| Full name: protein phosphatase 2 regulatory subunit Bdelta | Alias Symbol: MDS026|B55delta|B55D | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 55844 | HGNC ID: HGNC:23732 | Ensembl Gene: ENSG00000175470 | OMIM ID: 613992 |
| Drug and gene relationship at DGIdb | |||
PPP2R2D involved pathways:
Expression of PPP2R2D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP2R2D | 55844 | 221772_s_at | 0.1488 | 0.6051 | |
| GSE20347 | PPP2R2D | 55844 | 221772_s_at | 0.2169 | 0.1517 | |
| GSE23400 | PPP2R2D | 55844 | 221772_s_at | 0.0773 | 0.1338 | |
| GSE26886 | PPP2R2D | 55844 | 221772_s_at | 0.2531 | 0.3781 | |
| GSE29001 | PPP2R2D | 55844 | 221772_s_at | 0.0733 | 0.7572 | |
| GSE38129 | PPP2R2D | 55844 | 221772_s_at | 0.1188 | 0.3471 | |
| GSE45670 | PPP2R2D | 55844 | 221772_s_at | 0.1458 | 0.1264 | |
| GSE53622 | PPP2R2D | 55844 | 11546 | 0.2042 | 0.0022 | |
| GSE53624 | PPP2R2D | 55844 | 11546 | 0.1980 | 0.0000 | |
| GSE63941 | PPP2R2D | 55844 | 221772_s_at | 0.8919 | 0.0501 | |
| GSE77861 | PPP2R2D | 55844 | 221772_s_at | 0.0008 | 0.9976 | |
| GSE97050 | PPP2R2D | 55844 | A_23_P135778 | 0.1578 | 0.5211 | |
| SRP007169 | PPP2R2D | 55844 | RNAseq | -0.2098 | 0.6235 | |
| SRP008496 | PPP2R2D | 55844 | RNAseq | 0.0535 | 0.8567 | |
| SRP064894 | PPP2R2D | 55844 | RNAseq | -0.1086 | 0.3914 | |
| SRP133303 | PPP2R2D | 55844 | RNAseq | 0.3458 | 0.0201 | |
| SRP159526 | PPP2R2D | 55844 | RNAseq | 0.1549 | 0.4509 | |
| SRP193095 | PPP2R2D | 55844 | RNAseq | 0.1984 | 0.0327 | |
| SRP219564 | PPP2R2D | 55844 | RNAseq | 0.0621 | 0.8383 | |
| TCGA | PPP2R2D | 55844 | RNAseq | -0.0103 | 0.8451 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPP2R2D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP2R2D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP2R2D | 55844 | 2 | 9 | 19 | |
| GSE20123 | PPP2R2D | 55844 | 2 | 9 | 19 | |
| GSE43470 | PPP2R2D | 55844 | 0 | 10 | 33 | |
| GSE46452 | PPP2R2D | 55844 | 1 | 11 | 47 | |
| GSE47630 | PPP2R2D | 55844 | 4 | 13 | 23 | |
| GSE54993 | PPP2R2D | 55844 | 7 | 1 | 62 | |
| GSE54994 | PPP2R2D | 55844 | 1 | 10 | 42 | |
| GSE60625 | PPP2R2D | 55844 | 0 | 0 | 11 | |
| GSE74703 | PPP2R2D | 55844 | 0 | 6 | 30 | |
| GSE74704 | PPP2R2D | 55844 | 2 | 4 | 14 | |
| TCGA | PPP2R2D | 55844 | 7 | 28 | 61 |
Total number of gains: 26; Total number of losses: 101; Total Number of normals: 361.
Somatic mutations of PPP2R2D:
Generating mutation plots.
Highly correlated genes for PPP2R2D:
Showing top 20/365 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP2R2D | MRPL24 | 0.81927 | 3 | 0 | 3 |
| PPP2R2D | INO80E | 0.763071 | 3 | 0 | 3 |
| PPP2R2D | PIP4K2B | 0.734991 | 3 | 0 | 3 |
| PPP2R2D | NAPG | 0.734716 | 3 | 0 | 3 |
| PPP2R2D | ZC3HC1 | 0.734689 | 3 | 0 | 3 |
| PPP2R2D | FH | 0.732381 | 3 | 0 | 3 |
| PPP2R2D | ZNF628 | 0.725821 | 3 | 0 | 3 |
| PPP2R2D | FZR1 | 0.720851 | 3 | 0 | 3 |
| PPP2R2D | POMZP3 | 0.720531 | 3 | 0 | 3 |
| PPP2R2D | ABHD2 | 0.719205 | 3 | 0 | 3 |
| PPP2R2D | SOX13 | 0.717469 | 3 | 0 | 3 |
| PPP2R2D | TTLL1 | 0.714932 | 3 | 0 | 3 |
| PPP2R2D | GOSR1 | 0.712838 | 3 | 0 | 3 |
| PPP2R2D | UBIAD1 | 0.70748 | 4 | 0 | 3 |
| PPP2R2D | ZMYM6 | 0.707311 | 3 | 0 | 3 |
| PPP2R2D | HNRNPA1 | 0.707062 | 3 | 0 | 3 |
| PPP2R2D | GAA | 0.706353 | 3 | 0 | 3 |
| PPP2R2D | TMEM41A | 0.706231 | 3 | 0 | 3 |
| PPP2R2D | ZGPAT | 0.705807 | 3 | 0 | 3 |
| PPP2R2D | ASAP2 | 0.704754 | 3 | 0 | 3 |
For details and further investigation, click here
