at | -0.1487 | 0.4460 | |
| GSE38129 | FOLH1 | 2346 | 217483_at | 0.0162 | 0.8898 | |
| GSE45670 | FOLH1 | 2346 | 217483_at | 0.1193 | 0.2903 | |
| GSE53622 | FOLH1 | 2346 | 93697 | -0.1825 | 0.3413 | |
| GSE53624 | FOLH1 | 2346 | 93697 | 0.0238 | 0.8997 | |
| GSE63941 | FOLH1 | 2346 | 217483_at | 0.1395 | 0.6909 | |
| GSE77861 | FOLH1 | 2346 | 217483_at | -0.1044 | 0.3746 | |
| GSE97050 | FOLH1 | 2346 | A_33_P3332337 | -0.0982 | 0.9349 | |
| SRP007169 | FOLH1 | 2346 | RNAseq | 2.5967 | 0.0004 | |
| SRP064894 | FOLH1 | 2346 | RNAseq | -0.4734 | 0.3360 | |
| SRP133303 | FOLH1 | 2346 | RNAseq | -0.2752 | 0.5492 | |
| SRP159526 | FOLH1 | 2346 | RNAseq | 0.9403 | 0.0311 | |
| SRP193095 | FOLH1 | 2346 | RNAseq | 0.3986 | 0.2587 | |
| SRP219564 | FOLH1 | 2346 | RNAseq | 0.6963 | 0.2386 | |
| TCGA | FOLH1 | 2346 | RNAseq | 0.9027 | 0.0011 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FOLH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOLH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOLH1 | 2346 | 2 | 8 | 20 | |
| GSE20123 | FOLH1 | 2346 | 1 | 7 | 22 | |
| GSE43470 | FOLH1 | 2346 | 2 | 4 | 37 | |
| GSE46452 | FOLH1 | 2346 | 9 | 5 | 45 | |
| GSE47630 | FOLH1 | 2346 | 3 | 10 | 27 | |
| GSE54993 | FOLH1 | 2346 | 3 | 0 | 67 | |
| GSE54994 | FOLH1 | 2346 | 1 | 11 | 41 | |
| GSE60625 | FOLH1 | 2346 | 0 | 0 | 11 | |
| GSE74703 | FOLH1 | 2346 | 2 | 2 | 32 | |
| GSE74704 | FOLH1 | 2346 | 1 | 6 | 13 | |
| TCGA | FOLH1 | 2346 | 14 | 17 | 65 |
Total number of gains: 38; Total number of losses: 70; Total Number of normals: 380.
Somatic mutations of FOLH1:
Generating mutation plots.
Highly correlated genes for FOLH1:
Showing top 20/610 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOLH1 | CCZ1 | 0.800359 | 4 | 0 | 4 |
| FOLH1 | IL1RAPL2 | 0.780866 | 4 | 0 | 4 |
| FOLH1 | OR10H3 | 0.777447 | 4 | 0 | 4 |
| FOLH1 | AQP6 | 0.765448 | 5 | 0 | 5 |
| FOLH1 | IFNA4 | 0.764345 | 5 | 0 | 5 |
| FOLH1 | DMC1 | 0.762201 | 3 | 0 | 3 |
| FOLH1 | DAB1 | 0.752426 | 5 | 0 | 5 |
| FOLH1 | NEUROD2 | 0.750191 | 4 | 0 | 4 |
| FOLH1 | KIF17 | 0.74987 | 4 | 0 | 4 |
| FOLH1 | KIR2DS2 | 0.745896 | 5 | 0 | 5 |
| FOLH1 | COLEC10 | 0.741522 | 4 | 0 | 4 |
| FOLH1 | OR1F1 | 0.738478 | 5 | 0 | 5 |
| FOLH1 | CER1 | 0.738296 | 4 | 0 | 4 |
| FOLH1 | TRAPPC9 | 0.735049 | 4 | 0 | 4 |
| FOLH1 | CDC25C | 0.730395 | 3 | 0 | 3 |
| FOLH1 | KIR2DS5 | 0.728541 | 4 | 0 | 4 |
| FOLH1 | AICDA | 0.728442 | 4 | 0 | 4 |
| FOLH1 | IFNA14 | 0.724884 | 5 | 0 | 5 |
| FOLH1 | NTNG1 | 0.723691 | 4 | 0 | 4 |
| FOLH1 | TNFSF11 | 0.723136 | 5 | 0 | 5 |
For details and further investigation, click here
