| Full name: ADP-ribosyltransferase 4 (Dombrock blood group) | Alias Symbol: DOK1|CD297 | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 420 | HGNC ID: HGNC:726 | Ensembl Gene: ENSG00000111339 | OMIM ID: 110600 |
| Drug and gene relationship at DGIdb | |||
Expression of ART4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ART4 | 420 | 207220_at | -0.0339 | 0.9145 | |
| GSE20347 | ART4 | 420 | 207220_at | 0.1312 | 0.0679 | |
| GSE23400 | ART4 | 420 | 207220_at | -0.1025 | 0.0281 | |
| GSE26886 | ART4 | 420 | 207220_at | 0.0901 | 0.3835 | |
| GSE29001 | ART4 | 420 | 207220_at | -0.0673 | 0.5859 | |
| GSE38129 | ART4 | 420 | 207220_at | -0.0001 | 0.9991 | |
| GSE45670 | ART4 | 420 | 207220_at | -0.1262 | 0.0989 | |
| GSE53622 | ART4 | 420 | 50971 | -0.8812 | 0.0000 | |
| GSE53624 | ART4 | 420 | 50971 | -0.5103 | 0.0000 | |
| GSE63941 | ART4 | 420 | 207220_at | 0.1694 | 0.2490 | |
| GSE77861 | ART4 | 420 | 207220_at | -0.0566 | 0.6021 | |
| GSE97050 | ART4 | 420 | A_23_P116902 | -0.1037 | 0.6745 | |
| SRP133303 | ART4 | 420 | RNAseq | -0.5475 | 0.0686 | |
| TCGA | ART4 | 420 | RNAseq | -2.0373 | 0.0543 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ART4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ART4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ART4 | 420 | 6 | 2 | 22 | |
| GSE20123 | ART4 | 420 | 6 | 2 | 22 | |
| GSE43470 | ART4 | 420 | 9 | 4 | 30 | |
| GSE46452 | ART4 | 420 | 10 | 1 | 48 | |
| GSE47630 | ART4 | 420 | 14 | 1 | 25 | |
| GSE54993 | ART4 | 420 | 1 | 9 | 60 | |
| GSE54994 | ART4 | 420 | 10 | 2 | 41 | |
| GSE60625 | ART4 | 420 | 0 | 1 | 10 | |
| GSE74703 | ART4 | 420 | 9 | 3 | 24 | |
| GSE74704 | ART4 | 420 | 4 | 1 | 15 | |
| TCGA | ART4 | 420 | 41 | 5 | 50 |
Total number of gains: 110; Total number of losses: 31; Total Number of normals: 347.
Somatic mutations of ART4:
Generating mutation plots.
Highly correlated genes for ART4:
Showing top 20/660 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ART4 | NOS1 | 0.725639 | 4 | 0 | 3 |
| ART4 | OR52A1 | 0.715275 | 4 | 0 | 4 |
| ART4 | CABIN1 | 0.707331 | 3 | 0 | 3 |
| ART4 | KHDRBS2 | 0.70697 | 5 | 0 | 5 |
| ART4 | ARPP21 | 0.703211 | 4 | 0 | 4 |
| ART4 | LUZP4 | 0.696705 | 5 | 0 | 5 |
| ART4 | OPRM1 | 0.695228 | 5 | 0 | 5 |
| ART4 | CCDC30 | 0.692736 | 7 | 0 | 7 |
| ART4 | HHLA1 | 0.69209 | 5 | 0 | 5 |
| ART4 | SST | 0.691146 | 3 | 0 | 3 |
| ART4 | IL1RAPL2 | 0.683526 | 5 | 0 | 5 |
| ART4 | MAGI1 | 0.677721 | 4 | 0 | 4 |
| ART4 | BCORL1 | 0.677687 | 4 | 0 | 4 |
| ART4 | BMPR1B | 0.677145 | 4 | 0 | 3 |
| ART4 | GABRR2 | 0.67711 | 5 | 0 | 5 |
| ART4 | CCL14 | 0.674244 | 3 | 0 | 3 |
| ART4 | GPC5 | 0.672652 | 3 | 0 | 3 |
| ART4 | TESPA1 | 0.670608 | 4 | 0 | 4 |
| ART4 | HNF4G | 0.669267 | 4 | 0 | 4 |
| ART4 | KIR2DL2 | 0.669208 | 5 | 0 | 5 |
For details and further investigation, click here
