| Full name: mitochondrial ribosomal protein L24 | Alias Symbol: MRP-L18 | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 79590 | HGNC ID: HGNC:14037 | Ensembl Gene: ENSG00000143314 | OMIM ID: 611836 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL24 | 79590 | 218270_at | 0.3994 | 0.2038 | |
| GSE20347 | MRPL24 | 79590 | 218270_at | 0.3844 | 0.0009 | |
| GSE23400 | MRPL24 | 79590 | 218270_at | 0.3092 | 0.0000 | |
| GSE26886 | MRPL24 | 79590 | 218270_at | 1.0081 | 0.0000 | |
| GSE29001 | MRPL24 | 79590 | 218270_at | 0.2801 | 0.3652 | |
| GSE38129 | MRPL24 | 79590 | 218270_at | 0.3320 | 0.0078 | |
| GSE45670 | MRPL24 | 79590 | 218270_at | 0.1635 | 0.1226 | |
| GSE53622 | MRPL24 | 79590 | 75658 | 0.3081 | 0.0000 | |
| GSE53624 | MRPL24 | 79590 | 75658 | 0.4649 | 0.0000 | |
| GSE63941 | MRPL24 | 79590 | 218270_at | 0.9622 | 0.0030 | |
| GSE77861 | MRPL24 | 79590 | 218270_at | 0.4626 | 0.0097 | |
| GSE97050 | MRPL24 | 79590 | A_23_P137848 | 0.1180 | 0.7970 | |
| SRP007169 | MRPL24 | 79590 | RNAseq | -0.1050 | 0.7851 | |
| SRP008496 | MRPL24 | 79590 | RNAseq | 0.3086 | 0.2063 | |
| SRP064894 | MRPL24 | 79590 | RNAseq | 0.5692 | 0.0894 | |
| SRP133303 | MRPL24 | 79590 | RNAseq | 0.4967 | 0.0113 | |
| SRP159526 | MRPL24 | 79590 | RNAseq | 0.8895 | 0.0004 | |
| SRP193095 | MRPL24 | 79590 | RNAseq | 0.3263 | 0.0165 | |
| SRP219564 | MRPL24 | 79590 | RNAseq | 0.1710 | 0.7004 | |
| TCGA | MRPL24 | 79590 | RNAseq | 0.1370 | 0.0306 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPL24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL24 | 79590 | 12 | 0 | 18 | |
| GSE20123 | MRPL24 | 79590 | 12 | 0 | 18 | |
| GSE43470 | MRPL24 | 79590 | 7 | 2 | 34 | |
| GSE46452 | MRPL24 | 79590 | 2 | 1 | 56 | |
| GSE47630 | MRPL24 | 79590 | 14 | 0 | 26 | |
| GSE54993 | MRPL24 | 79590 | 0 | 5 | 65 | |
| GSE54994 | MRPL24 | 79590 | 16 | 0 | 37 | |
| GSE60625 | MRPL24 | 79590 | 0 | 0 | 11 | |
| GSE74703 | MRPL24 | 79590 | 7 | 2 | 27 | |
| GSE74704 | MRPL24 | 79590 | 6 | 0 | 14 | |
| TCGA | MRPL24 | 79590 | 38 | 2 | 56 |
Total number of gains: 114; Total number of losses: 12; Total Number of normals: 362.
Somatic mutations of MRPL24:
Generating mutation plots.
Highly correlated genes for MRPL24:
Showing top 20/1488 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL24 | PPP2R2D | 0.81927 | 3 | 0 | 3 |
| MRPL24 | FAM168A | 0.754339 | 3 | 0 | 3 |
| MRPL24 | RBMX | 0.751079 | 3 | 0 | 3 |
| MRPL24 | HADH | 0.74911 | 3 | 0 | 3 |
| MRPL24 | CLIP2 | 0.748406 | 4 | 0 | 3 |
| MRPL24 | HES4 | 0.743341 | 3 | 0 | 3 |
| MRPL24 | NENF | 0.740334 | 9 | 0 | 9 |
| MRPL24 | ZNF418 | 0.733446 | 3 | 0 | 3 |
| MRPL24 | ZBTB37 | 0.729111 | 3 | 0 | 3 |
| MRPL24 | RPS24 | 0.727374 | 3 | 0 | 3 |
| MRPL24 | NEK3 | 0.722968 | 3 | 0 | 3 |
| MRPL24 | ZSCAN29 | 0.722775 | 3 | 0 | 3 |
| MRPL24 | CBLB | 0.721017 | 5 | 0 | 4 |
| MRPL24 | TTC30B | 0.720944 | 4 | 0 | 4 |
| MRPL24 | SRSF6 | 0.718632 | 4 | 0 | 3 |
| MRPL24 | BOLA1 | 0.717857 | 12 | 0 | 12 |
| MRPL24 | ZC3HC1 | 0.715063 | 7 | 0 | 7 |
| MRPL24 | SUZ12 | 0.710408 | 5 | 0 | 4 |
| MRPL24 | DDX20 | 0.708478 | 4 | 0 | 4 |
| MRPL24 | PHF8 | 0.708118 | 3 | 0 | 3 |
For details and further investigation, click here
