| Full name: RAB4B, member RAS oncogene family | Alias Symbol: FLJ78649|MGC52123 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 53916 | HGNC ID: HGNC:9782 | Ensembl Gene: ENSG00000167578 | OMIM ID: 612945 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB4B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB4B | 53916 | 237257_at | -0.2427 | 0.5813 | |
| GSE26886 | RAB4B | 53916 | 237257_at | -0.4190 | 0.0485 | |
| GSE45670 | RAB4B | 53916 | 237257_at | 0.0865 | 0.4639 | |
| GSE63941 | RAB4B | 53916 | 237257_at | 0.7816 | 0.0035 | |
| GSE77861 | RAB4B | 53916 | 237257_at | -0.1928 | 0.3914 | |
| GSE97050 | RAB4B | 53916 | A_23_P16116 | -0.0146 | 0.9700 | |
| SRP007169 | RAB4B | 53916 | RNAseq | -1.5765 | 0.0000 | |
| SRP008496 | RAB4B | 53916 | RNAseq | -1.5684 | 0.0000 | |
| SRP064894 | RAB4B | 53916 | RNAseq | 0.1821 | 0.4945 | |
| SRP133303 | RAB4B | 53916 | RNAseq | -0.3033 | 0.0440 | |
| SRP159526 | RAB4B | 53916 | RNAseq | 0.1673 | 0.6559 | |
| SRP193095 | RAB4B | 53916 | RNAseq | -0.5959 | 0.0000 | |
| SRP219564 | RAB4B | 53916 | RNAseq | 0.1388 | 0.6109 | |
| TCGA | RAB4B | 53916 | RNAseq | 0.0071 | 0.9252 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RAB4B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RAB4B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB4B | 53916 | 4 | 5 | 21 | |
| GSE20123 | RAB4B | 53916 | 4 | 4 | 22 | |
| GSE43470 | RAB4B | 53916 | 3 | 9 | 31 | |
| GSE46452 | RAB4B | 53916 | 48 | 1 | 10 | |
| GSE47630 | RAB4B | 53916 | 9 | 5 | 26 | |
| GSE54993 | RAB4B | 53916 | 17 | 4 | 49 | |
| GSE54994 | RAB4B | 53916 | 8 | 9 | 36 | |
| GSE60625 | RAB4B | 53916 | 9 | 0 | 2 | |
| GSE74703 | RAB4B | 53916 | 3 | 6 | 27 | |
| GSE74704 | RAB4B | 53916 | 4 | 2 | 14 | |
| TCGA | RAB4B | 53916 | 14 | 16 | 66 |
Total number of gains: 123; Total number of losses: 61; Total Number of normals: 304.
Somatic mutations of RAB4B:
Generating mutation plots.
Highly correlated genes for RAB4B:
Showing top 20/423 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB4B | SEMA4A | 0.765877 | 4 | 0 | 4 |
| RAB4B | HK1 | 0.7602 | 3 | 0 | 3 |
| RAB4B | KCNC4 | 0.759456 | 3 | 0 | 3 |
| RAB4B | GHDC | 0.749556 | 3 | 0 | 3 |
| RAB4B | SLC11A1 | 0.746677 | 3 | 0 | 3 |
| RAB4B | PPP2R1A | 0.740467 | 4 | 0 | 4 |
| RAB4B | PRSS36 | 0.738955 | 3 | 0 | 3 |
| RAB4B | PPP4C | 0.734884 | 3 | 0 | 3 |
| RAB4B | SLCO2A1 | 0.730913 | 3 | 0 | 3 |
| RAB4B | COX15 | 0.727267 | 3 | 0 | 3 |
| RAB4B | ZFPL1 | 0.724969 | 4 | 0 | 4 |
| RAB4B | CD1E | 0.721084 | 3 | 0 | 3 |
| RAB4B | AAAS | 0.72024 | 4 | 0 | 4 |
| RAB4B | PTPRT | 0.720042 | 3 | 0 | 3 |
| RAB4B | VRK3 | 0.72002 | 3 | 0 | 3 |
| RAB4B | PRSS58 | 0.71375 | 3 | 0 | 3 |
| RAB4B | SH3BGRL3 | 0.712126 | 3 | 0 | 3 |
| RAB4B | SLC25A35 | 0.711181 | 5 | 0 | 5 |
| RAB4B | APEH | 0.71013 | 3 | 0 | 3 |
| RAB4B | C11orf68 | 0.705528 | 3 | 0 | 3 |
For details and further investigation, click here
