| Full name: cysteine rich secretory protein 1 | Alias Symbol: CRISP-1|ARP|HUMARP|HSCRISP1D|HSCRISP1G | ||
| Type: protein-coding gene | Cytoband: 6p12.3 | ||
| Entrez ID: 167 | HGNC ID: HGNC:304 | Ensembl Gene: ENSG00000124812 | OMIM ID: 601193 |
| Drug and gene relationship at DGIdb | |||
Expression of CRISP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRISP1 | 167 | 207032_s_at | -0.1218 | 0.5685 | |
| GSE20347 | CRISP1 | 167 | 207032_s_at | -0.0202 | 0.8124 | |
| GSE23400 | CRISP1 | 167 | 207032_s_at | -0.1654 | 0.0000 | |
| GSE26886 | CRISP1 | 167 | 207032_s_at | -0.0257 | 0.7995 | |
| GSE29001 | CRISP1 | 167 | 207032_s_at | -0.2193 | 0.1461 | |
| GSE38129 | CRISP1 | 167 | 207032_s_at | -0.1654 | 0.0329 | |
| GSE45670 | CRISP1 | 167 | 207032_s_at | 0.1925 | 0.0345 | |
| GSE53622 | CRISP1 | 167 | 39459 | 0.0651 | 0.5354 | |
| GSE53624 | CRISP1 | 167 | 39459 | 0.1344 | 0.1266 | |
| GSE63941 | CRISP1 | 167 | 207032_s_at | 0.3069 | 0.0075 | |
| GSE77861 | CRISP1 | 167 | 207032_s_at | -0.0752 | 0.3970 | |
| TCGA | CRISP1 | 167 | RNAseq | 1.3541 | 0.5575 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRISP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRISP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRISP1 | 167 | 5 | 2 | 23 | |
| GSE20123 | CRISP1 | 167 | 5 | 2 | 23 | |
| GSE43470 | CRISP1 | 167 | 5 | 0 | 38 | |
| GSE46452 | CRISP1 | 167 | 2 | 10 | 47 | |
| GSE47630 | CRISP1 | 167 | 7 | 5 | 28 | |
| GSE54993 | CRISP1 | 167 | 3 | 1 | 66 | |
| GSE54994 | CRISP1 | 167 | 8 | 4 | 41 | |
| GSE60625 | CRISP1 | 167 | 0 | 3 | 8 | |
| GSE74703 | CRISP1 | 167 | 5 | 0 | 31 | |
| GSE74704 | CRISP1 | 167 | 2 | 1 | 17 | |
| TCGA | CRISP1 | 167 | 21 | 12 | 63 |
Total number of gains: 63; Total number of losses: 40; Total Number of normals: 385.
Somatic mutations of CRISP1:
Generating mutation plots.
Highly correlated genes for CRISP1:
Showing top 20/1207 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRISP1 | CPA2 | 0.73277 | 3 | 0 | 3 |
| CRISP1 | PSG9 | 0.73082 | 3 | 0 | 3 |
| CRISP1 | RNF17 | 0.730152 | 4 | 0 | 4 |
| CRISP1 | NEURL1 | 0.724098 | 4 | 0 | 4 |
| CRISP1 | CBL | 0.723012 | 4 | 0 | 4 |
| CRISP1 | OR2H2 | 0.709848 | 6 | 0 | 6 |
| CRISP1 | CRP | 0.708137 | 4 | 0 | 4 |
| CRISP1 | CCDC7 | 0.707524 | 4 | 0 | 4 |
| CRISP1 | KIR2DS2 | 0.707293 | 6 | 0 | 5 |
| CRISP1 | GJB4 | 0.707107 | 6 | 0 | 5 |
| CRISP1 | GP1BA | 0.706776 | 4 | 0 | 4 |
| CRISP1 | HECW1 | 0.69967 | 4 | 0 | 4 |
| CRISP1 | DENND1C | 0.698617 | 3 | 0 | 3 |
| CRISP1 | CADM3 | 0.697187 | 5 | 0 | 5 |
| CRISP1 | CCDC87 | 0.695126 | 4 | 0 | 4 |
| CRISP1 | MT4 | 0.693861 | 4 | 0 | 4 |
| CRISP1 | SLC10A1 | 0.692701 | 5 | 0 | 4 |
| CRISP1 | OR12D3 | 0.691951 | 4 | 0 | 4 |
| CRISP1 | CAMKV | 0.690628 | 6 | 0 | 5 |
| CRISP1 | RASGRF1 | 0.689935 | 6 | 0 | 6 |
For details and further investigation, click here
